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50 results

A Case of Metastatic Low-Grade Endometrial Stromal Sarcoma Treated with Letrozole after Ovarian Ablation by Radiotherapy

Yang KH, Shin JA, Jung JH, Jung HW, Lee HR, Chang S, Park JY, Yi SY

  • Cancer Res Treat.
  • 2015 Oct;47(4):958-962.
  • doi: 10.4143/crt.2014.154
A 50-year-old woman was admitted to our hospital due to multiple lung nodules detected incidentally on a chest X-ray. A video-assisted thoracoscopic lung biopsy revealed low-grade endometrial stromal sarcoma (LG-ESS)....
HPV-Related Retroperitoneal Squamous Cell Carcinoma of Unknown Primary: A Case Report

Oh HJ, Park EH, Lee YB, Hu J, Lee GJ, Chun SH, Lee MY, Lee DW, Kim J, Jin JY

  • Cancer Res Treat.
  • 2015 Oct;47(4):954-957.
  • doi: 10.4143/crt.2014.111
A 56-year-old female was referred to our hospital due to a mass measuring 5 cm in size in the left pelvic cavity, which was found incidentally during a health examination...
Oxaliplatin-Induced Immune-Mediated Thrombocytopenia: A Case Report

Woo HS, Lee KH, Yoon PH, Kim SJ, Park I, Kim YS, Ahn HK, Hong J, Shin DB, Sym SJ

  • Cancer Res Treat.
  • 2015 Oct;47(4):949-953.
  • doi: 10.4143/crt.2014.052
Oxaliplatin is a third-generation platinum derivative used for metastatic or advanced colorectal cancer treatment. Although myelosuppression is the most common cause of oxaliplatin-induced thrombocytopenia, rare cases of oxaliplatin-induced immune-mediated thrombocytopenia...
An Unusual Presentation of Pulmonary Mucosa-Associated Lymphoid Tissue Lymphoma as Diffuse Pulmonary Infiltrates with Spontaneous Regression

Kang HS, Lee HY, Kim SJ, Kim SC, Kim YK, Park GS, Lee KY, Jung JI, Kang JY

  • Cancer Res Treat.
  • 2015 Oct;47(4):943-948.
  • doi: 10.4143/crt.2014.016
A 57-year-old woman presented with cough and dyspnea for 2 months. Computed tomography of the chest showed diffuse ground-glass opacities in both lungs. Histologic examination via thoracoscopic lung biopsy revealed...
Reversible Pulmonary Arterial Hypertension Associated with Dasatinib for Chronic Myeloid Leukemia

Hong JH, Lee SE, Choi SY, Kim SH, Jang EJ, Bang JH, Park JE, Jeon HR, Oh YJ, Yi JE, Jung HO, Youn HJ, Kim DW

  • Cancer Res Treat.
  • 2015 Oct;47(4):937-942.
  • doi: 10.4143/crt.2013.155
We describe two cases of pulmonary arterial hypertension (PAH) that occurred under dasatinib treatment and were resolved after dasatinib discontinuation. Two patients with chronic phase chronic myeloid leukemia (CML) were...
Conventional Cisplatin-Based Combination Chemotherapy Is Effective in the Treatment of Metastatic Spermatocytic Seminoma with Extensive Rhabdomyosarcomatous Transformation

Jeong Y, Cheon J, Kim TO, Lim DH, Lee S, Cho YM, Hong JH, Lee JL

  • Cancer Res Treat.
  • 2015 Oct;47(4):931-936.
  • doi: 10.4143/crt.2014.049
A 52-year-old man was presented with a huge left testicular mass and palpable cervical lymphadenopathy with retroperitoneal lymph node enlargement on an abdominal computed tomography. A left radical orchiectomy and...
Tumor Growth Suppression and Enhanced Radioresponse by an Exogenous Epidermal Growth Factor in Mouse Xenograft Models with A431 Cells

Lim YJ, Jeon SR, Koh JM, Wu HG

  • Cancer Res Treat.
  • 2015 Oct;47(4):921-930.
  • doi: 10.4143/crt.2014.153
PURPOSE: The purpose of this study was to evaluate whether an exogenous epidermal growth factor (EGF) could induce anti-tumor and radiosensitizing effects in vivo. MATERIALS AND METHODS: BALB/c-nu mice that were...
A Novel, Potent, Small Molecule AKT Inhibitor Exhibits Efficacy against Lung Cancer Cells In Vitro

Dinavahi S, Prasanna R, Dharmarajan S, Perumal Y, Viswanadha S

  • Cancer Res Treat.
  • 2015 Oct;47(4):913-920.
  • doi: 10.4143/crt.2014.057
PURPOSE: Anomalies of Akt regulation, including overexpression in lung cancer, impart resistance to conventional chemotherapy and radiation, thereby implicating this kinase as a therapeutic intervention point. A novel scaffold of...
Role of Radiotherapy in the Multimodal Treatment of Ewing Sarcoma Family Tumors

Choi Y, Lim DH, Lee SH, Lyu CJ, Im JH, Lee YH, Suh CO

  • Cancer Res Treat.
  • 2015 Oct;47(4):904-912.
  • doi: 10.4143/crt.2014.158
PURPOSE: The aim of this study was to evaluate the role of radiotherapy (RT) in the management of Ewing sarcoma family tumors (ESFT). MATERIALS AND METHODS: Retrospective analysiswas performed on 91...
Long-term Outcome of Chondrosarcoma: A Single Institutional Experience

Bindiganavile S, Han I, Yun JY, Kim HS

  • Cancer Res Treat.
  • 2015 Oct;47(4):897-903.
  • doi: 10.4143/crt.2014.135
PURPOSE: The prognostic factors of chondrosarcoma remain uncertain as only a few large studies with long-term follow-up have been reported. The aim of this study was to analyze oncological outcomes...
Extra-cranial Malignant Rhabdoid Tumor in Children: A Single Institute Experience

Hong CR, Kang HJ, Ju HY, Lee JW, Kim H, Park SH, Kim IH, Park KD, Shin HY

  • Cancer Res Treat.
  • 2015 Oct;47(4):889-896.
  • doi: 10.4143/crt.2013.176
PURPOSE: Malignant rhabdoid tumor (MRT) is a rare and highly aggressive tumor that affects young children. Due to its extreme rarity, most of the available data are based on retrospective...
Patterns of Failure Following Multimodal Treatment for Medulloblastoma: Long-Term Follow-up Results at a Single Institution

Lee DS, Cho J, Kim SH, Kim DS, Shim KW, Lyu CJ, Han JW, Suh CO

  • Cancer Res Treat.
  • 2015 Oct;47(4):879-888.
  • doi: 10.4143/crt.2014.067
PURPOSE: The purpose of this study is to investigate the long-term results and appropriateness of radiation therapy (RT) for medulloblastoma (MB) at a single institution. MATERIALS AND METHODS: We analyzed the...
Role of Chemotherapy in Stage II Nasopharyngeal Carcinoma Treated with Curative Radiotherapy

Kang MK, Oh D, Cho KH, Moon SH, Wu HG, Heo DS, Ahn YC, Park K, Park HJ, Park JS, Keum KC, Cha J, Kim JW, Kim YS, Kang JH, Oh YT, Kim JY, Kim SH, Kim JH, Lee CG

  • Cancer Res Treat.
  • 2015 Oct;47(4):871-878.
  • doi: 10.4143/crt.2014.141
PURPOSE: To define the role of neoadjuvant and concurrent chemotherapy in stage II nasopharyngeal carcinoma, we compared the treatment outcomes of patients treated with curative radiotherapy with or without chemotherapy. MATERIALS...
Long-Term Outcome of Definitive Radiotherapy for Early Glottic Cancer: Prognostic Factors and Patterns of Local Failure

Lim YJ, Wu HG, Kwon TK, Hah JH, Sung MW, Kim KH, Park CI

  • Cancer Res Treat.
  • 2015 Oct;47(4):862-870.
  • doi: 10.4143/crt.2014.203
PURPOSE: This study evaluates the long-term results of definitive radiotherapy (RT) for early glottic cancer. Clinical and treatment factors related to local control and patterns of failure are analyzed. MATERIALS AND...
ATAD2 as a Poor Prognostic Marker for Hepatocellular Carcinoma after Curative Resection

Hwang HW, Ha SY, Bang H, Park CK

  • Cancer Res Treat.
  • 2015 Oct;47(4):853-861.
  • doi: 10.4143/crt.2014.177
PURPOSE: Cancer cells frequently express genes that are specifically or preferentially expressed in male germ cells under normal conditions. The ATPase family AAA domain-containing 2 (ATAD2) is one such and...
Expression of PEG10 Is Associated with Poor Survival and Tumor Recurrence in Hepatocellular Carcinoma

Bang H, Ha SY, Hwang SH, Park CK

  • Cancer Res Treat.
  • 2015 Oct;47(4):844-852.
  • doi: 10.4143/crt.2014.124
PURPOSE: Paternally expressed gene 10 (PEG10), first identified as an imprinted gene, is paternally expressed and maternally silenced. In hepatocellular carcinoma (HCC), PEG10 has been identified as a potential target...
Detecting Metastatic Bladder Cancer Using 18F-Fluorodeoxyglucose Positron-Emission Tomography/Computed Tomography

Ozturk H

  • Cancer Res Treat.
  • 2015 Oct;47(4):834-843.
  • doi: 10.4143/crt.2014.157
PURPOSE: The purpose of this study was to retrospectively investigate the contribution of 18F-fluorodeoxyglucose-positron emission tomography/computed tomography (18F-FDG-PET/CT) to detection of metastatic bladder cancer. MATERIALS AND METHODS: The present study included...
APE1/Ref-1 as a Serological Biomarker for the Detection of Bladder Cancer

Shin JH, Choi S, Lee YR, Park MS, Na YG, Irani K, Lee SD, Park JB, Kim JM, Lim JS, Jeon BH

  • Cancer Res Treat.
  • 2015 Oct;47(4):823-833.
  • doi: 10.4143/crt.2014.074
PURPOSE: Apurinic/apyrimidinic endonuclease 1/redox factor-1 (APE1/Ref-1) is a multifunctional protein that shows elevated expression in a number of cancers. We attempted to determine whether serum APE1/Ref-1 is elevated in patients...
Prognostic Significance of Defining L-Cell Type on the Biologic Behavior of Rectal Neuroendocrine Tumors in Relation with Pathological Parameters

The Gastrointestinal Pathology Study Group of Korean Society of Pathologists, Sohn JH, Cho MY, Park Y, Kim H, Kim WH, Kim JM, Jung ES, Kim KM, Lee JH, Chan HK, Park DY, Joo M, Kim S, Moon WS, Kang MS, Jin SY, Kang YK, Yoon SO, Han H, Choi E

  • Cancer Res Treat.
  • 2015 Oct;47(4):813-822.
  • doi: 10.4143/crt.2014.238
PURPOSE: In 2010, the World Health Organization categorized L-cell type neuroendocrine tumors (NETs) as tumors of uncertain malignancy, while all others were classified as malignant. However, the diagnostic necessity of...
GRP78 Protein Expression as Prognostic Values in Neoadjuvant Chemoradiotherapy and Laparoscopic Surgery for Locally Advanced Rectal Cancer

Lee HY, Jung JH, Cho HM, Kim SH, Lee KM, Kim HJ, Lee JH, Shim BY

  • Cancer Res Treat.
  • 2015 Oct;47(4):804-812.
  • doi: 10.4143/crt.2014.121
PURPOSE: We investigated the relationships between biomarkers related to endoplasmic reticulum stress proteins (glucose-regulated protein of molecular mass 78 [GRP78] and Cripto-1 [teratocarcinoma-derived growth factor 1 protein]), pathologic response, and...

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