- Differential Cell Analysis and Lymphocyte Subset Analysis in Bronchoalveolar Lavage Fluid from Patients with Miliary Tuberculosis
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Kim JE, Seol HY, Cho WH, Kim KU, Jeon DS, Park HK, Kim YS, Lee MK, Park SK
- KMID: 2319310
- Tuberc Respir Dis.
- 2010 Apr;68(4):218-225.
BACKGROUND: Bronchoalveolar lavage (BAL) is a useful technique to recover lower airway fluid and cells involved in many respiratory diseases. Miliary tuberculosis is potentially lethal, but the clinical manifestations are... -
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- Maintenance of CD8+T-cell anergy by CD4+CD25+ regulatory T cells in chronic graft-versus-host disease
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Kim J, Kim HJ, Choi WS, Nam SH, Cho HR, Kwon B
- KMID: 1098083
- Exp Mol Med.
- 2006 Oct;38(5):494-501.
In a murine model of systemic lupus erythematosus (SLE)-like chronic graft-versus-host disease (cGVHD), donor CD8+T cells rapidly fall into anergy to host cells, while donor CD4+T cells hyperactivate B cells... -
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- Regional differences in the density of Langerhans cells, CD8-positive T lymphocytes and CD68-positive macrophages: a preliminary study using elderly donated cadavers
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Omine Y, Hinata N, Yamamoto M, Kasahara M, Matsunaga , Murakami G, Abe SI
- KMID: 2424820
- Anat Cell Biol.
- 2015 Sep;48(3):177-187.
- doi: 10.5115/acb.2015.48.3.177
To provide a better understanding of the local immune system in the face and external genitalia, i.e., the oral floor, lower lip, palpebral conjunctiva, anus and penis, we examined the... -
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- Peripheral blood lymphocyte subsets in patients with stomach cancer
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Hong WS, Min YI, Son YS, Hong SI
- KMID: 1054339
- J Korean Med Sci.
- 1995 Jun;10(3):164-168.
- doi: 10.3346/jkms.1995.10.3.164
The present study was conducted in order to investigate the immunologic alterations alongside the numerical changes in peripheral blood lymphocytes(PBL) and their subsets in stomach cancer patients. Lymphocyte surface markers... -
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- The presence of CD8+ invariant NKT cells in mice
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Lee H, Hong C, Shin J, Oh S, Jung S, Park YK, Hong S, Lee GR, Park SH
- KMID: 1099863
- Exp Mol Med.
- 2009 Dec;41(12):866-872.
- doi: 10.3858/emm.2009.41.12.092
Invariant natural killer T (iNKT) cells develop in the thymus upon recognition of CD1d expressed on developing thymocytes. Although CD4 and CD8 coreceptors are not directly involved in the interaction... -
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- Quantitation of T-lymphocyte Subsets Using the CELL-DYN Sapphire Automated Haematology Analyser
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Kim J, Ryu S, Lim J, Kwon G, Koo S
- KMID: 2200452
- J Lab Med Qual Assur.
- 2014 Mar;36(1):39-47.
BACKGROUND: Quantitative analysis of T-lymphocyte subsets is used to assess immune competency. Traditionally, T-lymphocyte subset analysis has been performed using flow cytometry, which requires complex instrumentation and relatively skilled manual... -
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- Expression of Hepatitis C Virus Core Protein in Hepatocytes Does Not Modulate Proliferation or Apoptosis of CD8+ T Cells
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Jin YH, Crispe IN, Park S
- KMID: 2428300
- Yonsei Med J.
- 2005 Dec;46(6):827-834.
Hepatocytes are the primary targets of the hepatitis C virus (HCV). While immunosuppressive roles of HCV core protein have been found in several studies, it remains uncertain whether core protein... -
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- Kaposi's Sarcoma Associated with Gastric Involvement
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Lee BG, Lee MH, Kim NI, Haw CR
- KMID: 2362131
- Ann Dermatol.
- 1989 Jul;1(2):114-118.
- doi: 10.5021/ad.1989.1.2.114
We report a case of classic Kaposi's sarcoma (KS) in a 67-year-old man, who had multiple cutaneous lesions of the feet and left hand as well as an internal involvement... -
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- In vivo ligation of glucocorticoid-induced TNF receptor enhances the T-cell immunity to herpes simplex virus type 1
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La S, Kim E, Kwon B
- KMID: 1056231
- Exp Mol Med.
- 2005 Jun;37(3):193-198.
GITR (glucocorticoid-induced TNF receptor) is a recently identified member of the TNF receptor superfamily. The receptor is preferentially expressed on CD4+CD25+ regulatory T cells and GITR signals break the suppressive... -
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- Carcinoma with Predominant Lymphoid Stroma in Hepatobiliary System: Report of 2 Cases
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Min HS, Shin E, Jang JJ
- KMID: 760725
- Korean J Hepatol.
- 2007 Jun;13(2):222-227.
Lymphoepithelioma-like carcinoma (LELC) is an undifferentiated carcinoma with predominant lymphocytic infiltration, which is associated with Epstein-Barr virus (EBV) in variable proportions. We report two cases of carcinoma with predominant lymphoid... -
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- Antitumor immunity induced by tumor cells engineered to express a membrane-bound form of IL-2
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Chang MR, Lee WH, Choi JW, Park SO, Paik SG, Kim YS
- KMID: 1056237
- Exp Mol Med.
- 2005 Jun;37(3):240-249.
Transduction of cytokine gene into tumor cells is a promising method of tumor therapy, but the value is limited by accompanying side effects. To focus antitumor immune response to tumor... -
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- The Expression of Programmed Death-1 in Circulating CD4+ and CD8+ T Cells during Hepatitis B Virus Infection Progression and Its Correlation with Clinical Baseline Characteristics
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Xu P, Chen YJ, Chen H, Zhu XY, Song HF, Cao LJ, Wang XF
- KMID: 1774547
- Gut Liver.
- 2014 Mar;8(2):186-195.
BACKGROUND/AIMS: Programmed death-1 (PD-1) expression was investigated in CD4+ and CD8+ T cells from hepatitis B virus (HBV)-infected patients at the chronic hepatitis B (CHB) infection, liver cirrhosis (LC), and... -
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- Attenuation of Peripheral Regulatory T-Cell Suppression of Skin-Homing CD8+T Cells in Atopic Dermatitis
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Zhang BX, Lyu JC, Liu HB, Feng DQ, Zhang DC, Bi XJ, Duan ZW, Ding G
- KMID: 2352807
- Yonsei Med J.
- 2015 Jan;56(1):196-203.
- doi: 10.3349/ymj.2015.56.1.196
PURPOSE: Cutaneous lymphocyte-associated antigen (CLA)-expressing CD8+T cells have been known to play an important role in the pathogenesis of atopic dermatitis (AD). However, the mechanisms underlying the loss of self-tolerance... -
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- Relation between lymphocyte subpopulations of peripheral blood and immune responses of modified live hog cholera virus vaccine in pigs treated with an ionized alkali mineral complex
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Park BK, Park YH, Seo KS
- KMID: 1103474
- J Vet Sci.
- 2000 Jun;1(1):49-52.
Thirty-nine healthy pigs (28-32 days old) were purchased from a commercial swine farm and housed at swine pens of the College. The animals were vaccinated intramuscularly (1 ml) with an... -
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- Two-signal blockade with anti-CD45RB and anti-CD154 monoclonal antibodies inhibits graft rejection via CD4-dependent mechanisms in allogeneic skin transplantation
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Kim EY, Lee EN, Lee J, Park HJ, Chang CY, Jung DY, Choi SY, Lee SK, Joh JW, Kim SJ
- KMID: 1094154
- Exp Mol Med.
- 2006 Jun;38(3):284-294.
Blockade of signal 1 or 2 for T-cell activation by the use of anti-CD45RB and anti-CD154 monoclonal antibodies (mAb) (two-signal blockade) has been proven effective in preventing or delaying graft... -
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- Identificaiton of Novel Immunogenic Human Papillomavirus Type 16 E7-Specific Epitopes Restricted to HLA-A*33;03 for Cervical Cancer Immunotherapy
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Kim S, Chung HW, Kong HY, Lim JB
- KMID: 2374187
- Yonsei Med J.
- 2017 Jan;58(1):43-50.
- doi: 10.3349/ymj.2017.58.1.43
PURPOSE: To identify new immunogenic HLA-A*33;03-restricted epitopes from the human papillomavirus (HPV) 16 E7 protein for immunotherapy against cervical cancer. MATERIALS AND METHODS: We synthesized fourteen overlapping 15-amino acid peptides and... -
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- Efficient amplification of melanoma-specific CD8+ T cells using artificial antigen presenting complex
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Chang J
- KMID: 1115936
- Exp Mol Med.
- 2006 Dec;38(6):591-598.
In vitro large amplification of tumor-specific cytotoxic T lymphocytes (CTLs) and adoptive transfer of these cells is one of the most promising approaches to treat malignant diseases in which an... -
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- Unique features of bovine lymphocytes exposed to a staphylococcal enterotoxin
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Park YH, Lee SU, Ferens WA, Samuels S, Davis WC, Fox LK, Ahn JS, Seo KS, Chang BS, Hwang SY, Bohach GA
- KMID: 1089907
- J Vet Sci.
- 2006 Sep;7(3):233-239.
- doi: 10.4142/jvs.2006.7.3.233
We previously demonstrated that stimulation of bovine peripheral blood mononuclear cells (PBMCs) with staphylococcal enterotoxin C (SEC), led to an inversion of the CD4(+):CD8(+) T cell ratio and generation of... -
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- Apoptosis of T Lymphocytes Isolated from Peripheral Blood of Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
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Lim SC, Ju JY, Chi SY, Ban HJ, Kwon YS, Oh IJ, Kim KS, Kim YI, Kim YC
- KMID: 1727989
- Yonsei Med J.
- 2011 Jul;52(4):581-587.
- doi: 10.3349/ymj.2011.52.4.581
PURPOSE: Chronic obstructive pulmonary disease (COPD) is characterized by chronic inflammation of the airways and progressive destruction of lung parenchyma. Apoptosis is critical for the maintenance of normal tissue homeostasis... -
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- Chemokine Receptor Expression of Hepatitis B Virus-Specific CD8+ Lymphocyte in Chronic B Viral Infection
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Lee CK, Suh JH, Cho YS, Han KH, Chung JB, Chon CY, Moon YM
- KMID: 863111
- Korean J Hepatol.
- 2002 Dec;8(4):363-370.
BACKGROUND/AIMS: The protective role of HBV-specific CD8+ cells is dependent on their ability to efficiently migrate to the infected liver, where they may exert an effector function. The migratory... -
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