Korean J Dermatol.  1987 Apr;25(2):294-298.

A Case of Pyoderma Gangrenosum Treated with Clofazimine

• Lee JY
• Kang SB
• Cho BK
• Houh W

Abstract

We present herein a case of pyodcrma gangrenosum, who showed good response to clofazimine therapy. The patient, 19-year-old male, had suffered from chronic diarrhea for 10 months before the rapidly spreading pustules and ulcers with undermined purple-to-red borders devkloped on his both lower and upper extremitics. Clofazimine was given orally in a dose of 100mg three times daily for 16 days, and tapered to 100 mg two times daily for the next 11 days. Clinical improvement was noted after 7 day's treatment and the almost all of the skin lesiors were replaced by granulation tissue with epithelizatiori or crust formation after 6 days treatment.

Keyword

Pyoderma gangrenosum; Clofazimine

MeSH Terms

Clofazimine*
Diarrhea
Granulation Tissue
Humans
Male
Pyoderma Gangrenosum*
Pyoderma*
Skin
Ulcer
Young Adult
Clofazimine