- Recent Advances of Vaccine Adjuvants for Infectious Diseases
-
Lee S, Nguyen MT
- KMID: 2168029
- Immune Netw.
- 2015 Apr;15(2):51-57.
- doi: 10.4110/in.2015.15.2.51
Vaccines are the most effective and cost-efficient method for preventing diseases caused by infectious pathogens. Despite the great success of vaccines, development of safe and strong vaccines is still required... -
- CITED
-
- Close
- SHARE
-
- Close
- Vaccine adjuvant materials for cancer immunotherapy and control of infectious disease
-
Lim YT
- KMID: 2049107
- Clin Exp Vaccine Res.
- 2015 Jan;4(1):54-58.
- doi: 10.7774/cevr.2015.4.1.54
Adjuvants can be defined as pharmacological and immunological components that are able to modify and/or enhance antigen-specific immune responses. Based on the interdisciplinary research between immunology and material science/engineering, various... -
- CITED
-
- Close
- SHARE
-
- Close
- Improvement of DNA vaccination by adjuvants and sophisticated delivery devices: vaccine-platforms for the battle against infectious diseases
-
Grunwald T, Ulbert S
- KMID: 2049102
- Clin Exp Vaccine Res.
- 2015 Jan;4(1):1-10.
- doi: 10.7774/cevr.2015.4.1.1
Advantages of DNA vaccination against infectious diseases over more classical immunization methods include the possibilities for rapid manufacture, fast adaptation to newly emerging pathogens and high stability at ambient temperatures.... -
- CITED
-
- Close
- SHARE
-
- Close
- A Current Research Insight into Function and Development of Adjuvants
-
Sohn ES, Son E, Pyo S
- KMID: 2167974
- Immune Netw.
- 2004 Sep;4(3):131-142.
- doi: 10.4110/in.2004.4.3.131
In recent years, adjuvants have received much attention because of the development of purified subunit and synthetic vaccines which are poor immunogens and require adjuvants to evoke the immune response.... -
- CITED
-
- Close
- SHARE
-
- Close
- Toll-Like Receptor Ligands as Cancer Immunotherapeutics
-
Lee SE, Rhee JH
- KMID: 1434755
- J Bacteriol Virol.
- 2012 Sep;42(3):255-262.
- doi: 10.4167/jbv.2012.42.3.255
Toll-like receptors (TLRs) are pattern recognition receptors (PRRs) expressed in a wide spectrum of cell types that recognize distinctive ligands and subsequently activate adaptive immune responses. TLR ligands are considered... -
- CITED
-
- Close
- SHARE
-
- Close
- Polyionic vaccine adjuvants: another look at aluminum salts and polyelectrolytes
-
Powell BS, Andrianov , Fusco PC
- KMID: 2049105
- Clin Exp Vaccine Res.
- 2015 Jan;4(1):23-45.
- doi: 10.7774/cevr.2015.4.1.23
Adjuvants improve the adaptive immune response to a vaccine antigen by modulating innate immunity or facilitating transport and presentation. The selection of an appropriate adjuvant has become vital as new... -
- CITED
-
- Close
- SHARE
-
- Close
- New era for mucosal mast cells: their roles in inflammation, allergic immune responses and adjuvant development
-
Kurashima , Kiyono H
- KMID: 2155348
- Exp Mol Med.
- 2014 Mar;46(3):e83.
- doi: 10.1038/emm.2014.7
To achieve immune homeostasis in such a harsh environment as the intestinal mucosa, both active and quiescent immunity operate simultaneously. Disruption of gut immune homeostasis leads to the development of... -
- CITED
-
- Close
- SHARE
-
- Close
- Evaluation of adjuvant effects of fucoidan for improving vaccine efficacy
-
Kim SY, Joo HG
- KMID: 2164522
- J Vet Sci.
- 2015 Jun;16(2):145-150.
- doi: 10.4142/jvs.2015.16.2.145
Fucoidan is a sulfated polysaccharide derived from brown seaweed, including Fucus vesiculosus. This compound is known to have immunostimulatory effects on various types of immune cells including macrophages and dendritic... -
- CITED
-
- Close
- SHARE
-
- Close
- Effects of viscoelastic material on the corneal endothelial cells in trabeculectomy with adjunctive mitomycin-C
-
Shin DB, Lee SB, Kim CS
- KMID: 1037762
- Korean J Ophthalmol.
- 2003 Dec;17(2):83-90.
- doi: 10.3341/kjo.2003.17.2.83
We evaluated the change of corneal endothelium after trabeculectomy with mitomycin-C soaking (0.2 mg/ml, 2.4 +/- 1.2 minutes) and the effect of viscoelastic material in reducing this change. In randomly... -
- CITED
-
- Close
- SHARE
-
- Close
- Dehydroepiandrosterone-dependent induction of peroxisomal proliferation can be reduced by aspartyl esterification without attenuation of inhibitory bone loss in ovariectomy animal model
-
Kwak CS, Kang CM, Kang HS, Song KY, Lee MS, Seong SC, Park SC
- KMID: 965875
- J Korean Med Sci.
- 2000 Oct;15(5):533-541.
- doi: 10.3346/jkms.2000.15.5.533
The purpose of this study was to determine whether esterification of dehydroepiandrosterone with aspartate (DHEA-aspartate) could reduce peroxisomal proliferation induced by DHEA itself, without loss of antiosteoporotic activity. Female Sprague-Dawley... -
- CITED
-
- Close
- SHARE
-
- Close
- Comparison of immunoadjuvant activities of four bursal peptides combined with H9N2 avian influenza virus vaccine
-
Zhang C, Zhou J, Liu Z, Liu Y, Cai K, Shen T, Liao C, Wang C
- KMID: 2427030
- J Vet Sci.
- 2018 Nov;19(6):817-826.
- doi: 10.4142/jvs.2018.19.6.817
The bursa of Fabricius (BF) is a central humoral immune organ unique to birds. Four bursal peptides (BP-I, BP-II, BP-III, and BP-IV) have been isolated and identified from the BF.... -
- CITED
-
- Close
- SHARE
-
- Close
- Dietary germanium biotite supplementation enhances the induction of antibody responses to foot-and-mouth disease virus vaccine in pigs
-
Lee JA, Jung BG, Jung M, Kim TH, Yoo HS, Lee BJ
- KMID: 2155630
- J Vet Sci.
- 2014 Sep;15(3):443-447.
- doi: 10.4142/jvs.2014.15.3.443
We evaluated the potential ability of germanium biotite (GB) to stimulate the production of antibodies specific for foot-and-mouth disease virus (FMDV). To this aim, we measured the total FMDV-specific antibody... -
- CITED
-
- Close
- SHARE
-
- Close
- Checkpoint-inhibition in ovarian cancer: rising star or just a dream?
-
Pietzner K, Nasser S, Alavi S, Darb-Esfahani S, Passler M, Muallem MZ, Sehouli J
- KMID: 2431238
- J Gynecol Oncol.
- 2018 Nov;29(6):e93.
- doi: 10.3802/jgo.2018.29.e93
The introduction of checkpoint inhibitors revolutionized immuno-oncology. The efficacy of traditional immunotherapeutics, like vaccines and immunostimulants was very limited due to persistent immune-escape strategies of cancer cells. Checkpoint inhibitors target... -
- CITED
-
- Close
- SHARE
-
- Close
- Postoperative Carcinoembryonic Antigen as a Complementary Tumor Marker of Carbohydrate Antigen 19-9 in Pancreatic Ductal Adenocarcinoma
-
Kim J, Lee YS, Hwang IK, Kang BK, Cho JY, Yoon YS, Han HS, Hwang JH
- KMID: 2133302
- J Korean Med Sci.
- 2015 Mar;30(3):259-263.
- doi: 10.3346/jkms.2015.30.3.259
The role of carcinoembryonic antigen (CEA) in pancreatic cancer remains poorly understood. Therefore, this study aimed to determine whether CEA is complementary to carbohydrate antigen 19-9 (CA19-9) in prognosis prediction... -
- CITED
-
- Close
- SHARE
-
- Close
- Is Intravesical Bacillus Calmette-Guerin Therapy Superior to Chemotherapy for Intermediate-risk Non-muscle-invasive Bladder Cancer?: An Ongoing Debate
-
Han KS, You D, Jeong IG, Kwon T, Hong B, Hong JH, Ahn H, Ahn TY, Kim CS
- KMID: 2133301
- J Korean Med Sci.
- 2015 Mar;30(3):252-258.
- doi: 10.3346/jkms.2015.30.3.252
The objective of this study was to evaluate the risk of recurrence in patients with intermediate-risk non-muscle-invasive bladder cancer (NMIBC) after intravesical instillation with chemotherapeutic agents or Bacillus Calmette-Guerin (BCG)... -
- CITED
-
- Close
- SHARE
-
- Close
- A Novel Recombinant BCG Vaccine Encoding Eimeria tenella Rhomboid and Chicken IL-2 Induces Protective Immunity Against Coccidiosis
-
Wang Q, Chen L, Li J, Zheng J, Cai N, Gong P, Li S, Li H, Zhang X
- KMID: 1792178
- Korean J Parasitol.
- 2014 Jun;52(3):251-256.
A novel recombinant Bacille Calmette-Guerin (rBCG) vaccine co-expressed Eimeria tenella rhomboid and cytokine chicken IL-2 (chIL-2) was constructed, and its efficacy against E. tenella challenge was observed. The rhomboid gene... -
- CITED
-
- Close
- SHARE
-
- Close
- Modulation of Antibody Responses against Gnathostoma spinigerum in Mice Immunized with Crude Antigen Formulated in CpG Oligonucleotide and Montanide ISA720
-
Intapan PM, Hirunpetcharat C, Kularbkaew C, Yutanawiboonchai W, Janwan P, Maleewong
- KMID: 1712215
- Korean J Parasitol.
- 2013 Dec;51(6):637-644.
- doi: 10.3347/kjp.2013.51.6.637
This study aimed to investigate the antibody responses in mice immunized with Gnathostoma spinigerum crude antigen (GsAg) incorporated with the combined adjuvant, a synthetic oligonucleotide containing unmethylated CpG motif (CpG... -
- CITED
-
- Close
- SHARE
-
- Close
- The immune-stimulating peptide WKYMVm has therapeutic effects against ulcerative colitis
-
Kim SD, Kwon S, Lee SK, Kook M, Lee HY, Song KD, Lee HK, Baek SH, Park CB, Bae YS
- KMID: 2154259
- Exp Mol Med.
- 2013 Sep;45(9):e40.
In this study, we examined the therapeutic effects of an immune-stimulating peptide, WKYMVm, in ulcerative colitis. The administration of WKYMVm to dextran sodium sulfate (DSS)-treated mice reversed decreases in body... -
- CITED
-
- Close
- SHARE
-
- Close
- Intragastric gavage with denatonium benzoate acutely induces neuronal activation in the solitary tract nucleus via the vagal afferent pathway
-
Jung HY, Kim W, Yoo DY, Nam SM, Kim JW, Choi JH, Yoon YS, Kim HY, Hwang IK
- KMID: 2070231
- J Vet Sci.
- 2014 Dec;15(4):459-464.
- doi: 10.4142/jvs.2014.15.4.459
Natural toxic substances have a bitter taste and their ingestion sends signals to the brain leading to aversive oral sensations. In the present study, we investigated chronological changes in c-Fos... -
- CITED
-
- Close
- SHARE
-
- Close
- Optimization of Allergen Standardization
-
Jeong KY, Hong CS, Lee JS, Park JW
- KMID: 1777010
- Yonsei Med J.
- 2011 May;52(3):393-400.
- doi: 10.3349/ymj.2011.52.3.393
Preparation of high quality allergen extracts is essential for the diagnosis and immunotherapy of allergic disorders. Standardization of allergen extracts concerns determination of the allergen unit, development of reference material... -
- CITED
-
- Close
- SHARE
-
- Close
