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Is There True Gender Difference of Irritable Bowel Syndrome in Asia?: Author's Reply

Makharia G

  • KMID: 2326224
  • J Neurogastroenterol Motil.
  • 2011 Apr;17(2):208-208.
No abstract available.
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Correlation of fecal calprotectin and patient-reported outcome measures in patients with ulcerative colitis

Kamat N, Vuyyuru SK, Kedia S, Sahu P, Kante B, Kumar P, Ranjan MK, Singh MK, Kumar S, Sachdev V, Makharia G, Ahuja V

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Techniques of Functional and Motility Test: How to Perform and Interpret Intestinal Permeability

Mishra A, Makharia G

  • KMID: 2325955
  • J Neurogastroenterol Motil.
  • 2012 Oct;18(4):443-447.
Transport of molecules across the intestinal epithelium takes place through 2 major routes, ie, trans-cellular and paracellular. Assessment of intestinal permeability is performed to assess the overall function of transport...
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Transfer Dysphagia Due to Focal Dystonia

Samal P, Goyal V, Makharia G, Das CJ, Gorthi SP, VY V, Singh MB, Srivastava MVP

OBJECTIVE: The inability to propel a bolus of food successfully from the posterior part of the oral cavity to the oropharynx is defined as transfer dysphagia. The present case series...
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Familial aggregation of inflammatory bowel disease in patients with ulcerative colitis

Gupta A, Bopanna S, Kedia S, Yadav DP, Goyal S, Jain S, Makharia G, Ahuja V

BACKGROUND/AIMS: Familial occurrence of inflammatory bowel disease (IBD) is well documented. Reports from Western countries have shown a higher familial occurrence of ulcerative colitis (UC) in first- and second-degree relatives...
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Are Truelove and Witts criteria for diagnosing acute severe colitis relevant for the Indian population? A prospective study

Jain S, Kedia S, Bopanna S, Yadav DP, Goyal S, Sahni P, Pal S, Dash NR, Makharia G, Travis SP, Ahuja V

BACKGROUND/AIMS: Truelove and Witts criteria have been used to define acute severe colitis since the 1950s. However, hemoglobin (an additional criterion of the definition) levels in the general population in...
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Prevalence of Irritable Bowel Syndrome: A Community Based Study From Northern India

Makharia G, Verma AK, Amarchand , Goswami A, Singh P, Agnihotri , Suhail F, Krishnan A

  • KMID: 2326193
  • J Neurogastroenterol Motil.
  • 2011 Jan;17(1):82-87.
BACKGROUND/AIMS: The prevalence of irritable bowel syndrome (IBS) varies from 4% to 20% in different Asian nations. Prevalence of IBS in native North Indian community is not known. METHODS: Between November...
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Prospective validation of CD4+CD25+FOXP3+ T-regulatory cells as an immunological marker to differentiate intestinal tuberculosis from Crohn’s disease

Rampal R, Kedia S, Wari MN, Madhu D, Singh AK, Tiwari V, Mouli VP, Mohta S, Makharia G, Ahuja V

Background/Aims: Crohn’s disease (CD) and intestinal tuberculosis (ITB) remain “difficult-to-differentiate” diseases. We have previously documented peripheral blood frequency of CD4+CD25+FOXP3+ T-regulatory cells (Treg) as a biomarker to differentiate CD and...
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Efficacy and tolerability of hyperbaric oxygen therapy in small bowel stricturing Crohn’s disease: a pilot study

Kante B, Sahu P, Kedia S, Vuyyuru SK, Soni K, Singhal M, Sharma R, Makharia G, Ahuja V

Background/Aims: Existing therapeutic options for complicated Crohn’s disease (CD) like biologics and surgery are limited by inadequate long-term efficacy, cost, and adverse effects. Tissue hypoxia is important in CD pathogenesis...
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A simple phenotypic classification for celiac disease

Sood A, Midha V, Makharia G, Thelma BK, Halli SS, Mehta V, Mahajan R, Narang V, Sood K, Kaur K

BACKGROUND/AIMS: Celiac disease is a global health problem. The presentation of celiac disease has unfolded over years and it is now known that it can manifest at different ages, has...
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Interferon-gamma release assay has poor diagnostic accuracy in differentiating intestinal tuberculosis from Crohn’s disease in tuberculosis endemic areas

Sachdeva K, Kumar P, Kante B, Vuyyuru SK, Mohta S, Ranjan MK, Singh MK, Verma M, Makharia G, Kedia S, Ahuja V

Background/Aims: Intestinal tuberculosis (ITB) and Crohn’s disease (CD) frequently present with a diagnostic dilemma because of similar presentation. Interferon-gamma release assay (IGRA) has been used in differentiating ITB from CD,...
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Evaluation of Xpert MTB/RIF assay performance in the diagnosis of abdominal tuberculosis

Kumar S, Bopanna S, Kedia S, Mouli P, Dhingra R, Padhan R, Kohli M, Chaubey J, Sharma R, Das P, Dattagupta S, Makharia G, Sharma S, Ahuja V

BACKGROUND/AIMS: The use of genetic probes for the diagnosis of pulmonary tuberculosis (TB) has been well described. However, the role of these assays in the diagnosis of intestinal tuberculosis is...
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Addition of computed tomography chest increases the diagnosis rate in patients with suspected intestinal tuberculosis

Kedia S, Sharma R, Vuyyuru SK, Madhu D, Sahu P, Kante B, Das P, Goyal A, Madan K, Makharia G, Ahuja V

Background/Aims: Intestinal tuberculosis (ITB) is difficult to diagnose due to poor sensitivity of definitive diagnostic tests. ITB may be associated with concomitant pulmonary tuberculosis (PTB) which may remain undetected on...
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Psychiatric, Somatic and Other Functional Gastrointestinal Disorders in Patients With Irritable Bowel Syndrome at a Tertiary Care Center

Singh P, Agnihotri , Pathak MK, Shirazi A, Tiwari RP, Sreenivas , Sagar R, Makharia G

  • KMID: 2325932
  • J Neurogastroenterol Motil.
  • 2012 Jul;18(3):324-331.
BACKGROUND/AIMS: To study the prevalence of somatic and psychiatric co-morbidities in the patients of irritable bowel syndrome (IBS) and to assess the quality of life (QOL) of these patients. METHODS: One...
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Prevalence of hepatitis B, hepatitis C and human immunodeficiency viral infections in patients with inflammatory bowel disease in north India

Harsh P, Gupta V, Kedia S, Bopanna S, Pilli S, Surendernath , Makharia G, Ahuja V

BACKGROUND/AIMS: Patients with inflammatory bowel disease (IBD) often require immunosuppressive therapy and blood transfusions and therefore are at a high risk of contracting infections due to hepatitis B (HBV) and...
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Role of random biopsies in surveillance of dysplasia in ulcerative colitis patients with high risk of colorectal cancer

Bopanna S, Roy M, Das P, Dattagupta S, Sreenivas , Mouli VP, Kedia S, Dhingra R, Pradhan R, Kumar NS, Yadav DP, Makharia G, Ahuja V

BACKGROUND/AIMS: Recent data suggest that the incidence of ulcerative colitis (UC) related colorectal cancer (CRC) in India is similar to that of West. The optimum method for surveillance is still...
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Efficacy and tolerability of exclusive enteral nutrition in adult patients with complicated Crohn’s disease

Sharma S, Gupta A, Kedia S, Agarwal S, Singh N, Goyal S, Jain S, Gupta V, Sahu P, Vuyyuru SK, Kante B, Sharma R, Panwar R, Sahni P, Makharia G, Ahuja V

Background/Aims: Exclusive enteral nutrition (EEN), an established modality for pediatric Crohn’s disease (CD) is seldomly utilized in adults. The present study reports the outcome of EEN in adult CD patients...
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High risk of tuberculosis during infliximab therapy despite tuberculosis screening in inflammatory bowel disease patients in India

Agarwal A, Kedia S, Jain S, Gupta V, Bopanna S, Yadav DP, Goyal S, Mouli VP, Dhingra R, Makharia G, Ahuja V

BACKGROUND/AIMS: The data on the risk of tuberculosis (TB) reactivation with infliximab (IFX) in patients with inflammatory bowel disease (IBD) from TB endemic countries, like India, is limited. The risk...
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Quantitative histology-based classification system for assessment of the intestinal mucosal histological changes in patients with celiac disease

Das P, Gahlot GP, Singh A, Baloda V, Rawat R, Verma AK, Khanna G, Roy M, George A, Singh A, Nalwa A, Ramteke P, Yadav R, Ahuja V, Sreenivas , Gupta SD, Makharia G

BACKGROUND/AIMS: The existing histological classifications for the interpretation of small intestinal biopsies are based on qualitative parameters with high intraobserver and interobserver variations. We have developed and propose a quantitative...
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Use of thiopurines in inflammatory bowel disease: an update

Singh A, Mahajan R, Kedia S, Dutta AK, Anand A, Bernstein CN, Desai D, Pai CG, Makharia G, Tevethia HV, Mak JW, Kaur K, Peddi K, Ranjan MK, Arkkila P, Kochhar R, Banerjee R, Sinha SK, Ng SC, Hanauer S, Verma S, Dutta U, Midha V, Mehta V, Ahuja V, Sood A

Inflammatory bowel disease (IBD), once considered a disease of the Western hemisphere, has emerged as a global disease. As the disease prevalence is on a steady rise, management of IBD...
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