- Peroxisome Proliferator-activated Receptors (PPARs) in Diabetic Nephropathy
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Park CW
- KMID: 1575476
- J Korean Diabetes Assoc.
- 2004 Jun;28(3):149-159.
No abstract available. -
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- Peroxisome Proliferator Activated Receptor-delta (PPAR-delta)
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Choi KM
- KMID: 2222516
- J Korean Diabetes Assoc.
- 2007 Jul;31(4):297-301.
- doi: 10.4093/jkda.2007.31.4.297
The development of novel treatments for the metabolic syndrome is imminent for decreasing the prevalence of type 2 diabetes and cardiovascular disease. Peroxisome proliferator-activated receptors (PPARs) are members of the... -
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- Effects of Sulfonylureas on Peroxisome Proliferator-Activated Receptor gamma Activity and on Glucose Uptake by Thiazolidinediones
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Lee KW, Ku YH, Kim M, Ahn BY, Chung SS, Park KS
- KMID: 2281640
- Diabetes Metab J.
- 2011 Aug;35(4):340-347.
- doi: 10.4093/dmj.2011.35.4.340
BACKGROUND: Sulfonylurea primarily stimulates insulin secretion by binding to its receptor on the pancreatic beta-cells. Recent studies have suggested that sulfonylureas induce insulin sensitivity through peroxisome proliferator-activated receptor gamma (PPARgamma),... -
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- Transporters and Nuclear Hormone Receptors associated with Cholesterol Metabolism in Gallbladder Epithelial Cells
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Lee J
- KMID: 2168079
- Hanyang Med Rev.
- 2007 Feb;27(1):20-28.
Bile is concentrated in the gallbladder, and is often supersaturated in terms of cholesterol concentration. Such high levels of cholesterol in gallbladder bile has clinical implications with respect to cholesterol... -
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- Safety and Efficacy of Peroxisome Proliferator-Activated Receptor-alpha Agonist for Treating Cardiovascular Disease
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Kang YR, Kwak CH, Hwang JY
- KMID: 2227034
- Korean Circ J.
- 2007 Dec;37(12):599-608.
- doi: 10.4070/kcj.2007.37.12.599
Peroxisome proliferator-activated receptor (PPAR)-alpha belongs to the nuclear family of ligand-activated transcriptional factors. The main role of PPAR-alpha is to activate the expression of the genes that are involved in... -
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- Downregulation of Peroxisome Proliferator-Activated Receptor (PPAR)alpha, PPARgamma, and Phosphoglycerate Mutase 2 in Prostate Cancer
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Cho HJ, Kim DY, Kim JW, Yoo TK, Yang EK
- KMID: 2294244
- Korean J Urol.
- 2006 Jun;47(6):661-666.
- doi: 10.4111/kju.2006.47.6.661
PURPOSE: To evaluate whether factors related to lipid and glucose metabolism have a potential role in the progression of prostate cancer, we measured the mRNA levels of the peroxisome proliferator-activated... -
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- Peroxisome Proliferator-Activated Receptor (PPAR) alpha/gamma Agonist
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Lee J
- KMID: 2269258
- Korean J Med.
- 2014 Jul;87(1):19-25.
Peroxisome proliferator-activated receptor (PPAR) agonists improve glucose control and insulin sensitivity, reduce concentrations of atherogenic lipoproteins, and decrease circulating levels of inflammatory mediators. PPAR activation is considered an important pharmacologic... -
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- Expression of the Peroxisome-proliferator-activated Receptor-gamma in Human Gastric Cancer
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Cho DH, Shin DG, Kang SG, Park SS, Yoon J, Kim IM, Yoon SM, Lee YK, Lee YJ, Yang DH, Cho IH
- KMID: 1565017
- J Korean Gastric Cancer Assoc.
- 2006 Dec;6(4):250-256.
PURPOSE: Recently, interest in peroxisome-proliferator-activated receptors (PPAR) has increased, although clinical studies of the effect of PPAR-gamma expression on gastric cancer have not been reported yet. In this study, we... -
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- Regulation of Muscle Pyruvate Dehydrogenase Complex in Insulin Resistance: Effects of Exercise and Dichloroacetate
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Constantin-Teodosiu D
- KMID: 1965976
- Diabetes Metab J.
- 2013 Oct;37(5):301-314.
- doi: 10.4093/dmj.2013.37.5.301
Since the mitochondrial pyruvate dehydrogenase complex (PDC) controls the rate of carbohydrate oxidation, impairment of PDC activity mediated by high-fat intake has been advocated as a causative factor for the... -
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- Genetic Polymorphisms in the HTR2C and Peroxisome Proliferator-Activated Receptors Are Not Associated with Metabolic Syndrome in Patients with Schizophrenia Taking Clozapine
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Kang SH, Lee JI, Chang AK, Joo YH, Kim CY, Kim SY
- KMID: 2316094
- Psychiatry Investig.
- 2011 Sep;8(3):262-268.
OBJECTIVE: Genetic variation in the serotonin-2C receptor encoded by the HTR2C gene is one of the genetic determinants of antipsychotic-induced weight gain. Peroxisome proliferator-activated receptors are nuclear receptors regulating the... -
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- Effects of Co-treatment with Dexamethasone and Troglitazone on Transcription and Secretion of IL-8 in the A549 Airway Epithelial Cells
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- KMID: 2234553
- Korean J Asthma Allergy Clin Immunol.
- 2008 Dec;28(4):292-297.
BACKGROUND: Glucocorticoid is a widely used anti-inflammatory agent in a variety of diseases. Recently, peroxisome proliferator activated receptor gamma (PPAR gamma) ligand has been shown to exert a potential anti-inflammatory... -
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- Neither polyphenol-rich red wine nor fenofibrate affects the onset of type-1 diabetes mellitus in the BB rat
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Ã…vall K, Berggren P, Juntti-Berggren L
- KMID: 2420825
- Lab Anim Res.
- 2018 Sep;34(3):126-131.
- doi: 10.5625/lar.2018.34.3.126
Serum levels of the pro-inflammatory apolipoprotein CIII (apoCIII) are increased in type-1 diabetic (T1D) patients and when β-cells are exposed to apoCIII they undergo apoptosis, which can be prevented by... -
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- The Effects of Antidepressants on the Energy Metabolism in LETO Rat
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Jeon HT, Joe KH, Ahn YK, Kim HT, Kee BS
- KMID: 2011066
- Korean J Psychopharmacol.
- 2009 Jul;20(4):194-204.
Objectives : A diverse range of adverse effects has been linked to the application of antidepressants for the treatment of depressive disorder. Recently, evidence has been emerging of the adverse... -
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- Transcriptional Regulation of Pyruvate Dehydrogenase Kinase
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Jeong JY, Jeoung NH, Park KG, Lee IK
- KMID: 2174390
- Diabetes Metab J.
- 2012 Oct;36(5):328-335.
- doi: 10.4093/dmj.2012.36.5.328
The pyruvate dehydrogenase complex (PDC) activity is crucial to maintains blood glucose and ATP levels, which largely depends on the phosphorylation status by pyruvate dehydrogenase kinase (PDK) isoenzymes. Although it... -
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- Peroxisome Proliferator-Activated Receptor gammaActivation Promotes Adipogenesis in Human Mesenchymal Stem Cells
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Kim EJ, Kim SH, Kim YH, Kim SJ, Hahn SB, Lee JW
- KMID: 2023943
- J Korean Orthop Res Soc.
- 2003 Apr;6(1):127-134.
PURPOSE: In this study, we determined that the troglitazones could induce uniform adipogenesis of human mesenchymal stem cells (MSCs) within a short time in a dose- and a time-dependent manners.... -
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- Sex-specific regulation of immune responses by PPARs
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Park HJ, Choi JM
- KMID: 2389292
- Exp Mol Med.
- 2017 Aug;49(8):e364.
- doi: 10.1038/emm.2017.102
The prevalence of autoimmune, infectious and metabolic diseases is different for men and women owing to the respective ability of their immune systems to respond to self and foreign antigens.... -
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- Regulatory Effects of Fenofibrate with Inflammatory Response and Myocardiac Dysfunction in Lipopolysaccharide-stimulated Heart Tissues
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Song DH, Hwang Y, Yoo SJ
- KMID: 2333209
- J Korean Soc Emerg Med.
- 2012 Oct;23(5):721-729.
PURPOSE: This study was intended to establish experimental conditions for monitoring the cardioprotective effects of fenofibrate on cardiac function in lipopolysaccharide (LPS)-stimulated BalB/c mice. METHODS: To investigate the effects of fenofibrate... -
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- Role of COX-2 and PPAR in Gastric Carcinogenesis
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Yeo M, Hahm KB
- KMID: 1113299
- Korean J Gastroenterol.
- 2004 Jul;44(1):53-56.
No abstract available. -
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- Anti-inflammatory effects of PPARgamma on human dental pulp cells
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Kim JH
- KMID: 2175820
- J Korean Acad Conserv Dent.
- 2006 May;31(3):203-214.
- doi: 10.5395/JKACD.2006.31.3.203
Dental pulp is a loose, mesenchymal tissue almost entirely enclosed in the dentin. It consists of cells, ground substance, and neural and vascular supplies. Damage to the dental pulp by... -
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- Fenofibrate, a peroxisome proliferator-activated receptor alpha-agonist, blocks lipopolysaccharide-induced inflammatory pathways in mouse liver
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Won TW
- KMID: 1472524
- Korean J Hepatobiliary Pancreat Surg.
- 2013 Aug;17(3):89-108.
- doi: 10.14701/kjhbps.2013.17.3.89
BACKGROUNDS/AIMS: During the acute phase response, cytokines induce marked alterations in lipid metabolism including an increase in serum triglyceride levels and a decrease in hepatic fatty acid oxidation, in bile... -
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