- Effects of Combined Upper Limb Robotic Therapy in Patients With Tetraplegic Spinal Cord Injury
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Jung JH, Lee HJ, Cho DY, Lim JE, Lee BS, Kwon SH, Kim HY, Lee SJ
- KMID: 2457753
- Ann Rehabil Med.
- 2019 Aug;43(4):445-457.
- doi: 10.5535/arm.2019.43.4.445
OBJECTIVE: To confirm the effects of combined upper limb robotic therapy (RT) as compared to conventional occupational therapy (OT) in tetraplegic spinal cord injury (SCI) patients and to suggest the... -
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- Influence of Short- and Long-term High-dose Caffeine Administration on Behavior in an Animal Model of Adolescence
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Park JM, Kim Y, Kim H, Kim YJ
- KMID: 2457602
- J Korean Biol Nurs Sci.
- 2019 Aug;21(3):217-223.
- doi: 10.7586/jkbns.2019.21.3.217
PURPOSE: Caffeine is the most widely consumed psychostimulant of the methylxanthine class. Among adolescents, high-dose of caffeine consumption has increased rapidly over the last few decades due to the introduction... -
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- Early-Life Stress in D2 Heterozygous Mice Promotes Autistic-like Behaviors through the Downregulation of the BDNF-TrkB Pathway in the Dorsal Striatum
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Lee Y, Han PL
- KMID: 2451070
- Exp Neurobiol.
- 2019 Jun;28(3):337-351.
- doi: 10.5607/en.2019.28.3.337
A number of specific genetic variants including gene mutations and single nucleotide variations have been identified in genomewide association studies of autism spectrum disorder (ASD). ASD phenotypes in individuals carrying... -
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- Effects of Intraperitoneal N-methyl-D-aspartate (NMDA) Administration on Nociceptive/Repetitive Behaviors in Juvenile Mice
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Kim S, Kim DG, Gonzales E, Mabunga DF, Shin D, Jeon SJ, Shin CY, Ahn T, Kwon KJ
- KMID: 2442008
- Biomol Ther.
- 2019 Feb;27(2):168-177.
- doi: 10.4062/biomolther.2018.230
Dysregulation of excitatory neurotransmission has been implicated in the pathogenesis of neuropsychiatric disorders. Pharmacological inhibition of N-methyl-D-aspartate (NMDA) receptors is widely used to model neurobehavioral pathologies and underlying mechanisms. There... -
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- Long-Term Outcomes of FIM Motor Items Predicted From Acute Stage NIHSS of Patients With Middle Cerebral Artery Infarct
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Saito J, Koyama T, Domen K
- KMID: 2429196
- Ann Rehabil Med.
- 2018 Oct;42(5):670-681.
- doi: 10.5535/arm.2018.42.5.670
OBJECTIVE: To outline the association between the National Institutes of Health Stroke Scale (NIHSS) in the acute stage and the Functional Independence Measure (FIM) of motor items several months later. METHODS:... -
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- Tetramethylpyrazine reverses anxiety-like behaviors in a rat model of post-traumatic stress disorder
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Lee B, Shim I, Lee H, Hahm DH
- KMID: 2419002
- Korean J Physiol Pharmacol.
- 2018 Sep;22(5):525-538.
- doi: 10.4196/kjpp.2018.22.5.525
Post-traumatic stress disorder (PTSD) is a trauma-induced psychiatric disorder characterized by impaired fear extermination, hyperarousal, and anxiety that may involve the release of monoamines in the fear circuit. The reported... -
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- Berberine alleviates symptoms of anxiety by enhancing dopamine expression in rats with post-traumatic stress disorder
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Lee B, Shim I, Lee H, Hahm DH
- KMID: 2410108
- Korean J Physiol Pharmacol.
- 2018 Mar;22(2):183-192.
- doi: 10.4196/kjpp.2018.22.2.183
Post-traumatic stress disorder (PTSD) is a trauma-induced psychiatric disorder characterized by impaired fear extermination, hyperarousal, anxiety, depression, and amnesic symptoms that may involve the release of monoamines in the fear... -
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- Effectiveness of Cognitive Training to Instrumental Activities of Daily Living in Community-Dwelling Elderly
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Lee SM, Lee KH, Lee K, Kwak KP
- KMID: 2358089
- J Korean Geriatr Psychiatry.
- 2016 Oct;20(2):102-107.
- doi: 10.0000/jkgp.2016.20.2.102
OBJECTIVE: This study was aimed to investigate the effectiveness of cognitive training to Instrumental Activities of Daily Living (IADL) in community-dwelling elderly. METHODS: The participant were 786 elders who were aged... -
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- Highly Palatable Food during Adolescence Improves Anxiety-Like Behaviors and Hypothalamic-Pituitary-Adrenal Axis Dysfunction in Rats that Experienced Neonatal Maternal Separation
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Lee JH, Kim JY, Jahng JW
- KMID: 2169424
- Endocrinol Metab.
- 2014 Jun;29(2):169-178.
- doi: 10.3803/EnM.2014.29.2.169
BACKGROUND: This study was conducted to examine the effects of ad libitum consumption of highly palatable food (HPF) during adolescence on the adverse behavioral outcome of neonatal maternal separation. METHODS: Male... -
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- L-Tetrahydropalmatine Ameliorates Development of Anxiety and Depression-Related Symptoms Induced by Single Prolonged Stress in Rats
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Lee B, Sur B, Yeom M, Shim I, Lee H, Hahm DH
- KMID: 2170639
- Biomol Ther.
- 2014 May;22(3):213-222.
Abnormal adaptation of the stress-response system following traumatic stress can lead to alterations in the hypothalamic-pituitary-adrenal (HPA) axis that may contribute to the development of post-traumatic stress disorder (PTSD). The... -
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- Comparison of the Spinal Neuropathic Pain Induced by Intraspinal Injection of N-Methyl-D-Aspartate and Quisquate in Rats
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Choi SS, Hahm KD, Min HG, Leem JG
- KMID: 2190440
- J Korean Neurosurg Soc.
- 2011 Nov;50(5):420-425.
- doi: 10.3340/jkns.2011.50.5.420
OBJECTIVE: Excitatory amino acids play important roles in the development of secondary pathology following spinal cord injury (SCI). This study was designed to evaluate morphological changes in the dorsal horn... -
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- Central Pain from Excitotoxic Spinal Cord Injury Induced by Intraspinal NMDA Injection: A Pilot Study
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Leem YJ, Joh JW, Joeng KW, Suh JH, Shin JW, Leem JG
- KMID: 1770542
- Korean J Pain.
- 2010 Jun;23(2):109-115.
- doi: 10.3344/kjp.2010.23.2.109
BACKGROUND: The pathophysiological and neurochemical changes following spinal injury are not yet elucidated. This study was designed to evaluate the morphological changes of the dorsal horn of the spinal cord... -
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- Recovery State of Hemorrhagic Stroke Patients: Exploratory Comparison of Recovery State between Spontaneous Intracerebral Hemorrhage(s-ICH) and Spontaneous Subarachnoid Hemorrhage(s-SAH)
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Oh HS, Seo WS, Cho HY, Kim MO, Kim MR, Mo J
- KMID: 2290741
- J Korean Acad Adult Nurs.
- 2008 Aug;20(4):600-612.
PURPOSE: This study was conducted to compare the recovery state of 6 month between s-ICH and s-SAH patients. The patients' recovery state was measured with 2 dimensions: functional and cognitive.... -
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- Development of Neuropathic Pain by Thermal Injury using Radiofrequency Thermocoagulation in a Rat Infraorbital Nerve
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Kim SM, Kim CH, Kim HK, Shin SW
- KMID: 1937379
- Korean J Anesthesiol.
- 2007 Nov;53(5):635-640.
- doi: 10.4097/kjae.2007.53.5.635
BACKGROUND: The aim of this study was to investigate the development of neuropathic pain by radiofrequency thermocoagulation on a rat infraorbital nerve (IoN). METHODS: Male Sprague-Dawley rats (n = 35) were... -
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- The Effects of Gabapentin on Facial Formalin Test
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Kim CH, Baik SW, Kim HK, Kwon JY, Kim KH, Choi SH
- KMID: 2237266
- Korean J Anesthesiol.
- 2004 Jan;46(1):91-95.
- doi: 10.4097/kjae.2004.46.1.91
BACKGROUND: Gabapentin is a novel anti-epileptic drug, which is used in clinical practice to treat epilepsy. This drug is also used as an analgesic in pain patients. The antinociceptive effect... -
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- The Effects of Gabapentin on Facial Formalin Test
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Kim CH, Baik SW, Kim HK, Kwon JY, Kim KH, Choi SH
- KMID: 2345172
- J Korean Dent Soc Anesthesiol.
- 2003 Dec;3(2):92-97.
- doi: 10.17245/jkdsa.2003.3.2.92
BACKGROUND: Gabapentin is a novel anti-epileptic drug, which is used in clinical practice to treat epilepsy. This drug is also used as an analgesic in pain patients. The antinociceptive effect... -
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- Age-Related Differences in Rehabilitation Outcome in Cervical Spinal Cord Injury Patients
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Lim JY, Shin HI, Kim GR, Kim DA, Kim JY, Rha IS, Lee ES
- KMID: 1817284
- J Korean Geriatr Soc.
- 2002 Sep;6(3):222-232.
BACKGROUND: The growing number of spinal cord injured individuals facing old age makes the understanding of age related limitations increasingly important. This study was to investigate the age-related differences in... -
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- Behamioral Change and Memory Inpairment Following Transient Forebrain Ischemia in Rats
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Rho CK, Kwon JY, Kim HK, Baik SW, Kim IS, Chung KS
- KMID: 2237088
- Korean J Anesthesiol.
- 1991 Oct;24(5):925-930.
- doi: 10.4097/kjae.1991.24.5.925
This study examined the behavioral change and memory impairment following transient forebrain ischemia in 20 male rats: ten rats were subjected to sham operation. Inchemia was induced by a combination... -
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