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Pharmacokinetics of enrofloxacin HCl-2Hâ‚‚O (Enro-C) in dogs and pharmacokinetic/pharmacodynamic Monte Carlo simulations against Leptospira spp.

Sumano H, Ocampo L, Tapia G, Mendoza CD, Gutierrez

Pharmacokinetic/pharmacodynamic (PK/PD) ratios of reference enrofloxacin (Enro-R) and enrofloxacin as HCl-2H₂O (Enro-C), as well as Monte Carlo simulations based on composite MIC₅₀ and MIC₉₀ (MIC, minimum inhibitory concentration) vs. Leptospira...
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Evaluation of a Commercial Immuno-Chromatographic Assay Kit for Rapid Detection of IgM Antibodies against Leptospira Antigen in Human Serum

Amran F, Liow YL, Halim NA

Leptospirosis is a febrile zoonotic disease. Routine diagnosis of leptospirosis is based on the detection of specific antibodies with serological tests. The aim of our study was to determine the...
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Evaluation of safety and immunogenicity of a new octavalent inactivated vaccine containing porcine parvovirus, erysipelas, and leptospira

Kim K, Choi JY, Park SJ, Hahn TW

Porcine parvovirus, Erysipelothrix (E.) rhusiopathiae, and Leptospira (L.) interrogans are considered major etiologic agents of reproductive failure in pigs, causing economic loss in the swine industry. In this study, the...
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Identification of Leptospira species of Korean Isolates using Phylogenetic Analysis of Polymerase Chain Reaction-amplified 16S rDNA and LipL32 Genes

Park KH, Choi YJ, Shin SH, Choi MK, Kim YW, Jang WJ

In this study, we selected only serologically identified 15 Leptosira interrogans isolates in the past and analyzed and identified them by using molecular method. The partial 16S rDNA and LipL32...
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Characterization of Korean Leptospira interrogans Isolates by Pulsed-Field Gel Electrophoresis of Not I Digests of DNA

Yim EK, Chang IA, Lee JS, Kim YW, Woo SD, Ahn JY, Park SK, Cho MK

  • KMID: 2170093
  • Infect Chemother.
  • 2004 Apr;36(2):59-67.
BACKGROUND: Many strains of Leptospira interrogans have been isolated in Korea since 1984. Most isolates were identified as serovar lai by serological methods. The pulsed field gel electrophoresis (PFGE) patterns...
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A Prospective Multicenter Study of the Etiological Analysis in Adults with Community-Acquired Pneumonia: Legionella, Leptospira, Hantaan virus and Orientia tsutsugamushi

Kim MJ, Cheong HJ, Sohn JW, Shim HS, Park DW, Park SC, Woo JH, Kang JM, Kim YK, Shin WS, Kim YR, Lee HJ, Kim JH

  • KMID: 1599896
  • Korean J Infect Dis.
  • 2001 Feb;33(1):24-31.
BACKGROUND: Despite rigorous investigations, the etiology of community-acquired pneumonia remains unknown in about 50% of hospitalized patients. The diagnosis of the etiological agent is becoming more challenging and more critical...
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Prevalence of Leptospira interrogans in Wild Rodents in Korea

Cho MH, Kee SH, Kim YJ, Kim YW, Song HJ, Song KJ, Kim HH, Oh HB

  • KMID: 2099319
  • J Korean Soc Microbiol.
  • 1999 Dec;34(6):591-594.
Leptospirosis has been known as endemic disease in Korea since 1984. Wild rodent, mostly Apodemus agrarius, has been known as an important source of leptospiral infection especially in rainy circumstances...
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Serovar Identification and Genetic Characterization of Leptospira Isolates by Arbitrarily Primed PCR and Ribotyping

Chang WH, Kim YW, Oh HB, Cho MK, Kee SH, Kim HJ

  • KMID: 2146902
  • J Korean Soc Microbiol.
  • 1999 Aug;34(4):409-421.
Serovars of 22 leptospiral field isolates from rats trapped in Korea were identified by cross-agglutinin absorption test (CAAT). Genomic characteristics of 7 selected isolates and 6 antigenically closely related reference...
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Effects of Addition of Sugars on the Stability of Leptospira Vaccine

Seong I

  • KMID: 2082914
  • Korean J Infect Dis.
  • 1998 Dec;30(6):551-557.
BACKGROUND: Most of the current licensed viral and bacterial vaccines produced in the world are in the state of antigen suspension, and the immunogenicities of the vaccines can be maintained...
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Cloning, Overexpression and Purification of the Heat Shock Protein Hsp58, a Common Antigen of Leptospira Species

Kim MJ, Park SC, Park SH, Ahn BY

  • KMID: 1889989
  • Korean J Infect Dis.
  • 1998 Aug;30(4):332-341.
BACKGROUND: Humoral immune response is essential for resistance against leptospirosis, and the antigens in-volved in the response might be responsible for pathoge-nesis, diagnosis or immunity. The aim of this study...
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Study on antigenic analysis and serial antibody titration by using leptospira interrogans isolated at Chungchongbukdo

Park KH, Hong SC, Chang WH

  • KMID: 1687909
  • J Korean Soc Microbiol.
  • 1991 Aug;26(4):317-327.
No abstract available.
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Identification of new serovar yeonchon and hongchon belonging to leptospira interrogans icterohaemorrhagiae serogroup

Oh HB, Chang WH, Cho MK, Seong WK, Park KS

  • KMID: 1687903
  • J Korean Soc Microbiol.
  • 1991 Jun;26(3):253-262.
No abstract available.
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