- Independent Prognostic Value of the Fascin Expression in Patients with Esophageal Cancer
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Choi PJ, Jeong SS, Bang JH, Cho KJ, Woo JS, Roh MS
- KMID: 1987459
- Korean J Thorac Cardiovasc Surg.
- 2008 Feb;41(1):74-81.
Backgrond: Fascin is an actin-bundling protein that induces membrane protrusions and it increases cell motility in various transformed cells. Esophageal cancer is one of the most lethal malignancies, and it... -
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- Immunohistochemical detection of p53 protein, c-erbB-2 protein, epidermal growth factor receptor protein and proliferating cell nuclear antigen in gastric carcinoma
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Jang WI, Yang WI, Lee CI, Kim HS, Song KS, Cho MY, Park JK, Shim YH
- KMID: 2157514
- J Korean Med Sci.
- 1993 Aug;8(4):293-304.
- doi: 10.3346/jkms.1993.8.4.293
There is increasing evidence that genes involved in normal cell growth and differentiation (oncogenes) or genes that encode for growth factors are important in determining the development and biologic aggressiveness... -
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- The Prognostic Impact of Heat Shock Proteins Expression in Patients with Esophageal Cancer: A Meta-Analysis
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Wang XW, Shi XH, Tong YS, Cao XF
- KMID: 2345875
- Yonsei Med J.
- 2015 Nov;56(6):1497-1502.
- doi: 10.3349/ymj.2015.56.6.1497
PURPOSE: Heat shock proteins (HSPs) are highly conserved molecular chaperones. There are various studies that assess the prognostic value of HSPs in patients with esophageal cancer, but the conclusion remains... -
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- Primary Rectal Malignant Melanoma with Rapid Progression after Complete Resection
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Kim KO, Jang BI, Kim JH, Bae YK
- KMID: 1775895
- Korean J Gastroenterol.
- 2010 Mar;55(3):151-153.
- doi: 10.4166/kjg.2010.55.3.151
No abstract available. -
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- Anti-tumor mechanisms and regulation of survivin by selective cyclooxygenase-2 inhibitor
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Jang JW
- KMID: 1381460
- Korean J Hepatol.
- 2008 Sep;14(3):305-308.
- doi: 10.3350/kjhep.2008.14.3.305
No abstract available. -
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- Brain site-specific proteome changes in aging-related dementia
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Manavalan , Mishra M, Feng L, Sze SK, Akatsu H, Heese K
- KMID: 2154258
- Exp Mol Med.
- 2013 Sep;45(9):e39.
This study is aimed at gaining insights into the brain site-specific proteomic senescence signature while comparing physiologically aged brains with aging-related dementia brains (for example, Alzheimer's disease (AD)). Our study... -
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- Expression levels of heat shock protein 27 and cellular FLICE-like inhibitory protein in prostate cancer correlate with Gleason score sum and pathologic stage
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Lee SW, Cho JM, Cho HJ, Kang JY, Kim EK, Yoo TK
- KMID: 2160647
- Korean J Urol.
- 2015 Jul;56(7):505-514.
- doi: 10.4111/kju.2015.56.7.505
PURPOSE: Heat shock protein (HSP) 27 protects the cell by controlling apoptosis and immune reactions, and c-FLIP (cellular-FLICE inhibitory protein) inhibits apoptosis by inhibiting caspase-8 activity. We investigated the relationship... -
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- Expression of MAGE-1, -2, and -3 genes in gastric carcinomas and cancer cell lines derived from Korean patients
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Kim YM, Lee YH, Shin SH, Kim EH, Choi YW, Lee KM, Park JH, Lee YU, Seel DJ, Kim MC
- KMID: 1066496
- J Korean Med Sci.
- 2001 Feb;16(1):62-68.
- doi: 10.3346/jkms.2001.16.1.62
We investigated the expression of MAGE-1, -2, and -3 genes in tissues of 51 gastric carcinomas from Korean patients and in 11 gastric cancer cell lines established in Korea using... -
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- DNA mismatch repair-related protein loss as a prognostic factor in endometrial cancers
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Kato M, Takano M, Miyamoto M, Sasaki N, Goto T, Tsuda H, Furuya K
- KMID: 2158801
- J Gynecol Oncol.
- 2015 Jan;26(1):40-45.
- doi: 10.3802/jgo.2015.26.1.40
OBJECTIVE: Recent investigations have revealed DNA mismatch repair (MMR) gene mutations are closely related with carcinogenesis of endometrial cancer; however the impact of MMR protein expression on prognosis is not... -
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- Black rice anthocyanidins prevent retinal photochemical damage via involvement of the AP-1/NF-kappaB/Caspase-1 pathway in Sprague-Dawley Rats
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Jia H, Chen W, Yu X, Wu X, Li S, Liu H, Liao J, Liu W, Mi M, Liu L, Cheng D
- KMID: 1705566
- J Vet Sci.
- 2013 Sep;14(3):345-353.
- doi: 10.4142/jvs.2013.14.3.345
The effects of black rice anthocyanidins (BRACs) on retinal damage induced by photochemical stress are not well known. In the present study, Sprague-Dawley rats were fed AIN-93M for 1 week,... -
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- Activity of Matrix Metalloproteinase-2 and its Significance after Resection of Stage I Non-small Cell Lung Cancer
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Kim SH, Hong YS, Lee J, Son DS, Lim YS, Song IS, Lee HS, Kim DH, Kim J, Choi YS
- KMID: 2393756
- Korean J Thorac Cardiovasc Surg.
- 2005 Jan;38(1):38-43.
BACKGROUND: Matrix metalloproteinase-2 (MMP-2) is a class of proteolytic enzymes that digest collagen type IV and other components of the basement membrane. It plays a key role in the local... -
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- Clinicopathological Characteristics of Patients with Gastric Cancer according to the Expression of LIN28A
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Park CH, Lee JH, Lee NK, Lee YC, Lee SK
- KMID: 2412067
- Gut Liver.
- 2016 Sep;10(5):714-718.
- doi: 10.5009/gnl15283
BACKGROUND/AIMS: Although LIN28A is known to potentially play a role in the oncogenesis of various cancers, whether LIN28A expression is a predictor of poor prognosis in patients with gastric cancer... -
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- Is Immunohistochemistry for MLH1 and MSH2 Proteins a Useful Method for Detection of Microsatellite Instability in Sporadic Colorectal Cancer?
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Do JH, Chang SK, Ahnn JY, Cha BK, Cheong SM, Kim DW, Cheong HR, Kim HJ, Kim JG, Lee TJ, Park ES, Park SM
- KMID: 1112187
- Korean J Gastroenterol.
- 2003 Nov;42(5):369-376.
BACKGROUND/AIMS: In order to identify microsatellite instability (MSI), the test based on the polymerase chain reaction (PCR) can be used. However, PCR is not routinely performed in all hospital... -
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- The Proteomics Approach to Find Biomarkers in Gastric Cancer
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Ryu JW, Kim HJ, Lee YS, Myong NH, Hwang CH, Lee GS, Yom HC
- KMID: 648901
- J Korean Med Sci.
- 2003 Aug;18(4):505-509.
- doi: 10.3346/jkms.2003.18.4.505
Gastric cancer is a very serious disease and is naturally resistant to many anticancer drugs. To reduce the mortality and improve the effectiveness of therapy, many studies have tried to... -
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- Expression of cyclin-dependent kinase inhibitor p27kip1 in malignant lymphomas
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Oh YH, Park CK
- KMID: 1730635
- J Korean Med Sci.
- 2000 Aug;15(4):399-406.
- doi: 10.3346/jkms.2000.15.4.399
p27kip1 is a cyclin-dependent kinase inhibitor that regulates progression from G1 into S phase. Aberrations in cell cycle control are often observed in tumors d might even be necessary in... -
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- Clinicopathological Characteristics of Colorectal Cancer with Family History: an Evaluation of Family History as a Predictive Factor for Microsatellite Instability
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Park IJ, Kim HC, Yoon YS, Yu CS, Jang SJ, Kim JC
- KMID: 1785795
- J Korean Med Sci.
- 2007 Sep;22(Suppl):S91-S97.
- doi: 10.3346/jkms.2007.22.S.S91
To determine whether family history of cancer may be a risk factor for the mutator phenotype in colorectal cancer, we recruited 143 consecutive colorectal cancer patients with a family history... -
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- A Case of Hepatic Angiomyolipoma Mimicking Hepatocellular Carcinoma
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Sinn DH, Choi D, Choi MS, Park CK
- KMID: 782955
- Korean J Gastroenterol.
- 2008 Jan;51(1):1-3.
No abstract availble. -
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- Expressions of HSP70 and HSP27 in Hepatocellular Carcinoma
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Joo M, Chi JG, Lee H
- KMID: 1781767
- J Korean Med Sci.
- 2005 Oct;20(5):829-834.
- doi: 10.3346/jkms.2005.20.5.829
The heat shock proteins (HSPs) are ubiquitous molecules induced in cells exposed to various stress conditions, including carcinogenesis. The HSP70 and HSP27 among HSPs are of special relevance in human... -
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- Silencing of ABCG2 by MicroRNA-3163 Inhibits Multidrug Resistance in Retinoblastoma Cancer Stem Cells
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Jia M, Wei Z, Liu P, Zhao X
- KMID: 2373690
- J Korean Med Sci.
- 2016 Jun;31(6):836-842.
- doi: 10.3346/jkms.2016.31.6.836
To investigate the function and regulation mechanism of ATP-binding cassette, subfamily G, member 2 (ABCG2) in retinoblastoma cancer stem cells (RCSCs), a long-term culture of RCSCs from WERI-Rb1 cell line... -
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- 2,3,7,8-Tetrachlorodibenzo-P-Dioxin Induced Cell-Specific Drug Transporters With Acquired Cisplatin Resistance in Cisplatin Sensitive Cancer Cells
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Gotovdorj , Lee E, Lim Y, Cha EJ, Kwon D, Hong E, Kim Y, Oh MY
- KMID: 1794595
- J Korean Med Sci.
- 2014 Sep;29(9):1188-1198.
- doi: 10.3346/jkms.2014.29.9.1188
2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) can induce drug transporter genes such as the ATP-binding cassette G member 2 (ABCG2), which contributes to multidrug resistance. We investigated the effect of TCDD pretreatment on drug... -
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