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Cerebral Amyloid Angiopathy: An Undeniable Small Vessel Disease

Wang L, Liu Q, Yue D, Liu J, Fu Y

Cerebral amyloid angiopathy (CAA) has been proven to be the most common pathological change in cerebral small vessel disease except arteriosclerosis. In recent years, with the discovery of imaging technology...
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Fasting Blood Glucose, Cholesterol, and Risk of Primary Liver Cancer: The Kailuan Study

Ma X, Cui H, Sun M, Liu Q, Liu X, Li G, Wei Y, Fu Q, Liu S, Cao L

Purpose The influence of fasting blood glucose (FBG) and cholesterolemia primary liver cancer (PLC) in china was analyzed via a large prospective cohort study based on a community population, and the...
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Noninvasive Imaging for the Evaluation of Non-Alcoholic Fatty Liver Disease Spectrum

Liu Q, Nie H, Xu H, Wang P, Lei P

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Identification of determinants that mediate binding between Tembusu virus and the cellular receptor heat shock protein A9

Zhao D, Liu Q, Huang X, Wang H, Han K, Yang J, Bi K, Liu Y, Zhang L, Li Y

Heat shock protein A9 (HSPA9), a member of the heat shock protein family, is a putative receptor for Tembusu virus (TMUV). By using Western blot and co-immunoprecipitation assays, E protein...
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Clinicopathologic Characteristics and Prognosis of Tongue Squamous Cell Carcinoma in Patients with and without a History of Radiation for Nasopharyngeal Carcinoma: A Matched Case-Control Study

Zhang P, Zhang L, Liu H, Zhao L, Li Y, Shen JX, Liu Q, Liu MZ, Xi M

PURPOSE: Previous studies reported an association between an increased risk of tongue cancer and radiation treatment for nasopharyngeal carcinoma (NPC). This study compared the clinicopathologic characteristics and outcomes of tongue...
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Sterculic Acid and Its Analogues Are Potent Inhibitors of Toxoplasma gondii

Hao P, Alaraj IQ, Al Dulayymi JR, Baird MS, Liu J, Liu Q

Toxoplasmosis is a serious disease caused by Toxoplasma gondii, one of the most widespread parasites in the world. Lipid metabolism is important in the intracellular stage of T. gondii. Stearoyl-CoA...
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Glutamic Acid Decarboxylase Autoantibody Detection by Electrochemiluminescence Assay Identifies Latent Autoimmune Diabetes in Adults with Poor Islet Function

Zhu Y, Qian L, Liu Q, Zou J, Zhou Y, Yang T, Huang G, Zhou Z, Liu Y

Background: The detection of glutamic acid decarboxylase 65 (GAD65) autoantibodies is essential for the prediction and diagnosis of latent autoimmune diabetes in adults (LADA). The aim of the current study...
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LncRNA MEG3 Regulates Imatinib Resistance in Chronic Myeloid Leukemia via Suppressing MicroRNA-21

Zhou X, Yuan P, Liu Q, Liu Z

Imatinib resistance has become a major clinical problem for chronic myeloid leukemia. The aim of the present study was to investigate the involvement of MEG3, a lncRNA, in imatinib resistance...
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Production and immunogenicity of chimeric virus-like particles containing the spike glycoprotein of infectious bronchitis virus

Lv L, Li X, Liu G, Li R, Liu Q, Shen H, Wang W, Xue C, Cao Y

Infectious bronchitis virus (IBV) poses a severe threat to the poultry industry and causes heavy economic losses worldwide. Vaccination is the most effective method of preventing infection and controlling the...
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Hair Growth Promoting Effects of 650 nm Red Light Stimulation on Human Hair Follicles and Study of Its Mechanisms via RNA Sequencing Transcriptome Analysis

Yang K, Tang Y, Ma Y, Liu Q, Huang Y, Zhang Y, Shi X, Zhang L, Zhang Y, Wang J, Zhu Y, Liu W, Tan Y, Lin J, Wu W

Background: Androgenetic alopecia (AGA) leads to thinning of scalp hair and affects 60%~70% of the adult population worldwide. Developing more effective treatments and studying its mechanism are of great significance....
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Melatonin Attenuates Mitochondrial Damage in Aristolochic AcidInduced Acute Kidney Injury

Sun J, Pan J, Liu Q, Cheng J, Tang Q, Ji Y, Cheng K, wang R, Liu L, Wang D, Wu N, Zheng X, Li J, Zhang X, Zhu Z, Ding Y, Zheng F, Li J, Zhang Y, Yuan Y

Aristolochic acid (AA), extracted from Aristolochiaceae plants, plays an essential role in traditional herbal medicines and is used for different diseases. However, AA has been found to be nephrotoxic and...
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Fumigaclavine C attenuates adipogenesis in 3T3-L1 adipocytes and ameliorates lipid accumulation in high-fat diet-induced obese mice

Yu WG, He Y, Chen YF, Gao XY, Ning WE, Liu CY, Tang TF, Liu Q, Huang XC

Fumigaclavine C (FC), an active indole alkaloid, is obtained from endophytic Aspergillus terreus (strain No. FC118) by the root of Rhizophora stylosa (Rhizophoraceae). This study is designed to evaluate whether...
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Differential Profile of Plasma Circular RNAs in Type 1 Diabetes Mellitus

Li Y, Zhou Y, Zhao M, Zou J, Zhu Y, Yuan X, Liu Q, Cai H, Chu CQ, Liu Y

Background No currently available biomarkers or treatment regimens fully meet therapeutic needs of type 1 diabetes mellitus (T1DM). Circular RNA (circRNA) is a recently identified class of stable noncoding RNA that...
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Overview of fuzuloparib in the treatment of ovarian cancer: background and future perspective

Li N, Liu Q, Tian Y, Wu L

Over the last decade, clinical trials using various poly ADP ribose polymerase (PARP) inhibitors on patients with ovarian cancer have shown promising results. The introduction of PARP inhibitors has changed...
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A Comparative Study of Unsupervised Deep Learning Methods for MRI Reconstruction

He Z, Quan C, Wang S, Zhu Y, Zhang M, Zhu Y, Liu Q

Recently, unsupervised deep learning methods have shown great potential in image processing. Compared with a large-amount demand for paired training data of supervised methods with a specific task, unsupervised methods...
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Nano-BTA: A New Strategy for Intravesical Delivery of Botulinum Toxin A

Liu Q, Liao L

Botulinum neurotoxin subtype A (BoNT-A) has been part of the urology treatment arsenal since it was first used in the treatment of detrusor-sphincter dyssynergia more than 30 years ago. BoNT-A...
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Mannose Attenuates Colitis-Associated Colorectal Tumorigenesis by Targeting Tumor-Associated Macrophages

Liu Q, Li X, Zhang H, Li H

Mannose has recently drawn extensive attention for its substantial anti-cancer activities, but the underlying mechanism remains largely unclear. The aim of this study was to investigate the effects of mannose...
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Pharmacokinetics/Pharmacodynamics models of veterinary antimicrobial agents

Luo W, Chen D, Wu M, Li Z, Tao Y, Liu Q, Pan Y, Qu W, Yuan Z, Xie S

Misuse and abuse of veterinary antimicrobial agents have led to an alarming increase in bacterial resistance, clinical treatment failure, and drug residues. To address these problems, consistent and appropriate dosage...
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Prevalence and Subtypes of Blastocystis in Alpacas, Vicugna pacos in Shanxi Province, China

Ma YT, Liu Q, Xie SC, Li XD, Ma YY, Li TS, Gao WW, Zhu XQ

Blastocystis, an enteric protist, has been reported to be an important cause of protozoal gastrointestinal manifestations in humans and animals worldwide. Animals harboring certain Blastocystis subtypes (STs) may serve as...
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Risk factors affecting postoperative pulmonary function in congenital diaphragmatic hernia

Wang Q, Liu Q, Zang J, Wang J, Chen J

Purpose: It is well known that congenital diaphragmatic hernia (CDH) in infants impacts pulmonary function rehabilitation after surgery. However, the risk factors of postoperative pulmonary function are still unclear. In...
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