- Induction of Acute Cyclosporine Nephrotoxicity in Pig
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Kim JY, Lim SW, Ahn KO, Song HK, Ghee JY, Chung BH, Kim YS, Bang BK, Yang CW
- KMID: 2201852
- J Korean Soc Transplant.
- 2007 Jun;21(1):58-62.
PURPOSE: Pigs are promising donor species for xenotransplantation. This study was performed to examine acute cyclosporine (CsA) nephrotoxicity in a pig model. METHODS: Adult pigs were treated daily for 1 week... -
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- Comparison of Early and Late Conversion of Sirolimus in Experimental Model of Chronic Cyclosporine Nephropathy
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Kim JY, Ghee JY, Lim SW, Piao SG, Chung BH, Yoon HE, Hwang HS, Choi BS, Kim J, Yang CW
- KMID: 1120153
- J Korean Med Sci.
- 2012 Feb;27(2):160-169.
- doi: 10.3346/jkms.2012.27.2.160
Sirolimus (SRL) is a promising drug for replacing calcineurin inhibitors. We performed this study to determine the optimal time of conversion from cyclosporine (CsA) to SRL in an experimental model... -
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- Clinical Significance of Monitoring Circulating CD4+CD25+ Regulatory T Cells in Kidney Transplantation during the Early Posttransplant Period
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Kim SH, Oh EJ, Ghee JY, Song HK, Han DH, Yoon HE, Choi BS, Yoon SK, Choi JY, Moon IS, Kim DG, Yang CW
- KMID: 1778153
- J Korean Med Sci.
- 2009 Jan;24(Suppl 1):S135-S142.
- doi: 10.3346/jkms.2009.24.S1.S135
The CD4+CD25+ T regulatory cells (Tregs) play an important role in immune tolerance in experimental transplantation but the clinical significance of circulating Tregs in the peripheral blood is undetermined. In... -
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- Activation of Intrarenal Complement System in Mouse Model for Chronic Cyclosporine Nephrotoxicity
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Kim YO, Lim SW, Li C, Kang HJ, Ahn KO, Yang HJ, Ghee JY, Kim SH, Kim JY, Choi BS, Kim J, Yang CW
- KMID: 724109
- Yonsei Med J.
- 2007 Jun;48(3):517-525.
- doi: 10.3349/ymj.2007.48.3.517
PURPOSE: Local activation of the complement system plays a role in target organ damage. The aim of our study was to investigate the influence of cyclosporine (CsA)- induced renal injury... -
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- Renoprotective Effects of a Highly Selective A3 Adenosine Receptor Antagonist in a Mouse Model of Adriamycin-induced Nephropathy
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Min HS, Cha JJ, Kim K, Kim JE, Ghee JY, Kim H, Lee JE, Han JY, Jeong LS, Cha DR, Kang YS
- KMID: 2468272
- J Korean Med Sci.
- 2016 Sep;31(9):1403-1412.
- doi: 10.3346/jkms.2016.31.9.1403
The concentration of adenosine in the normal kidney increases markedly during renal hypoxia, ischemia, and inflammation. A recent study reported that an A3 adenosine receptor (A3AR) antagonist attenuated the progression... -
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