Korean J Dermatol.  1985 Apr;23(2):154-161.

The Change of Bacillary Index after Combined Treatment of Dapsone and Clofazimine in Leprosy

• Kang SC
• Suh MG
• Oh SH
• Chung SL

Abstract

Seventy-seven patients who were treated regularly for more than 5 years in the Taegu Leprosy Mission were investigated with regard to the change of the bacillary index(BI) after treatment of either dapsone(DDS) alone or a combination of DDS and clofazimine. The results were as follows: 1) In the group that took only DDS 400-500 mg per week, the BI conversion to negative took average 51 months. 2) In the group that took only 600-700 mg per week, the BI conversion to negative took average 34 months. 3) In the group that took only DDS 400 mg per week initially and 600-700mg per week secondarily, the BI conversion to negative took average 64 months, the last 33 months of which marked the time period that 600-700 mg were taken per week. 4) In the group that took only DDS 400-500mg per week initially and a combination of DDS gpp 700 mg per week and clofazimine. 3pp-4pp mg per week secondarily, the BI conversion to negative took average 63 months, the last 35 months of which marked the time period for the combined therapy. 5) In the group that took a combination of DDS 600- 700 mg per week and clofazimine 400 mg per week, the BI conversion to negative took average 42 months.

Keyword

Leprosy; Dapsone and clofazimine treatment; BI change

MeSH Terms

Clofazimine*
Daegu
Dapsone*
Humans
Leprosy*
Missions and Missionaries
Clofazimine
Dapsone