Korean J Gastroenterol.  2010 Mar;55(3):151-153. 10.4166/kjg.2010.55.3.151.

Primary Rectal Malignant Melanoma with Rapid Progression after Complete Resection

• Kim KO
• Jang BI
• Kim JH
• Bae YK

• KMID: 1775895
• DOI: http://doi.org/10.4166/kjg.2010.55.3.151

Abstract

No abstract available.

MeSH Terms

Antigens, Neoplasm/metabolism
Bone Neoplasms/diagnosis/drug therapy/secondary
Disease Progression
Humans
Interferons/therapeutic use
Liver Neoplasms/diagnosis/drug therapy/secondary
Male
Melanoma/*diagnosis/pathology/surgery
Middle Aged
Neoplasm Proteins/metabolism
Positron-Emission Tomography
Rectal Neoplasms/*diagnosis/pathology/surgery
S100 Proteins/metabolism
Tamoxifen/therapeutic use
Tomography, X-Ray Computed

Figure

• 

  Fig. 1. Endoscopic finding of the polypoid mass. There was about 3 cm sized fungating mass at the rectum. At the top of the mass, slightly black colored base was noted.

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  Fig. 2. Preoperative radiologic findings. (A) At the rectum, about 3 cm sized fungating mass was noted. (B) There was one hepatic cyst, but no metastasis.

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  Fig. 3. Histologic findings after surgical resection. The tumor cells were spindle-shaped and formed fascicles at the upper portion of the polypoid mass (H&E, ×100). The tumor cells showed focal immunoreactivity for S-100 and HMB-45, which represented melanocytic differentiation (×100).

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  Fig. 4. Follow-up CT of 7 months after surgical resection. (A) There were multiple soft tissue masses with ascites at the pelvic cavity and residual perirectal space. (B) Intractable metastatic masses at both lobes of the liver were noted.

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