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Neutralizing Antibodies Against Interferon-Beta in Korean Patients with Multiple Sclerosis

Hyun JW, Kim G, Kim Y, Kong B, Joung A, Park NY, Jang H, Shin HJ, Kim SH, Ahn SW, Shin HY, Huh SY, Kim W, Park MS, Kim BJ, Kim BJ, Oh J, Kim HJ

BACKGROUND AND PURPOSE: Patients treated with interferon-beta (IFN-β) can develop neutralizing antibodies (NAbs) against IFN-β that can negatively affect the therapeutic response. This study assessed the prevalence of NAbs and...
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Reduction of Disease Activity in Patient with Relapsing-Remitting Multiple Sclerosis after Switching to Teriflunomide from Interferon Beta

Shin KS, Park JG, Park MS

No abstract available.
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Human Rhinovirus-induced Proinflammatory Cytokine and Interferon-beta Responses in Nasal Epithelial Cells From Chronic Rhinosinusitis Patients

Kim JH, Kim YS, Cho GS, Kim NH, Gong CH, Lee BJ, Jang YJ

PURPOSE: Asthma exacerbation from human rhinovirus (HRV) infection is associated with deficient antiviral interferon (IFN) secretion. Although chronic rhinosinusitis (CRS), an inflammatory upper airway disease, is closely linked to asthma,...
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Combination Therapy for Gliomas Using Temozolomide and Interferon-Beta Secreting Human Bone Marrow Derived Mesenchymal Stem Cells

Park JH, Ryu CH, Kim MJ, Jeun SS

OBJECTIVE: Malignant gliomas are the most common primary tumors of the central nervous system and the prognosis of patients with gliomas is poor. The combination of interferon-bata (IFN-beta) and temozolomide...
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Chronic Inflammatory Demyelinating Polyneuropathy Developed during Interferon-beta Therapy in a Patient with Multiple Sclerosis

Lee CN, Kim BJ, Park KW, Koh SB, Kim HJ, Lee DH

  • KMID: 2065613
  • J Korean Neurol Assoc.
  • 2006 Oct;24(5):486-490.
Preliminary studies have evaluated the effects of interferon beta formulations in the treatment of chronic inflammatory demyelinating polyneuropathy (CIDP) because of pathogenic similarities between CIDP and multiple sclerosis (MS). However,...
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Interferon-beta Induced Skin Necrosis

Bae GY, Chung YI, Park KI, Lee MW, Moon KC, Koh JK

Local cutaneous reactions have been reported at injection sites of interferon therapy, but these are usually erythema or rarely induration. Skin necrosis at the injection site is rare. We describe...
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An Analysis of Combined interferon-beta, BCNU and Radiation in the Treatment of Malignant Glioma

Kye DK, Park YS, Cho KK, Lee KJ, Park SC, Choi CR

  • KMID: 1955058
  • J Korean Neurosurg Soc.
  • 1995 Dec;24(12):1480-1485.
Prognosis for patients with a malignant glioma of the brain is, up to the present time, very poor. Surgery is unlikely to be curative and the primary goals of the...
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