J Korean Neurol Assoc.  2006 Oct;24(5):486-490.

Chronic Inflammatory Demyelinating Polyneuropathy Developed during Interferon-beta Therapy in a Patient with Multiple Sclerosis

Affiliations
  • 1Department of Neurology, Korea University College of Medicine, Seoul, Korea. nukbj@korea.ac.kr

Abstract

Preliminary studies have evaluated the effects of interferon beta formulations in the treatment of chronic inflammatory demyelinating polyneuropathy (CIDP) because of pathogenic similarities between CIDP and multiple sclerosis (MS). However, the efficacy of Interferon, which has been widely used for relapsing-remitting MS, is controversial in CIDP. We report here a 31year old woman with relapsing-remitting type MS treated with IFN beta-1b over 2 years who developed overt CIDP. She responded favorably to steroids. This case suggests that IFN beta-1b treatment may not prevent development of CIDP.

Keyword

Multiple sclerosis; Chronic inflammatory demyelinating polyneuropathy; IFN beta

MeSH Terms

Female
Humans
Interferon-beta*
Interferons
Multiple Sclerosis*
Polyneuropathies*
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
Steroids
Interferon-beta
Interferons
Steroids
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