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Melatonin Attenuates Mitochondrial Damage in Aristolochic AcidInduced Acute Kidney Injury

Sun J, Pan J, Liu Q, Cheng J, Tang Q, Ji Y, Cheng K, wang R, Liu L, Wang D, Wu N, Zheng X, Li J, Zhang X, Zhu Z, Ding Y, Zheng F, Li J, Zhang Y, Yuan Y

Aristolochic acid (AA), extracted from Aristolochiaceae plants, plays an essential role in traditional herbal medicines and is used for different diseases. However, AA has been found to be nephrotoxic and...
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Effects of Intravesical Electrical Stimulation on Urinary Adenosine Triphosphate and Nitric Oxide in Rats With Detrusor Underactivity Induced By Bilateral Pelvic Nerve Crush Injury: The Possible Underlying Mechanism

Deng H, Liao L, Li X, Liu Q, Wang X, Zhou Z

Purpose: To explore the effect of intravesical electrical stimulation (IVES) on urinary adenosine triphosphate (ATP) and nitric oxide (NO) in rats with detrusor underactivity (DU) induced by bilateral pelvic nerve...
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Overview of fuzuloparib in the treatment of ovarian cancer: background and future perspective

Li N, Liu Q, Tian Y, Wu L

Over the last decade, clinical trials using various poly ADP ribose polymerase (PARP) inhibitors on patients with ovarian cancer have shown promising results. The introduction of PARP inhibitors has changed...
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Nano-BTA: A New Strategy for Intravesical Delivery of Botulinum Toxin A

Liu Q, Liao L

Botulinum neurotoxin subtype A (BoNT-A) has been part of the urology treatment arsenal since it was first used in the treatment of detrusor-sphincter dyssynergia more than 30 years ago. BoNT-A...
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Mannose Attenuates Colitis-Associated Colorectal Tumorigenesis by Targeting Tumor-Associated Macrophages

Liu Q, Li X, Zhang H, Li H

Mannose has recently drawn extensive attention for its substantial anti-cancer activities, but the underlying mechanism remains largely unclear. The aim of this study was to investigate the effects of mannose...
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Hair Growth Promoting Effects of 650 nm Red Light Stimulation on Human Hair Follicles and Study of Its Mechanisms via RNA Sequencing Transcriptome Analysis

Yang K, Tang Y, Ma Y, Liu Q, Huang Y, Zhang Y, Shi X, Zhang L, Zhang Y, Wang J, Zhu Y, Liu W, Tan Y, Lin J, Wu W

Background: Androgenetic alopecia (AGA) leads to thinning of scalp hair and affects 60%~70% of the adult population worldwide. Developing more effective treatments and studying its mechanism are of great significance....
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Fasting Blood Glucose, Cholesterol, and Risk of Primary Liver Cancer: The Kailuan Study

Ma X, Cui H, Sun M, Liu Q, Liu X, Li G, Wei Y, Fu Q, Liu S, Cao L

Purpose The influence of fasting blood glucose (FBG) and cholesterolemia primary liver cancer (PLC) in china was analyzed via a large prospective cohort study based on a community population, and the...
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The Pattern of Time to Onset and Resolution of Immune-Related Adverse Events Caused by Immune Checkpoint Inhibitors in Cancer: A Pooled Analysis of 23 Clinical Trials and 8,436 Patients

Tang SQ, Tang LL, Mao YP, Li WF, Chen L, Zhang Y, Guo Y, Liu Q, Sun Y, Xu C, Ma J

Purpose The occurrence pattern of immune-related adverse events (irAEs) induced by immune checkpoint inhibitor (ICI) in cancer treatment remains unclear. Materials and Methods Phase II-III clinical trials that evaluated ICI-based...
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Noninvasive Imaging for the Evaluation of Non-Alcoholic Fatty Liver Disease Spectrum

Liu Q, Nie H, Xu H, Wang P, Lei P

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A Comparative Study of Unsupervised Deep Learning Methods for MRI Reconstruction

He Z, Quan C, Wang S, Zhu Y, Zhang M, Zhu Y, Liu Q

Recently, unsupervised deep learning methods have shown great potential in image processing. Compared with a large-amount demand for paired training data of supervised methods with a specific task, unsupervised methods...
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Differential Profile of Plasma Circular RNAs in Type 1 Diabetes Mellitus

Li Y, Zhou Y, Zhao M, Zou J, Zhu Y, Yuan X, Liu Q, Cai H, Chu CQ, Liu Y

Background No currently available biomarkers or treatment regimens fully meet therapeutic needs of type 1 diabetes mellitus (T1DM). Circular RNA (circRNA) is a recently identified class of stable noncoding RNA that...
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Glutamic Acid Decarboxylase Autoantibody Detection by Electrochemiluminescence Assay Identifies Latent Autoimmune Diabetes in Adults with Poor Islet Function

Zhu Y, Qian L, Liu Q, Zou J, Zhou Y, Yang T, Huang G, Zhou Z, Liu Y

Background: The detection of glutamic acid decarboxylase 65 (GAD65) autoantibodies is essential for the prediction and diagnosis of latent autoimmune diabetes in adults (LADA). The aim of the current study...
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Prevalence and Subtypes of Blastocystis in Alpacas, Vicugna pacos in Shanxi Province, China

Ma YT, Liu Q, Xie SC, Li XD, Ma YY, Li TS, Gao WW, Zhu XQ

Blastocystis, an enteric protist, has been reported to be an important cause of protozoal gastrointestinal manifestations in humans and animals worldwide. Animals harboring certain Blastocystis subtypes (STs) may serve as...
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Risk factors affecting postoperative pulmonary function in congenital diaphragmatic hernia

Wang Q, Liu Q, Zang J, Wang J, Chen J

Purpose: It is well known that congenital diaphragmatic hernia (CDH) in infants impacts pulmonary function rehabilitation after surgery. However, the risk factors of postoperative pulmonary function are still unclear. In...
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Pharmacokinetics/Pharmacodynamics models of veterinary antimicrobial agents

Luo W, Chen D, Wu M, Li Z, Tao Y, Liu Q, Pan Y, Qu W, Yuan Z, Xie S

Misuse and abuse of veterinary antimicrobial agents have led to an alarming increase in bacterial resistance, clinical treatment failure, and drug residues. To address these problems, consistent and appropriate dosage...
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Patient and Care Delays of Breast Cancer in China

Li YL, Qin YC, Tang LY, Liao YH, Zhang W, Xie XM, Liu Q, Lin Y, Ren ZF

PURPOSE: This study differentiates patient and care delays of breast cancer and explores the related factors as well as the associations with the prognosis in Guangzhou, a southern city of...
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Dose-Dense Rituximab-CHOP versus Standard Rituximab-CHOP in Newly Diagnosed Chinese Patients with Diffuse Large B-Cell Lymphoma: A Randomized, Multicenter, Open-Label Phase 3 Trial

Li X, Huang H, Xu B, Guo H, Lin Y, Ye S, Yi J, Li W, Wu X, Wang W, Zhan H, Xie D, Peng J, Cao Y, Pu X, Guo C, Hong H, Wang Z, Fang X, Zhou Y, Lin S, Liu Q, Lin T

PURPOSE: Rituximab with cyclophosphamide, doxorubicin, vincristine, and prednisone administered every 3 weeks (R-CHOP-21) is the standard care for diffuse large B-cell lymphoma (DLBCL). It is unknown whether the dose-dense R-CHOP...
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Fumigaclavine C attenuates adipogenesis in 3T3-L1 adipocytes and ameliorates lipid accumulation in high-fat diet-induced obese mice

Yu WG, He Y, Chen YF, Gao XY, Ning WE, Liu CY, Tang TF, Liu Q, Huang XC

Fumigaclavine C (FC), an active indole alkaloid, is obtained from endophytic Aspergillus terreus (strain No. FC118) by the root of Rhizophora stylosa (Rhizophoraceae). This study is designed to evaluate whether...
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Identification of determinants that mediate binding between Tembusu virus and the cellular receptor heat shock protein A9

Zhao D, Liu Q, Huang X, Wang H, Han K, Yang J, Bi K, Liu Y, Zhang L, Li Y

Heat shock protein A9 (HSPA9), a member of the heat shock protein family, is a putative receptor for Tembusu virus (TMUV). By using Western blot and co-immunoprecipitation assays, E protein...
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Optimization of Extraction Condition of Methyl Jasmonate-treated Wild Ginseng Adventitious Root Cultures using Response Surface Methodology

Liu Q, Jo YH, Ahn JH, Kim SB, Paek KY, Hwang BY, Park SY, Lee MK

The usage of wild ginseng (Panax ginseng C.A. Meyer) has been limited due to short supply and high price. Therefore, sufficient production as well as efficient extraction of mountain ginseng...
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