- CD24⺠Cell Depletion Permits Effective Enrichment of Thymic iNKT Cells While Preserving Their Subset Composition
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Park JY, Kwon J, Kim EY, Fink J, Kim HK, Park JH
- KMID: 2444162
- Immune Netw.
- 2019 Apr;19(2):e14.
- doi: 10.4110/in.2019.19.e14
Invariant NKT (iNKT) cells are a small subset of thymus-generated T cells that produce cytokines to control both innate and adaptive immunity. Because of their very low frequency in the... -
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- Lineage Differentiation Program of Invariant Natural Killer T Cells
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Kwon DI, Lee YJ
- KMID: 2400623
- Immune Netw.
- 2017 Dec;17(6):365-377.
- doi: 10.4110/in.2017.17.6.365
Invariant natural killer T (iNKT) cells are innate T cells restricted by CD1d molecules. They are positively selected in the thymic cortex and migrate to the medullary area, in which... -
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- Epstein-Barr Virus-Associated Vesiculopapular Eruption on the Face of a Patient with Natural Killer T Cell Lymphoma
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Lim JS, Kim TM, Cho KH
- KMID: 2388915
- Ann Dermatol.
- 2017 Oct;29(5):618-620.
- doi: 10.5021/ad.2017.29.5.618
Unlike typical hydroa vacciniforme (HV), Epstein-Barr virus (EBV)-associated HV-like eruption is more variable in its clinical manifestations. In some patients, progression to lymphoma or leukemia has been reported, which are... -
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- Unusual Suspects in the Development of Obesity-Induced Inflammation and Insulin Resistance: NK cells, iNKT cells, and ILCs
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Bonamichi , Lee J
- KMID: 2392464
- Diabetes Metab J.
- 2017 Aug;41(4):229-250.
- doi: 10.4093/dmj.2017.41.4.229
The notion that obesity-induced inflammation mediates the development of insulin resistance in animal models and humans has been gaining strong support. It has also been shown that immune cells in... -
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- Deficiencies of Circulating Mucosal-associated Invariant T Cells and Natural Killer T Cells in Patients with Multiple Trauma
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Jo YG, Choi HJ, Kim JC, Cho YN, Kang JH, Jin HM, Kee SJ, Park YW
- KMID: 2375074
- J Korean Med Sci.
- 2017 May;32(5):750-756.
- doi: 10.3346/jkms.2017.32.5.750
Mucosal-associated invariant T (MAIT) cells and natural killer T (NKT) cells are known to play important roles in autoimmunity, infectious diseases and cancers. However, little is known about the roles... -
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- Flagellin Modulates the Function of Invariant NKT Cells From Patients With Asthma via Dendritic Cells
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Shim JU, Rhee JH, Jeong JU, Koh YI
- KMID: 2391040
- Allergy Asthma Immunol Res.
- 2016 May;8(3):206-215.
- doi: 10.4168/aair.2016.8.3.206
PURPOSE: Invariant natural killer T (iNKT) cells play a critical role in the pathogenesis of asthma. We previously reported the association between circulating Th2-like iNKT cells and lung function in... -
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- Increased Th2-like Invariant Natural Killer T cells in Peripheral Blood From Patients With Asthma
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Shim JU, Koh YI
- KMID: 2181081
- Allergy Asthma Immunol Res.
- 2014 Sep;6(5):444-448.
- doi: 10.4168/aair.2014.6.5.444
PURPOSE: Invariant natural killer T (iNKT) cells might play an important role in asthma pathogenesis in humans. Our previous study found no difference in the number of blood iNKT cells... -
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- B Cells Promote Th1- Skewed NKT Cell Response by CD1d-TCR Interaction
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Shin JH, Park SH
- KMID: 1493617
- Immune Netw.
- 2013 Oct;13(5):218-221.
- doi: 10.4110/in.2013.13.5.218
CD1d expressing dendritic cells (DCs) are good glyco-lipid antigen presenting cells for NKT cells. However, resting B cells are very weak stimulators for NKT cells. Although alpha-galactosylceramide (alpha-GalCer) loaded B... -
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- Natural Killer T Cells in Acute and Unmedicated Patients with Major Depressive Disorder
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Park EJ, Lee JH, Lee KH, Han SI, Jeon YW
- KMID: 2341176
- J Korean Neuropsychiatr Assoc.
- 2006 May;45(3):208-213.
OBJECTIVES: To evaluate an association between depression and altered immunity, we examined peripheral T lymphocyte or natural killer (NK) cell measures plasma ACTH and cortisol using the flow cytometry in... -
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- The study on cytotoxicity of cytokines produced by the activated human NKT cells on neuroblastoma
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Cho JY, Yoon YW, Yoon HS, Kim JD, Choi DY
- KMID: 2140911
- Korean J Pediatr.
- 2006 Apr;49(4):439-445.
- doi: 10.3345/kjp.2006.49.4.439
PURPOSE: alpha-Galactosylceramide (alpha-GalCer)-stimulated human Valpha24 natural killer T (NKT) cells exert antitumor activity against some leukemia in a CD1d dependent and TCR-mediated manner, but could not kill CD1d-negative neuroblastoma (NB)... -
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- A Case of Natural Killer T-cell Lymphoma of the Tongue
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Cho SG, Lee DH, Kim HR, Cho KJ
- KMID: 2276199
- Korean J Otolaryngol-Head Neck Surg.
- 2004 Aug;47(8):783-786.
Malignant lymphoma, which represents about 5.4% of all neoplasms and more significantly 19-28% of malignant neoplasms, is the most common non-epithelial malignancy in the head and neck area and non-Hodgkin's... -
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- Changes of Natural Killer T Cells in Behcet's Uveitis
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Ahn JK, Yu HG, Kim YJ, Kim SJ, Yu YS, Chung H
- KMID: 2206814
- J Korean Ophthalmol Soc.
- 2004 Aug;45(8):1356-1362.
PURPOSE: To determine the phenotypic and functional changes of circulating CD56+ T cells in ocular Behcet's disease (BD) according to the intraocular inflammatory activity METHODS: Forty patients with BD were... -
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- T Cell Receptor Rearrangement in NKT Cells Differentiated from Cord Blood CD34+ Cells
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Jung YJ, Woo SY
- KMID: 2352866
- Ewha Med J.
- 2003 Jun;26(2):137-142.
- doi: 10.12771/emj.2003.26.2.137
OBJECTIVES: To investigate the time of rearrangement of the TCR gene in the process of NKT cell differentiation from CD34+ human cord blood cells in vitro. METHODS: We isolated the CD34+... -
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- The Development of NKT Cells in Thymus is Defective in CD45 Knockout Mice
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Jung DH, Margulies
- KMID: 1573065
- Korean J Immunol.
- 2000 Sep;22(3):117-121.
No abstract available. -
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