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Effect of etoricoxib on experimental oxidative testicular ischemia-reperfusion damage in rats induced with torsion-detorsion

Yapanoglu , Ozkaya F, Yilmaz AH, Mammadov R, Cimen FK, Hirik E, Altuner D

Etoricoxib features antioxidant and anti-inflammatory properties concomitantly, suggesting that it may be beneficial in testicular ischemia reperfusion (I/R) damage. Our aim is to investigate the effects of etoricoxib on testicular...
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Antioxidant mechanism of black garlic extract involving nuclear factor erythroid 2-like factor 2 pathway

Ha AW, Kim WK

BACKGROUN/OBJECTIVES: Although studies have revealed that black garlic is a potent antioxidant, its antioxidant mechanism remains unclear. The objective of this study was to determine black garlic's antioxidant activities and...
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Anti-proliferative Effects of Androctonus amoreuxi Scorpion and Cerastes cerastes Snake Venoms on Human Prostate Cancer Cells

Akef H, Kotb N, Abo-Elmatty D, Salem S

The present study evaluated the effects of Androctonus amoreuxi scorpion venom, Cerastes cerastes snake venom and their mixture on prostate cancer cells (PC3). An MTT assay was used to determine...
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Biochemical Markers of Oxidative Stress in Saudi Women with Recurrent Miscarriage

Ghneim HK, Alshebly M

This study was undertaken to investigate the antioxidant/oxidant status in recurrent miscarriage patients. Antioxidants including glutathione peroxidase (GPx), catalase (CAT), glutathione reductase (GR), reduced glutathione (GSH) and selenium (Se), as...
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Diallyl Disulfide Prevents Cyclophosphamide-Induced Hemorrhagic Cystitis in Rats through the Inhibition of Oxidative Damage, MAPKs, and NF-kappaB Pathways

Kim SH, Lee IC, Ko JW, Moon C, Kim SH, Shin IS, Seo YW, Kim HC, Kim JC

This study investigated the possible effects and molecular mechanisms of diallyl disulfide (DADS) against cyclophosphamide (CP)-induced hemorrhagic cystitis (HC) in rats. Inflammation response was assessed by histopathology and serum cytokines...
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Myeloperoxidase Is Associated with Insulin Resistance and Inflammation in Overweight Subjects with First-Degree Relatives with Type 2 Diabetes Mellitus

Gomez Garcia A, Rodriguez , Gomez Alonso C, Ochoa DY, Alvarez Aguilar C

BACKGROUND: Family history of type 2 diabetes mellitus (T2DM) is one of risk factors for that in future a subject can develop diabetes. Insulin resistance (IR) is important in the...
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Alteration of hepatic anti-oxidant systems by 4-nonylphenol, a metabolite of alkylphenol polyethoxylate detergents, in Far Eastern catfish Silurus asotus

Park KH

OBJECTIVES: This study aimed to estimate the effects of 4-nonylphenol (NP), a ubiquitously present surfactant in aquatic environments, on the anti-oxidant systems of the liver in the Far Eastern catfish...
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Schisandra Chinensis Baillon regulates the gene expression of phase II antioxidant/detoxifying enzymes in hepatic damage induced rats

Jang HI, Do GM, Lee HM, Ok HM, Shin JH, Kwon O

  • KMID: 2313739
  • Nutr Res Pract.
  • 2014 Jun;8(3):272-277.
BACKGROUND/OBJECTIVES: This study investigated the antioxidant activities and hepatoprotective effects of Schisandra chinensis Baillon extract (SCE) against tert-butyl hydroperoxide (t-BHP)-induced oxidative hepatic damage in rats. MATERIALS/METHODS: Sprague-Dawley (SD) rats were pretreated...
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Neuroprotective Effect of Steamed and Fermented Codonopsis lanceolata

Weon JB, Yun BR, Lee J, Eom MR, Ko HJ, Lee HY, Park DS, Chung HC, Chung JY, Ma CJ

  • KMID: 2170643
  • Biomol Ther.
  • 2014 May;22(3):246-253.
Codonopsis lanceolata has been used as an herbal medicine for several lung infl ammatory diseases, such as asthma, tonsillitis, and pharyngitis. Previously, we showed the neuroprotective effect of steamed and...
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Lycopene supplementation suppresses oxidative stress induced by a high fat diet in gerbils

Choi SK, Seo JS

  • KMID: 2313646
  • Nutr Res Pract.
  • 2013 Feb;7(1):26-33.
The effect of lycopene supplementation on the antioxidant system was investigated by analyzing lipid peroxide levels, glutathione contents, and antioxidant enzyme activities in Mongolian gerbils fed a high fat diet....
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Esculetin inhibits N-methyl-D-aspartate neurotoxicity via glutathione preservation in primary cortical cultures

Lee CR, Shin EJ, Kim HC, Choi YS, Shin T, Wie MB

Recently, loss of endogenous glutathione during N-methyl-D-aspartate (NMDA) receptor-mediated excitotoxic injury, and the resultant overproduction of reactive oxygen species (ROS) through an arachidonic acid cascade process in brain, have been...
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Proteomic Evaluation of Cellular Responses of Saccharomyces cerevisiae to Formic Acid Stress

Lee SE, Park BS, Yoon JJ

  • KMID: 2312594
  • Mycobiology.
  • 2010 Dec;38(4):302-309.
Formic acid is a representative carboxylic acid that inhibits bacterial cell growth, and thus it is generally considered to constitute an obstacle to the reuse of renewable biomass. In this...
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Desalinated underground seawater of Jeju Island (Korea) improves lipid metabolism in mice fed diets containing high fat and increases antioxidant potential in t-BHP treated HepG2 cells

Noh JR, Gang GT, Kim YH, Yang KJ, Lee CH, Na OS, Kim GJ, Oh WK, Lee YD

  • KMID: 2421533
  • Nutr Res Pract.
  • 2010 Feb;4(1):3-10.
This study was performed to investigate the effect of desalinated underground seawater (named as 'magma seawater', MSW) of Jeju Island in Korea on lipid metabolism and antioxidant activity. MSW was...
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Glutathione Reductase and Thioredoxin Reductase: Novel Antioxidant Enzymes from Plasmodium berghei

Kapoor G, Banyal HS

Malaria parasites adapt to the oxidative stress during their erythrocytic stages with the help of vital thioredoxin redox system and glutathione redox system. Glutathione reductase and thioredoxin reductase are important...
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Alterations in the blood glucose, serum lipids and renal oxidative stress in diabetic rats by supplementation of onion (Allium cepa. Linn)

Bang MA, Kim HA, Cho YJ

  • KMID: 2313404
  • Nutr Res Pract.
  • 2009 Sep;3(3):242-246.
This study examined the anti-diabetic effect of onion (Allium cepa. Linn) in the streptozotocin (STZ)-induced diabetic rats. Male Sprague-Dawley rats were divided into normal rats fed control diet or supplemented...
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Effects of Salicornia Herbacea L. Supplementation on Antioxidative Enzyme Activities in Streptozotocin-Induced Diabetic Rats

Kim MW

  • KMID: 2263024
  • Korean J Nutr.
  • 2008 Oct;41(7):583-593.
This study was designed to examine the effects of Salicornia herbacea L. (glasswort: GW) on hepatic antioxidative enzyme activities in diabetic rats. Diabetes mellitus was induced in male Sprague-Dawley rats...
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Effects of S-allylcysteine on Oxidative Stress in Streptozotocin-Induced Diabetic Rats

Shin CH, Ihm J

BACKGROUND: An increase in oxidative stress is postulated to contribute to the development of diabetic complications and the use of antioxidant therapy could be protective against these processes. This study...
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Effects of Nicotine, Cotinine and Benzopyrene as Smoke Components on the Expression of Antioxidants in Human Bronchial Epithelial Cells

Kim YS, Lee JH, Kim SH, Kim TH, Sohn JW, Yoon HJ, Park SS, Shin DH

BACKGROUND: Cigarette smoking is an important risk factor for chronic bronchitis and COPD. Airway epithelial cells exposed to cigarette smoke components such as nicotine, cotinine and benzopyrene can generate reactive...
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Effect of Dietary Fat and Genistein on Lipid Metabolism and Antioxidant Activity in Hyperlipidemic Male Rats induced High Fat Diet

Kim MH, Jang SY, Lee YS

  • KMID: 2269934
  • Korean J Nutr.
  • 2006 Mar;39(2):100-108.
This study was conducted to investigate whether dietary factors, normal fat and genistein leads to beneficial improvement of lipid metabolism and oxidative stress in adult hyperlipidemic male rats. Seven wk-old...
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Effects of Vitamin E and Dehydroepiandrosterone on The Formation of Preneoplastic Lesions in Rat Hepatocellular Carcinogenesis

Kim S, Choi H

  • KMID: 2269840
  • Korean J Nutr.
  • 2005 Jun;38(5):364-372.
This study is designed to examine the effects of dietary supplementation with vitamin E and dehydroepiandrosterone (DHEA) on the formation of preneoplastic lesions in diethylnitrosamine (DEN) induced rat hepatocarcinogenesis. All...
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