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Role of Reactive Oxygen Species in Allergic Rhinitis

Lee SS

Among many factors explaining recent increase in the prevalence of asthma and allergic rhinitis, role of reactive oxygen species (ROS) during development of these diseases is increasingly considered. Due to...
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Novel inflammatory biomarkers in acute coronary syndrome

Sim DS, Ahn Y

No abstract available.
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Cysteinyl Leukotrienes and Their Receptors; Emerging Concepts

Kanaoka Y, Boyce JA

Cysteinyl leukotrienes (cys-LTs) are potent mediators of inflammation derived from arachidonic acid through the 5-lipoxygenase/leukotriene C4 synthase pathway. The derivation of their chemical structures and identification of their pharmacologic properties...
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The Chloroform Fraction of Carpinus tschonoskii Leaves Inhibits the Production of Inflammatory Mediators in HaCaT Keratinocytes and RAW264.7 Macrophages

Kang GJ, Kang NJ, Han SC, Koo DH, Kang HK, Yoo BS, Yoo ES

  • KMID: 1432309
  • Toxicol Res.
  • 2012 Dec;28(4):255-262.
Inflammation is the immune system's response to infection and injury-related disorders, and is related to pro-inflammatory factors (NO, PGE2, cytokines, etc.) produced by inflammatory cells. Atopic dermatitis (AD) is a...
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Autoimmune Hepatic Failure Following Acute Hepatitis A is Accompanied by Inflammatory Conversion of Regulatory T Cells

Leem G, Kim BK, Shin EC, Park JY

To evaluate the pathophysiology of autoimmune hepatitis (AIH) following acute hepatitis A (AHA) in immunologic aspects, we performed multi-color flow cytometry with peripheral blood mononuclear cells of a patient who...
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Breakthrough in heart failure with preserved ejection fraction: are we there yet?

Lim SL, Lam CS

Heart failure with preserved ejection fraction (HFPEF) is a global health problem of considerable socioeconomic burden. It is projected to worsen with the aging population worldwide. The lack of effective...
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The Study of Morphologic Changes in Reticuloendothelial System of Experimental Rats after Salmonella Typhi Endotoxin Administration

Kim OK

Salmonella typhus endotoxin, a lipopolysaccharide constituent of the cell walls of gram-negative micro-organism, is a major cause of the local inflammation, systemic symptom, and shock. It recently has been reported the...
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The relationship between serum adiponectin and inflammatory cytokines in obese Korean juveniles

Byun SH, Kwon EB, Kim SY

PURPOSE: Obesity is related to systemic inflammatory processes causing cardiovascular complications. Intercellular adhesion molecule-1 (ICAM-1), CD40 ligand (CD40L), P-selectin are newly described mediators of inflammation and have a significant effect...
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Rhupus syndrome

Min JK, Lee KA, Kim HR, Kim HY, Lee SH

No abstract available.
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Effect of Cholesterol Depletion on Interleukin-8 Production in Human Respiratory Epithelial Cells

Kim MJ, Hong JY, Lee KE, Kim KW, Sohn MH, Kim KE

PURPOSE: The lipid entities of cell membranes are components of the immune system and important mediators of inflammation. Despite increasing interest in the function of epithelial cells in inflammation, the...
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Time Course of Inducible NOS Expression of Lung Tissue during Sepsis in a Rat Model

Kim JH, Kim SC, Kwon WY, Suh GJ, Youn YK

  • KMID: 2203509
  • J Korean Soc Traumatol.
  • 2008 Dec;21(2):120-127.
PURPOSE: Many studies on the time course of inducible nitric oxide synthase (iNOS) gene expression have been performed in the LPS (Lipopolysaccharide)-induced endotoxemic model, but there have been few experimental...
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The effects of synovial fluid deficiency on the temporomamdibular joint tissue of rabbits

Park YH, Kim UK, Chung IK

  • KMID: 2190581
  • J Korean Assoc Oral Maxillofac Surg.
  • 1998 Feb;24(1):102-110.
The synovial membrane of the temporomandibular joint lines all the intraarticular structures except the articular cartilage of the articular eminence, fossa, the mandibular condyle and the articular disc. The synovial...
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Inhibitory effect of the aqueous extract of a tetraploid ‘etteum’ variety in Platycodon grandiflorum on degranulation and inflammatory mediator release in RBL-2H3 cells

Jung JI, Kim HS, Ji HK, Lee HS, Lee JY, Kim EJ

PURPOSE: Platycodon grandiflorum (a domestic diploid variety, DV-PG) has been used as a food and component of various traditional oriental medicines. Although DV-PG is known to have an anti-allergic effect,...
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The Expressions of iNOS and COX-2 in the Paraffin-embedded Skin Lesions of the Patients with Leprosy

Kim MH, Choi YW, Choi HY, Myung KB

  • KMID: 2251074
  • Korean J Dermatol.
  • 2001 Feb;39(2):176-182.
BACKGROUND: Nitric oxide(NO) produced by activated macrophages through the action of iNOS is the key molecule in the killing mycobacterium. Prostaglandins produced by the action of COX-2, also, are the...
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Effect of Cyclooxygenase-2 Specific Inhibitor (SC-58635) on the Production of Nitric Oxide and Prostaglandin E2 in Lipopolysaccharide-stimulated Macrophage Cells

Hong SJ, Yang HI, Yoon HJ, Lee MS, Kang HJ, Kim WU, Lee SH, Cho CS, Kim HY

BACKGROUND: Celecoxib, a COX-2 specific inhibitor, has recently been used for the treatment of rheumatoid arthritis. However, the molecular and cellular mechanisms of celecoxib against RA inflammation remain to be...
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Prognostic Inflammation Score in Surgical Patients with Colorectal Cancer

Seong MK

Several inflammatory markers have been investigated as prognostic parameters in a variety of cancer population with mostly favorable results. This study aimed to verify the significance of common inflammatory markers...
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Aralia cordata Extract Activates NF-κB and MAPK Signaling Pathways and Induces Pro-inflammatory Changes in RAW264.7 Macrophages

Seo DW, Cho YI, Yi YJ, Lee SM

Macrophages play essential roles in innate immune responses by producing various immune mediators. Therefore, modulating macrophage function is an attractive strategy to treat immune disorders. Aralia cordata var. continentalis (AC),...
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Microglia, major player in the brain inflammation: their roles in the pathogenesis of Parkinson's disease

Kim YS, Joh TH

  • KMID: 1110117
  • Exp Mol Med.
  • 2006 Aug;38(4):333-347.
Inflammation, a self-defensive reaction against various pathogenic stimuli, may become harmful self-damaging process. Increasing evidence has linked chronic inflammation to a number of neurodegenerative disorders including Alzheimer's disease (AD), Parkinson's...
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Evaluation of the Measurement of Nucleated Red Blood Cells in Neonatal Blood with ADVIA 2120

Park MJ, Song W, Sung TJ, Lee KY

  • KMID: 1466824
  • J Lab Med Qual Assur.
  • 2009 Dec;31(2):233-238.
BACKGROUND: Nucleated red blood cells (NRBCs) are immature erythrocytes. The current line of thought is that increased NRBC production in the immediate neonatal state primarily reflects hypoxic injury and a...
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Metabolic consequences after trauma

Hong YS

  • KMID: 2305519
  • Korean J Leg Med.
  • 1998 Oct;22(2):74-77.
In the multiply traumatized patients, the distinguising feature is the hypermetabolic response to the insult. These response includes an alteration in energy needs and productions, preferential catabolism of body glucose,...
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