- Current Antiviral Therapy for Chronic Hepatitis B
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Lim YS, Suh DJ
- KMID: 2157673
- J Korean Med Sci.
- 2004 Aug;19(4):489-494.
- doi: 10.3346/jkms.2004.19.4.489
During the past decade, major breakthroughs have been achieved in treatment of chronic hepatitis B. Currently, three therapeutic agents are approved for chronic hepatitis B: interferon-alpha, lamivudine and adefovir dipivoxil.... -
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- Efficacy of in vitro treatment of chronic myelogenous leukemia cell line, K562 cells, using 4-hydroperoxycyclophosphamide, alpha-interferon and gamma-interferon
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Lee JT, Park S, Lee JH, Kim BK, Kim NK
- KMID: 932127
- J Korean Med Sci.
- 1996 Feb;11(1):26-32.
- doi: 10.3346/jkms.1996.11.1.26
Alpha-interferon (alpha-IFN) and gamma-interferon (gamma-IFN) are highly effective biologic agents in the treatment of chronic myelogenous leukemia (CML). 4-hydroperoxycyclophosphamide (4-HC) is the most commonly used chemotherapeutic drug when purging bone... -
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- Infantile hemangioendothelioma with increased serum alpha-fetoprotein
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Seok JY, Kim YB
- KMID: 1792599
- Korean J Hepatol.
- 2010 Jun;16(2):192-196.
- doi: 10.3350/kjhep.2010.16.2.192
No abstract available. -
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- Renewed 2015 Clinical Practice Guidelines for Management of Hepatitis C by Korean Association for the Study of the Liver; What Has Been Changed? - Treatment of Patients with Decompensated Cirrhosis
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Gwak GY
- KMID: 2373413
- Korean J Gastroenterol.
- 2016 Mar;67(3):137-141.
- doi: 10.4166/kjg.2016.67.3.137
HCV-related decompensated liver cirrhosis is a life-threatening illness with an average 5-year survival rate of 50%. Because these patients have higher risk of morbidity and mortality including development of hepatocellular... -
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- The prediction of interferon-alpha therapeutic effect by sequence variation of the HCV hypervariable region 1
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Yeh BI, Kim HW, Kim HS, Lee JY, Lee KH, Lee KM, Kim JS, Han KH
- KMID: 711674
- Yonsei Med J.
- 1999 Oct;40(5):430-438.
- doi: 10.3349/ymj.1999.40.5.430
Interferon-alpha (IFN-alpha) has been used to treat hepatitis C virus (HCV)-induced hepatitis, but it has been effective in only about half of the treated patients, with recurrence appearing in the... -
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- Combined cis-platinum and alpha interferon therapy of advanced hepatocellular carcinoma
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Ji SK, Park NH, Choi HM, Kim YW, Lee SH, Lee KH, Ahn SY, Lee SU, Han BH, Park BC
- KMID: 1038464
- Korean J Intern Med.
- 1996 Jan;11(1):58-68.
To evaluate the clinical efficacy of alpha-interferon(IFN-alpha) plus cis-platinum in hepatocellular carcinoma(HCC). 56 inoperable patients with HCC were divided into IFN-alpha plus cis-platinum treated group (n = 30) and no... -
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- Renewed 2015 Clinical Practice Guidelines for Management of Hepatitis C by Korean Association for the Study of the Liver; What Has Been Changed? - Treatment of Chronic Hepatitis C Genotype 2 and 3
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Jung YK
- KMID: 2373412
- Korean J Gastroenterol.
- 2016 Mar;67(3):132-136.
- doi: 10.4166/kjg.2016.67.3.132
Ever since direct-acting antiviral agents (DAA) have been approved and released into the world, numerous studies on the efficacy, adverse effects and drug-drug interactions of interferon-free DAA combination therapy have... -
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- Mutations of hepatitis C virus 1b NS5A 2209-2248 amino acid sequence is not a edictive factor for response to interferon-alpha therapy and development of patocellular carcinoma
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Bae SH, Park YM, Yoo DG, Choi JY, Byun BH, Yang JM, Lee CD, Cha SB, Park DH, KiM BS
- KMID: 1731234
- J Korean Med Sci.
- 2000 Feb;15(1):53-58.
- doi: 10.3346/jkms.2000.15.1.53
Genetic changes between codons 2209 and 2248 of NS5A of genotype 1b hepatitis C virus (HCV-1b) have been reported to be associated with the sensitivity to interferon-alpha (IFN-alpha). The present... -
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- Association of IL28B Genotypes and Baseline Serum Interferon-γ-Inducible-Protein-10 Levels with Treatment Response in Hepatitis C Virus Patients in China
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Zhang R, Shao C, Huo N, Li M, Xu X
- KMID: 2411973
- Gut Liver.
- 2016 May;10(3):446-455.
- doi: 10.5009/gnl15162
BACKGROUND/AIMS: Several studies have demonstrated that serum interferon-γ-inducible-protein-10 (IP-10) levels at baseline and single nucleotide polymorphisms (SNPs) near the IL28B gene were associated with viral response and treatment outcomes. Our... -
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- Therapy with Direct-Acting Antiviral Agents for Hepatitis C-Related Liver Cirrhosis
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Toshikuni
- KMID: 2412206
- Gut Liver.
- 2017 May;11(3):335-348.
- doi: 10.5009/gnl15458
Chronic hepatitis C virus (HCV) infection may eventually lead to liver cirrhosis (LC), a condition associated with a high risk of liver failure and hepatocellular carcinoma. Although interferon (IFN)-based therapy... -
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- Renewed 2015 Clinical Practice Guidelines for Management of Hepatitis C by Korean Association for the Study of the Liver; What Has Been Changed? - Treatment of Chronic Hepatitis C Genotype 1
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Park SH
- KMID: 2373411
- Korean J Gastroenterol.
- 2016 Mar;67(3):127-131.
- doi: 10.4166/kjg.2016.67.3.127
The introduction of direct-acting antiviral agents (DAAs) has markedly improved the sustained virological response (SVR) rates in patients with chronic hepatitis C. Currently, four classes of DAAs targeting three HCV... -
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- Renewed 2015 Clinical Practice Guidelines for Management of Hepatitis C by Korean Association for the Study of the Liver; What Has Been Changed? - Indications for Treatment
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Kim KA
- KMID: 2373410
- Korean J Gastroenterol.
- 2016 Mar;67(3):123-126.
- doi: 10.4166/kjg.2016.67.3.123
The landscape of treatment for HCV infection has evolved substantially with the advent of highly effective direct-acting antiviral agents (DAA). The Korean Association for the Study of the Liver updated... -
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- Prevalence, Risk Factors and Clinical Characteristics in Patients with Genotype 6 Chronic Hepatitis C: A Single Institute Experience
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Shin SK, Park SY, Jung YK, Kim EJ, Lee HN, Lee JJ, Kwon OS, Choi DJ, Kim YS, Kim JH
- KMID: 2373191
- Korean J Gastroenterol.
- 2015 Feb;65(2):105-111.
- doi: 10.4166/kjg.2015.65.2.105
BACKGROUND/AIMS: Hepatitis C genotypes 1 and 2 are widely distributed globally. In contrast, genotype 6 is found mainly in Southeast Asia, while genotype 6 is rare in Korea. This study... -
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- The Impact of Inosine Triphosphatase Variants on Hemoglobin Level and Sustained Virologic Response of Chronic Hepatitis C in Korean
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Kim JS, Ahn SM, Jung YK, Kwon OS, Kim YS, Choi DJ, Kim JH
- KMID: 1793028
- J Korean Med Sci.
- 2013 Aug;28(8):1213-1219.
- doi: 10.3346/jkms.2013.28.8.1213
Two variants of the inosine triphosphatase (ITPA: rs1127354, rs7270101) gene cause ITPA deficiency and protect against the hemolytic toxicity of ribavirin. We investigated the clinical significance of ITPA variants in... -
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- Clinical Utility of a New Automated Hepatitis C Virus Core Antigen Assay for Prediction of Treatment Response in Patients with Chronic Hepatitis C
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Kim MN, Kim HS, Kim JK, Kim BK, Kim SU, Park JY, Kim DY, Ahn SH, Han KH
- KMID: 2468276
- J Korean Med Sci.
- 2016 Sep;31(9):1431-1437.
- doi: 10.3346/jkms.2016.31.9.1431
Hepatitis C virus core antigen (HCV Ag) is a recently developed marker of hepatitis C virus (HCV) infection. We investigated the clinical utility of the new HCV Ag assay for... -
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- A Case of Spitzoid Melanoma with Lymph Node Metastasis in a Child
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Kim JY, Choi JE, Ahn HH, Kye YC, Seo SH
- KMID: 2157910
- J Korean Med Sci.
- 2012 Apr;27(4):454-457.
- doi: 10.3346/jkms.2012.27.4.454
The distinction of a spitz nevus from a melanoma can be difficult and in some cases, impossible. A misdiagnosed spitz nevus can metastasize and lead to fatal outcomes, especially in... -
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- Predicting Liver-Related Events Using Transient Elastography in Chronic Hepatitis C Patients with Sustained Virological Response
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Lee HW, Chon YE, Kim SU, Kim BK, Park JY, Kim DY, Ahn SH, Jung KS, Park YN, Han KH
- KMID: 2411971
- Gut Liver.
- 2016 May;10(3):429-436.
- doi: 10.5009/gnl15021
BACKGROUND/AIMS: Few studies have investigated prognostic factors for the development of liver-related events (LREs) in patients with chronic hepatitis C (CHC) who achieve sustained virological response (SVR). METHODS: We analyzed 190... -
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- Advanced fibrosis is not a negative pretreatment predictive factor for genotype 2 or 3 chronic hepatitis C patients
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Lee HS, Kweon YO, Tak WY, Park SY, Kang EJ, Lee YL, Yang HM, Park HW
- KMID: 1776802
- Clin Mol Hepatol.
- 2013 Jun;19(2):148-155.
- doi: 10.3350/cmh.2013.19.2.148
BACKGROUND/AIMS: Chronic hepatitis C patients with advanced fibrosis have unsatisfactory sustained virological response (SVR) rates. Few data demonstrating the efficacy of combination therapy in chronic hepatitis C patients with advanced... -
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- Occult Hepatitis B Virus Infection in Chronic Hepatitis C
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Jang JY, Park EJ
- KMID: 1707197
- Korean J Gastroenterol.
- 2013 Sep;62(3):154-159.
- doi: 10.4166/kjg.2013.62.3.154
Occult HBV infection is defined as the presence of HBV DNA in the liver (with or without detectable or undetectable HBV DNA in the serum) of individuals testing negative for... -
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- No association between the IL28B SNP and response to peginterferon plus ribavirin combination treatment in Korean chronic hepatitis C patients
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Heo NY, Lim YS, Lee W, Oh M, An J, Lee D, Shim JH, Kim KM, Lee HC, Lee YS, Suh DJ
- KMID: 1788567
- Clin Mol Hepatol.
- 2014 Jun;20(2):177-184.
- doi: 10.3350/cmh.2014.20.2.177
BACKGROUND/AIMS: There are few available data regarding the association between the single nucleotide polymorphisms (SNPs) of the gene encoding interleukin 28B (IL28B) and a sustained virologic response (SVR) to peginterferon... -
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