- Luteolin attenuates migration and invasion of lung cancer cells via suppressing focal adhesion kinase and non-receptor tyrosine kinase signaling pathway
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Masraksa W, Tanasawet , Hutamekalin P, Wongtawatchai T, Sukketsiri W
- KMID: 2471880
- Nutr Res Pract.
- 2020 Apr;14(2):127-133.
- doi: 10.4162/nrp.2020.14.2.127
BACKGROUND/OBJECTIVES: Non-small cell lung cancer is mostly recognized among other types of lung cancer with a poor prognosis by cause of chemotherapeutic resistance and increased metastasis. Luteolin has been found... -
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- Human platelet lysate efficiency, stability, and optimal heparin concentration required in culture of mammalian cells
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Mohamed HE, Asker ME, Kotb NS, El Habab A
- KMID: 2472006
- Blood Res.
- 2020 Mar;55(1):35-43.
- doi: 10.5045/br.2020.55.1.35
BACKGROUND: Fetal bovine serum (FBS) has been used to support the growth and proliferation of mammalian cells for decades. Owing to several risk factors associated with FBS, several trials have... -
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- The optimal model of reperfusion injury in vitro using H9c2 transformed cardiac myoblasts
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Son E, Lee D, Woo CW, Kim YH
- KMID: 2471039
- Korean J Physiol Pharmacol.
- 2020 Mar;24(2):173-183.
- doi: 10.4196/kjpp.2020.24.2.173
An in vitro model for ischemia/reperfusion injury has not been well-established. We hypothesized that this failure may be caused by serum deprivation, the use of glutamine-containing media, and absence of... -
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- The MicroRNA hsa-let-7g Promotes Proliferation and Inhibits Apoptosis in Lung Cancer by Targeting HOXB1
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Cui F, Zhou Q, Xiao K, Ma S
- KMID: 2470917
- Yonsei Med J.
- 2020 Mar;61(3):210-217.
- doi: 10.3349/ymj.2020.61.3.210
PURPOSE: The goal of this study was to explore the effects of hsa-let-7g on cell proliferation and apoptosis, and elucidate its role in lung cancer development. MATERIALS AND METHODS: The expression... -
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- Cytocompatibility and cell proliferation evaluation of calcium phosphate-based root canal sealers
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Mestieri L, Zaccara IM, Pinheiro L, Barletta F, Kopper PM, Grecca FS
- KMID: 2470338
- Restor Dent Endod.
- 2020 Feb;45(1):e2.
- doi: 10.5395/rde.2020.45.e2
OBJECTIVES: This study aimed to evaluate the cell viability and migration of Endosequence Bioceramic Root Canal Sealer (BC Sealer) compared to MTA Fillapex and AH Plus. MATERIALS AND METHODS: BC Sealer,... -
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- Neuroprotective effects of urolithin A on Hâ‚‚Oâ‚‚-induced oxidative stress-mediated apoptosis in SK-N-MC cells
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Kim KB, Lee S, Kim JH
- KMID: 2468507
- Nutr Res Pract.
- 2020 Feb;14(1):3-11.
- doi: 10.4162/nrp.2020.14.1.3
BACKGROUND/OBJECTIVES: Oxidative stress causes cell damage and death, which contribute to the pathogenesis of neurodegenerative diseases. Urolithin A (UA), a gut microbial-derived metabolite of ellagitannins and ellagic acid, has high... -
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- Medium- and long-chain triglyceride propofol reduces the activity of acetyl-coenzyme A carboxylase in hepatic lipid metabolism in HepG2 and Huh7 cells
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Wang LY, Wu J, Gao YF, Lin DM, Ma J
- KMID: 2466566
- Korean J Physiol Pharmacol.
- 2020 Jan;24(1):19-26.
- doi: 10.4196/kjpp.2020.24.1.19
Medium- and long-chain triglyceride (MCT/LCT) propofol is widely used as an intravenous anesthetic, especially in the intensive care unit. The present study aimed to assess whether MCT/LCT propofol is safe... -
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- Effects of dental acid etchants in oral epithelial cells
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Kim DK, Kwak JW, Jo RM, Jung DS, Youn DY, Oh NY, Jang JH
- KMID: 2470508
- Oral Biol Res.
- 2019 Dec;43(4):299-305.
- doi: 10.21851/obr.43.04.201912.299
Phosphoric acid (P.A.; 37%) can induce necrosis on the oral mucosa and cause the ulceration of periodontal tissue. However, most studies reported are clinical case studies, with few basic science... -
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- Capsaicin-Induced Apoptosis in MBT-2 Murine Bladder Tumor Cells and Bladder Wall Penetration Effect of the Nano-Encapsulated Capsaicin in Rabbit
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Cho SJ, Moon HW, Bae WJ, Park YH, Ha US, Hong SH, Kim SW, Lee JY
- KMID: 2470402
- Korean J Urol Oncol.
- 2019 Dec;17(3):168-177.
- doi: 10.22465/kjuo.2019.17.3.168
PURPOSE: In this study, we attempted to characterize capsaicin's effects with regard to the apoptosis of murine bladder cancer cells (MBT-2) as well as the pharmacodynamics of nano-encapsulated capsaicin formulation... -
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- Mechanical properties and biocompatibility of experimental 3D printing denture base resin
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Park DR, Bae JM
- KMID: 2470305
- Korean J Dent Mater.
- 2019 Dec;46(4):253-262.
- doi: 10.14815/kjdm.2019.46.4.253
This study was conducted to compare the flexural properties and biocompatibility of experimental 3D printing resins with commercial 3D-printing resins and conventional denture base resin. Auto polymerized pour-type denture base... -
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- The Protective Effect of Green Tea Extract on Alpha-amanitin Induced Hepatotoxicity
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An SH, Sun KH, Hong R, Lee BR, Park Y
- KMID: 2470188
- J Korean Soc Clin Toxicol.
- 2019 Dec;17(2):58-65.
- doi: 10.22537/jksct.2019.17.2.58
PURPOSE: Alpha-amanitin induces potent oxidative stress and apoptosis, and may play a significant role in the pathogenesis of hepatotoxicity. This study examined the mechanisms of α-amanitin-induced apoptosis in vitro, and... -
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- Inhibition of STAT3 signaling induces apoptosis and suppresses growth of lung cancer: good and bad
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Kang JH, Jang YS, Lee HJ, Lee CY, Shin DY, Oh SH
- KMID: 2470020
- Lab Anim Res.
- 2019 Dec;35(4):221-229.
- doi: 10.1186/s42826-019-0030-0
Signal transducer and activator of transcription 3 (STAT3) modulates a variety of genes involved in the regulation of critical functions, including cell proliferation, differentiation, apoptosis, angiogenesis, metastasis, and immunity. For... -
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- Hypoxia-inducible factor: role in cell survival in superoxide dismutase overexpressing mice after neonatal hypoxia-ischemia
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Jeon GW, Sheldon RA, Ferriero D
- KMID: 2469014
- Korean J Pediatr.
- 2019 Dec;62(12):444-449.
- doi: 10.3345/kjp.2019.00850
BACKGROUND: Sixty percent of infants with severe neonatal hypoxic-ischemic encephalopathy die, while most survivors have permanent disabilities. Treatment for neonatal hypoxic-ischemic encephalopathy is limited to therapeutic hypothermia, but it does... -
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- Genistein Inhibits Proliferation of BRCA1 Mutated Breast Cancer Cells: The GPR30-Akt Axis as a Potential Target
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Kim GY, Suh J, Jang JH, Kim DH, Park OJ, Park SK, Surh YJ
- KMID: 2468809
- J Cancer Prev.
- 2019 Dec;24(4):197-207.
- doi: 10.15430/JCP.2019.24.4.197
BACKGROUND: BRCA1 mutated breast cancer cells exhibit the elevated cell proliferation and the higher metastatic potential. G protein-coupled receptor 30 (GPR30) has been shown to regulate growth of hormonally responsive... -
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- Asiatic Acid Induces Apoptosis and Autophagy and Reduces MiR-17 and MiR-21 Expression in Pancreatic Cancer Cell Lines
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Jo YG, Kim M, Shin H, Lee KY, Lee EJ
- KMID: 2468062
- Nat Prod Sci.
- 2019 Dec;25(4):298-303.
- doi: 10.20307/nps.2019.25.4.298
This study investigated the cytotoxic effects and mechanism of action of asiatic acid in pancreatic cancer cell lines. First, we confirmed the cell viability of MIA PaCa-2 and PANC-1 cells... -
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- Extraneural CGRP Induces Oxidative Stress in Kidney Proximal Tubule Epithelial Cells
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Moon D, Yoon SP, Jang HS, Noh MR, Ha L, Padanilam , Kim J
- KMID: 2467465
- Anat Biol Anthropol.
- 2019 Dec;32(4):121-128.
- doi: 10.11637/aba.2019.32.4.121
Calcitonin gene-related peptide (CGRP) is the most abundant neuropeptide in primary afferent sensory neurons. Exogenous CGRP can induce cell death in kidney tubular cells. The objective of this study was... -
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- Chemical Regeneration of Wound Defects: Relevance to the Canine Palatal Mucosa and Cell Cycle Up-Regulation in Human Gingival Fibroblasts
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Lee K, Ben Amara , Lee SC, Leesungbok R, Chung MA, Koo KT, Lee SW
- KMID: 2467059
- Tissue Eng Regen Med.
- 2019 Dec;16(6):675-684.
- doi: 10.1007/s13770-019-00227-6
BACKGROUND: Trichloroacetic acid (TCA) is an agent widely applied in dermatology for skin regeneration. To test whether TCA can offer an advantage for the regeneration of oral soft tissue defects,... -
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- Evaluation of Polycaprolactone-Associated Human Nasal Chondrocytes as a Therapeutic Agent for Cartilage Repair
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Kim DH, Lim MH, Jeun JH, Park SH, Lee W, Park SH, Kwon MY, Hwang SH, Kim SW
- KMID: 2467053
- Tissue Eng Regen Med.
- 2019 Dec;16(6):605-614.
- doi: 10.1007/s13770-019-00210-1
BACKGROUND: In this study, we manufactured a complex of human nasal septal cartilage (hNC) with polycaprolactone (PCL) for transplantation into cartilaginous skeletal defects and evaluated their characteristics. METHODS: Nasal septum tissue... -
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- Wound Healing Potential of Low Temperature Plasma in Human Primary Epidermal Keratinocytes
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Cui HS, Cho YS, Joo SY, Mun CH, Seo CH, Kim JB
- KMID: 2467051
- Tissue Eng Regen Med.
- 2019 Dec;16(6):585-593.
- doi: 10.1007/s13770-019-00215-w
BACKGROUND: Low temperature plasma (LTP) was recently shown to be potentially useful for biomedical applications such as bleeding cessation, cancer treatment, and wound healing, among others. Keratinocytes are a major... -
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- Effects of remifentanil preconditioning on factors related to uterine contraction in WISH cells
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Kim CH, Lee SH, Kim EJ, Ahn JH, Choi EJ, Yoon JU, Choi IS
- KMID: 2466649
- J Dent Anesth Pain Med.
- 2019 Dec;19(6):343-351.
- doi: 10.17245/jdapm.2019.19.6.343
BACKGROUND: Preterm labor and miscarriage may occur in stressful situations, such as a surgical operation or infection during pregnancy. Pharyngeal and buccal abscess and facial bone fractures are inevitable dental... -
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