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A Case of Pyoderma Gangrenosum Treated with Clofazimine

Lee JY, Kang SB, Cho BK, Houh W

  • KMID: 1679778
  • Korean J Dermatol.
  • 1987 Apr;25(2):294-298.
We present herein a case of pyodcrma gangrenosum, who showed good response to clofazimine therapy. The patient, 19-year-old male, had suffered from chronic diarrhea for 10 months before the rapidly...
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A case of Melkersson-Rosenthal syndrome

Bahn JY, Ro YS

  • KMID: 1863727
  • Korean J Dermatol.
  • 2000 Mar;38(3):383-386.
Melkersson-Rosenthal syndrome(MRS) is a rare neuro-muco-cutaneous disease of unknown origin. The classic triad of this clinically defined entity consists of orofacial swelling, facial nerve palsy, and lingua plitica. MRS may occur as...
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The Change of Bacillary Index after Combined Treatment of Dapsone and Clofazimine in Leprosy

Kang SC, Suh MG, Oh SH, Chung SL

  • KMID: 2231660
  • Korean J Dermatol.
  • 1985 Apr;23(2):154-161.
Seventy-seven patients who were treated regularly for more than 5 years in the Taegu Leprosy Mission were investigated with regard to the change of the bacillary index(BI) after treatment of...
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Coloration of the skin on the face due to clofazimine is cleared by Q-switched ND-YAG laser

Jun JH

  • KMID: 1512582
  • Korean Lepr Bull.
  • 2007 Dec;40(2):61-65.
The Clofazimine is a rimino-phenazine dye. The color is a purplish-back. The drug is reported to be weakly bactericidal and also effective in the management of leprosy reactions apparently. The...
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Drugs in leprosy

Park EM

  • KMID: 1512598
  • Korean Lepr Bull.
  • 2006 Jun;39(1):49-58.
Chemotherapy is a main component of treatments for leprosy. The World Health Organization (WHO) recommends multiple-drug therapy (MDT) consisting of dapsone, clofazimine and monthly rifampin as the first-line drugs against...
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A Study of Cutaneous Manifestations by Clofazimine in Leprosy Patients

Kim IJ, Chung SL

  • KMID: 2085541
  • Korean J Dermatol.
  • 1983 Oct;21(5):537-547.
Clofazimine (Lamprene or B668) is a phenazine congener that is used in leprosy, and the patients treated with the drug may develop red discoloration, dark brown pigmentation and ichthyotic skin....
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A Case of Pigmentary Glaucoma Due to Multidrug-Resistant Tuberculosis Treatment

Jung JW, Jo SH, Seo JH, Kim YS

PURPOSE: To report a case of secondary pigmentary glaucoma due to clofazimine treatment for extensive drug-resistant tuberculosis. CASE SUMMARY: A 23-year-old man presented with blurred vision in both eyes. The patient...
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A Case of Sweet's Syndrome which Mimic Panniculitis Treated with High Dose Potassium Iodide

Kim TJ, Yoon SH, Cho MK, Lee SY, Lee JS, Whang KU

  • KMID: 2013664
  • Korean J Dermatol.
  • 2002 May;40(5):571-574.
Sweet's syndrome, first described in 1964 by Sweet, is characterized by fever, neutrophilic leukocytosis, sudden onset of asymmetric, erythematous, often painful skin lesions, and dense dermal infiltrates of mature neutrophils...
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Medical Treatment of Pulmonary Multidrug-Resistant Tuberculosis

Shim TS, Jo KW

Treatment of multidrug-resistant tuberculosis (MDR-TB) is challenging because of the high toxicity of second-line drugs and the longer treatment duration required compared with drug-susceptible TB. The efficacy of treatment for...
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Relapsed Leprosy with Multiple Ulcerative Skin Lesions: A Case Report

Jeong HH, Hong SG, Park JM, Kim JP, Heo EP, Go JW

Leprosy is a chronic infectious and granulomatous disease caused by Mycobacterium leprae. It is treated with a multidrug therapy (MDT), which is consisted of dapsone, rifampicin, and clofazimine. However, there...
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Treatment of Mycobacterium Abscessus Pulmonary Disease

Jhun BW, Koh WJ

Mycobacterium abscessus is the second most important pathogen in pulmonary disease caused by nontuberculous mycobacteria (NTM), following Mycobacterium avium. Mycobacterium abscessus is classified into three subspecies: M. abscessus subsp. abscessus,...
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Diagnosis and Treatment of Multidrug-Resistant Tuberculosis

Shim TS

Despite global efforts to control tuberculosis (TB), multidrug-resistant TB (MDR-TB) is still a serious problem worldwide. The diagnosis of MDR-TB is based on mycobacterial culture followed by drug susceptibility testing,...
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The Bacteriological and Clinical Evaluation of the Effectiveness of Lamprene ( Clofazimine ) on Dapsone ( DDS ) - resisitant Lepromatous Leprosy Patients

Hwang IK, Kim YP

  • KMID: 1920680
  • Korean J Dermatol.
  • 1976 Jun;14(2):131-139.
While for the last thirty years Dapsone (4,4, diaminodiphenyl sulfone; DDS) has been the chemotherapeutic treatment of choice in the management of leprosy, other non-sulfone compounds have been used when...
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Treatment of Mycobacterium avium Complex Pulmonary Disease

Kwon YS, Koh WJ, Daley CL

The pathogen Mycobacterium avium complex (MAC) is the most common cause of nontuberculous mycobacterial pulmonary disease worldwide. The decision to initiate long-term antibiotic treatment is difficult for the physician due...
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