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Sarcoidosis Mimicking Cancer Metastasis Following Chemotherapy for Ovarian Cancer

Kim MH, Lee K, Kim KU, Park HK, Lee MK, Suh DS

  • Cancer Res Treat.
  • 2013 Dec;45(4):354-358.
We report on a rare case of sarcoidosis that developed after chemotherapy for ovarian cancer, and mimicked a cancer metastasis. A 52-year-old female diagnosed with stage III ovarian cancer underwent...
Sunitinib Treatment for Metastatic Renal Cell Carcinoma in Patients with Von Hippel-Lindau Disease

Kim HC, Lee JS, Kim SH, So HS, Woo CY, Lee JL

  • Cancer Res Treat.
  • 2013 Dec;45(4):349-353.
Von Hippel-Lindau (VHL) disease is an autosomal dominant disease that produces a variety of tumors and cysts in the central nervous system and visceral organs, including renal cell carcinoma (RCC)....
Tumor Lysis Syndrome in a Solid Tumor: A Case Report of a Patient with Invasive Thymoma

Lee JY, Lim SH, Lee JY, Kim JH, Choi KH, Park K, Sun JM, Ahn JS, Ahn MJ

  • Cancer Res Treat.
  • 2013 Dec;45(4):343-348.
Tumor lysis syndrome (TLS) has rarely been observed in solid tumors. We report on a case of a patient with advanced invasive thymoma who developed tumor lysis syndrome after chemotherapy....
Sequence-Dependent Radiosensitization of Histone Deacetylase Inhibitors Trichostatin A and SK-7041

Kim JH, Kim IH, Shin JH, Kim HJ, Kim IA

  • Cancer Res Treat.
  • 2013 Dec;45(4):334-342.
PURPOSE: This preclinical study is to determine whether the capacity of histone deacetylase (HDAC) inhibitors to enhance radiation response depends on temporal sequences of HDAC inhibition and irradiation. MATERIALS AND METHODS:...
Clinical Implications of VEGF, TGF-beta1, and IL-1beta in Patients with Advanced Non-small Cell Lung Cancer

Kim JW, Koh Y, Kim DW, Ahn YO, Kim TM, Han SW, Oh DY, Lee SH, Im SA, Kim TY, Heo DS, Bang YJ

  • Cancer Res Treat.
  • 2013 Dec;45(4):325-333.
PURPOSE: Vascular endothelial growth factor (VEGF)-A, VEGF165b, interleukin (IL)-1beta, and transforming growth factor (TGF)-beta1 are known to influence tumor angiogenesis. Clinical implications of these cytokines need to be elucidated. MATERIALS AND...
Effects of Polymorphisms of Innate Immunity Genes and Environmental Factors on the Risk of Noncardia Gastric Cancer

Kim J, Cho YA, Choi IJ, Lee YS, Kim SY, Hwang JA, Cho SJ, Kook MC, Kim CG, Kim YW

  • Cancer Res Treat.
  • 2013 Dec;45(4):313-324.
PURPOSE: Increasing evidence suggests that polymorphisms in innate immunity genes are associated with Helicobacter pylori-induced inflammation and may influence susceptibility in developing noncardia gastric cancer. Therefore, we investigate the effect...
Immunogenicity of Influenza Vaccine in Colorectal Cancer Patients

Kim DH, Lee YY, Shin US, Moon SM

  • Cancer Res Treat.
  • 2013 Dec;45(4):303-312.
PURPOSE: Although influenza is regarded as a major cause of morbidity and mortality in immunocompromised patients, vaccine coverage remains poor. We evaluated the immunogenicity of influenza vaccines in colorectal cancer...
Predictive Factors for Radiation Pneumonitis in Lung Cancer Treated with Helical Tomotherapy

Kim Y, Hong SE, Kong M, Choi J

  • Cancer Res Treat.
  • 2013 Dec;45(4):295-302.
PURPOSE: Predictive factors for radiation pneumonitis (RP) after helical tomotherapy (HT) may differ from those after linac-based radiotherapy. In this study, we identified predictive factors for RP in patients with...
Nomogram to Predict Treatment Outcome of Fluoropyrimidine/Platinum-Based Chemotherapy in Metastatic Esophageal Squamous Cell Carcinoma

Jung HA, Adenis A, Lee J, Park SH, Maeng CH, Park S, Ahn HK, Shim YM, Penel N, Im YH

  • Cancer Res Treat.
  • 2013 Dec;45(4):285-294.
PURPOSE: The degree of benefit from palliative chemotherapy differs widely among patients with metastatic esophageal squamous cell carcinoma (MESCC). The purpose of this study was to develop and validate a...
Clinical Prognostic Factors for Locally Advanced Esophageal Squamous Carcinoma Treated after Definitive Chemoradiotherapy

Kim DE, Kim UJ, Choi WY, Kim MY, Kim SH, Kim MJ, Shim HJ, Hwang JE, Bae WK, Chung IJ, Nam TK, Na KJ, Cho SH

  • Cancer Res Treat.
  • 2013 Dec;45(4):276-284.
PURPOSE: Locally advanced esophageal cancers are generally treated with neoadjuvant chemoradiotherapy, followed by surgery in operable candidates. However, even if the patients were diagnosed as operable disease, surgery could not...
Trends in the Aggressiveness of End-of-Life Care for Advanced Stomach Cancer Patients

Hong JH, Rho SY, Hong YS

  • Cancer Res Treat.
  • 2013 Dec;45(4):270-275.
PURPOSE: It is important to balance the appropriateness of active cancer treatments and end-of-life care to improve the quality of life for terminally ill cancer patients. This study describes the...
Effect of Dose Escalation with Single Opioid, Fentanyl Matrix in Patients Not Controlling Cancer Pain: A Multicenter, Prospective, Observational Study in Korea

Koh SA, Lee KH, Kim MJ, Lee KT, Park SW, Nam SH, Ryoo HM

  • Cancer Res Treat.
  • 2013 Dec;45(4):263-269.
PURPOSE: End-of-dose failure (EOD) is a clinically common observation and many cancer patients increase the frequency of opioid administration. Fentanyl matrix use is known to be effective in patients with...
Targeting Arginine-Dependent Cancers with Arginine-Degrading Enzymes: Opportunities and Challenges

Phillips M, Sheaff MT, Szlosarek

  • Cancer Res Treat.
  • 2013 Dec;45(4):251-262.
Arginine deprivation is a novel antimetabolite strategy for the treatment of arginine-dependent cancers that exploits differential expression and regulation of key urea cycle enzymes. Several studies have focused on inactivation...

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