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Calcium-dependent and -independent mechanisms of P2Y receptor regulated anion secretion in polarized epithelia

Wong HY, Ko WH

No abstract available.
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Receptor-specific Ca2+ signaling in polarized cells

Shin DM, Lee MG, Luo X, Muallem S

No abstract available.
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Epithelial-Mesenchymal Transitions of Bile Duct Epithelial Cells in Primary Hepatolithiasis

Zhao L, Yang R, Cheng L, Wang M, Jiang Y, Wang S

The purpose of this study was to explore the role of epithelial-mesenchymal transition in the pathogenesis of hepatolithiasis. Thirty-one patients with primary hepatolithiasis were enrolled in this study. Expressions of...
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Exposure to Toluene Diisocyanate (TDI) Induces IL-8 Production from Bronchial Epithelial Cells: Effect of Pro-inflammatory Cytokines

Lee YM, Kim HA, Park HS, Lee SK, Nahm DH

This investigation was designed to confirm IL-8 production from human bronchial epithelial cells with toluene diisocyanate (TDI) exposure and to examine the effects of pro-inflammatory cytokine and dexamethasone. We cultured...
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The effective concentration and exposure time of mitomycin-C for the inhibition of lens epithelial cell proliferation in rabbit eyes

You YS, Lim SJ, Chung HS, Lee YG, Kim CY, Hong YJ

The proliferation of residual lens epithelial cells following cataract surgery is assumed to be a major cause of posterior capsular opacification. To assess the efficacy of mitomycin-C in preventing posterior...
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The Expression of E-cadherin in Human and Rat Hepatic Stellate Cells: Evidence of Epithelial-Mesenchymal Transition

Lim YS, Lee HS

  • KMID: 863072
  • Korean J Hepatol.
  • 2002 Mar;8(1):90-99.
BACKGROUND/AIMS: The embryonal origin of hepatic stellate cells (HSCs), the principal cells in hepatic fibrogenesis, is still intriguing. We have previously demonstrated that human HSCs express cytokeratins which suggests...
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The effects of laminin on the characteristics and differentiation of neuronal cells from epidermal growth factor-responsive neuroepithelial cells

Park DS, Park JS, Yeon DS

Many extracellular matrix molecules are expressed in the embryonic nervous system and there is some evidence that they are important regulators of neural development. Of these molecules, laminin appears to...
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The Effect of In Vivo Grown Corneal Epithelium Transplantation on Persistent Epithelial Defects with Limbal Stem Cell Deficiency

Kim JT, Chun YS, Song KY, Kim JC

We report our experience with corneal epithelium, grown in vivo, transplantation in three patients with persistent epithelial defect (PED). The three patients had ocular surface disease unresponsive to standard treatments...
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Degradation of the Transcription Factors NF-kappaB, STAT3, and STAT5 Is Involved in Entamoeba histolytica-Induced Cell Death in Caco-2 Colonic Epithelial Cells

Kim KA, Min A, Lee YA, Shin MH

Entamoeba histolytica is a tissue-invasive protozoan parasite causing dysentery in humans. During infection of colonic tissues, amoebic trophozoites are able to kill host cells via apoptosis or necrosis, both of...
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IGF-1 Counteracts TGF-beta-Mediated Enhancement of Fibronectin for in Vitro Human Lens Epithelial Cells

Chung SH, Jung SA, Cho YJ, Lee JH, Kim EK

PURPOSE: To determine whether insulin-like growth factor (IGF-1) affects transforming growth factor (TGF-beta)- mediated fibronectin accumulation in human lens epithelial cell line (HLE B-3) cells. MATERIALS AND METHODS:...
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Decreased gastric proliferation of foveolar epithelial cells after the eradication of Helicobacter pylori

Jang TJ, Lee JI, Kim JR, Kim DH, Bae SH

Increased epithelial cell proliferation is associated with an increased risk of gastric carcinoma. Helicobacter pylori infection is an established risk factor for gastric cancer and the organism has recently...
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Curcuminoid-phospholipid complex induces apoptosis in mammary epithelial cells by STAT-3 signaling

Cucuzza LS, Motta M, Miretti S, Accornero , Baratta M

Curcumin (from the rhizome of Curcuma longa) is well documented for its medicinal properties in Indian and Chinese systems of medicine where it is widely used for the treatment of...
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Inhibitory effect of receptor for advanced glycation end products (RAGE) on the TGF-beta-induced alveolar epithelial to mesenchymal transition

Song JS, Kang CM, Park CK, Yoon HK, Lee SY, Ahn JH, Moon HS

Idiopathic pulmonary fibrosis (IPF) is a lethal parenchymal lung disease characterized by myofibroblast proliferation. Alveolar epithelial cells (AECs) are thought to produce myofibroblasts through the epithelial to mesenchymal transition (EMT)....
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Cobalt Chloride Attenuates Oxidative Stress and Inflammation through NF-kappaB Inhibition in Human Renal Proximal Tubular Epithelial Cells

Oh SW, Lee YM, Kim S, Chin HJ, Chae DW, Na KY

We evaluated the effect of cobalt chloride (CoCl2) on TNF-alpha and IFN-gamma-induced-inflammation and reactive oxygen species (ROS) in renal tubular epithelial cells (HK-2 cells). We treated HK-2 cells with CoCl2...
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Monocrotaline-induced pulmonary hypertension correlates with upregulation of connective tissue growth factor expression in the lung

Lee YS, Byun J, Kim JA, Lee JS, Kim KL, Suh YL, Kim JM, Jang HS, Lee JY, Shin IS, Suh W, Jeon ES, Kim DK

  • KMID: 1033098
  • Exp Mol Med.
  • 2005 Feb;37(1):27-35.
Pulmonary hypertension (PH) is characterized by structural and functional changes in the lung including proliferation of vascular smooth muscle cells (VSMCs) and excessive collagen synthesis. Although connective tissue growth factor...
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Apoptosis induced in vivo by new type gosling viral enteritis virus

Chen S, Cheng A, Wang M, Zhu D, Jia R, Luo Q, Cui H, Zhou Y, Wang Y, Xu Z, Chen Z, Chen X, Wang X

In this study, apoptosis was induced by new type gosling viral enteritis virus (NGVEV) in experimentally infected goslings is reported in detail for the first time. After 3-day-old goslings were...
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Expression of 4-1BB and 4-1BBL in thymocytes during thymus regeneration

Kim YM, Kim HK, Kim HJ, Lee HW, Ju SA, Choi BK, Kwon BS, Kim BS, Kim JB, Lim YT, Yoon S

4-1BB, a member of the tumor necrosis factor receptor (TNFR) superfamily, is a major costimulatory receptor that is rapidly expressed on the surface of CD4+ and CD8+ T cells after...
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Vesicular transport as a new paradigm in short-term regulation of transepithelial transport

Park CS, Leem CH, Jang YJ, Shim YH

The vectorial transepithelial transport of water and electrolytes in the renal epithelium is achieved by the polarized distribution of various transport proteins in the apical and basolateral membrane. The short-term...
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Bilirubin Activates Transcription of HIF-1alpha in Human Proximal Tubular Cells Cultured in the Physiologic Oxygen Content

Kim SG, Ahn SY, Lee ES, Kim S, Na KY, Chae DW, Chin HJ

The expression of hypoxia-inducible factor (HIF) is influenced by reactive oxygen species (ROS). Effect of bilirubin on HIF-1 expression in proximal tubular cells was investigated under physiological oxygen concentration, which...
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