- The Mechanism of White and Brown Adipocyte Differentiation
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Nakagami H
- KMID: 2280709
- Diabetes Metab J.
- 2013 Apr;37(2):85-90.
- doi: 10.4093/dmj.2013.37.2.85
Obesity gives vent to many diseases such as type 2 diabetes, hypertension, and hyperlipidemia, being considered as the main causes of mortality and morbidity worldwide. The pathogenesis and pathophysiology of... -
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- (99m)Tc-MIBI Uptake in a Thyroid Adenoma with Diffuse Adipose Metaplasia
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Paone G, Mazzucchelli L, Peloni G, Fasolini F, Giovanella L
- KMID: 2386162
- Nucl Med Mol Imaging.
- 2016 Dec;50(4):362-364.
- doi: 10.1007/s13139-015-0383-8
A 71-year-old female underwent a (99m)Tc- MIBI scan to characterize a cold nodule (30 mm) of the left thyroid lobe. The nodule showed diffuse uptake and retention of the radiotracer.... -
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- HOXC10 suppresses browning of white adipose tissues
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Ng Y, Tan SX, Chia SY, Tan HY, Gun SY, Sun L, Hong W, Han W
- KMID: 2375022
- Exp Mol Med.
- 2017 Feb;49(2):e292.
- doi: 10.1038/emm.2016.144
Given that increased thermogenesis in white adipose tissue, also known as browning, promotes energy expenditure, significant efforts have been invested to determine the molecular factors involved in this process. Here... -
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- The Role of Adipose Tissue Vasculature in Energy Balance
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Kim HJ, Choi SH, Chun BG, Kim DH
- KMID: 2001494
- J Korean Soc Pediatr Endocrinol.
- 2011 Dec;16(3):139-156.
- doi: 10.6065/jkspe.2011.16.3.139
The prevalence of obesity is rapidly growing throughout the developing and developed world. Given the seriousness of obesity, it critically needs to develop new therapeutic ways to defend against its... -
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- Two Faces of White Adipose Tissue with Heterogeneous Adipogenic Progenitors
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Hwang I, Kim JB
- KMID: 2466496
- Diabetes Metab J.
- 2019 Dec;43(6):752-762.
- doi: 10.4093/dmj.2019.0174
Chronic energy surplus increases body fat, leading to obesity. Since obesity is closely associated with most metabolic complications, pathophysiological roles of adipose tissue in obesity have been intensively studied. White... -
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- Food Intake and Thermogenesis in Adipose Tissue
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Goto T, Kim M, Takahashi , Takahashi , Kawada T
- KMID: 2357088
- Korean J Obes.
- 2016 Sep;25(3):109-114.
- doi: 10.7570/kjo.2016.25.3.109
Brown adipose tissue (BAT) is regarded as a key target for developing interventions to prevent and treat obesity and age-related diseases. In addition, uncoupling pro tein 1 (UCP1) - expressing... -
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- Changes of Lipogenic and Lipolytic Activities Following Repeated Fasting and Refeeding in Rat
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Lee CK, Kim YW
- KMID: 2078200
- Korean J Obes.
- 2005 Mar;14(1):16-21.
BACKGROUND: It is known that repeated fasting and refeeding increase capacity of fat storage in adipose tissue as an adaptive response to fasting. However, the amount of weight gain in... -
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- Eosinophils and Type 2 Cytokine Signaling in Macrophages Support the Biogenesis of Cold-induced Beige Fat
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Jung Y
- KMID: 2168742
- J Bacteriol Virol.
- 2016 Mar;46(1):44-46.
- doi: 10.4167/jbv.2016.46.1.44
Brown adipose generates heat via oxidation of fatty acids by a mitochondrial uncoupling protein 1 (UCP1)-dependent process. In addition, a subpopulation of cells within subcutaneous white adipose tissue, known as... -
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- Induction of thermogenic adipocytes: molecular targets and thermogenic small molecules
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Song NJ, Chang SH, Li DY, Villanueva CJ, Park KW
- KMID: 2388351
- Exp Mol Med.
- 2017 Jul;49(7):e353.
- doi: 10.1038/emm.2017.70
Adipose tissue is a central metabolic organ that controls energy homeostasis of the whole body. White adipose tissue (WAT) stores excess energy in the form of triglycerides, whereas brown adipose... -
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- Quantification of Fat Concentration and Vascular Response in Brown and White Adipose Tissue of Rats by Spectral CT Imaging
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Peng XG, Zhao Z, Chang D, Bai Y, Xu Q, Ju S
- KMID: 2471642
- Korean J Radiol.
- 2020 Feb;21(2):248-256.
- doi: 10.3348/kjr.2019.0111
OBJECTIVE: The purpose of the study was to non-invasively characterize and discriminate brown adipose tissue (BAT) from white adipose tissue (WAT) in rats using spectral computed tomography (CT) with histological... -
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- Morphologic Comparison of Peripheral Nerves in Adipocyte Tissue from db/db Diabetic versus Normal Mice
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Lee KA, Lee NY, Park TS, Jin HY
- KMID: 2418710
- Diabetes Metab J.
- 2018 Apr;42(2):169-172.
- doi: 10.4093/dmj.2018.42.2.169
Present study investigated the morphologic changes of autonomic nerves in the adipose tissue in diabetic animal model. Male obese type 2 diabetic db/db mice and age matched non-diabetic db/m control... -
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- Heterogeneity of white adipose tissue: molecular basis and clinical implications
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Kwok KH, Lam KS, Xu A
- KMID: 2361502
- Exp Mol Med.
- 2016 Mar;48(3):e215.
- doi: 10.1038/emm.2016.5
Adipose tissue is a highly heterogeneous endocrine organ. The heterogeneity among different anatomical depots stems from their intrinsic differences in cellular and physiological properties, including developmental origin, adipogenic and proliferative... -
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- Anti-obesity effects of hot water extract from Wasabi (Wasabia japonica Matsum.) leaves in mice fed high-fat diets
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Yamasaki M, Ogawa T, Wang L, Katsube T, Yamasaki Y, Sun X, Shiwaku K
- KMID: 2313679
- Nutr Res Pract.
- 2013 Aug;7(4):267-272.
The anti-obesity effects of a hot water extract from wasabi (Wasabia japonica Matsum.) leaves (WLE), without its specific pungent constituents, such as allyl-isothiocyanate, were investigated in high fat-diet induced mice.... -
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- Brown Fat and Browning for the Treatment of Obesity and Related Metabolic Disorders
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Kim SH, Plutzky J
- KMID: 2383310
- Diabetes Metab J.
- 2016 Feb;40(1):12-21.
- doi: 10.4093/dmj.2016.40.1.12
Brown fat is a specialized fat depot that can increase energy expenditure and produce heat. After the recent discovery of the presence of active brown fat in human adults and... -
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- A review on gastric leptin: the exocrine secretion of a gastric hormone
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Cammisotto P, Bendayan M
- KMID: 1447448
- Anat Cell Biol.
- 2012 Mar;45(1):1-16.
- doi: 10.5115/acb.2012.45.1.1
A major advance in the understanding of the regulation of food intake has been the discovery of the adipokine leptin a hormone secreted by the adipose tissue. After crossing the... -
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- Skeletal Muscle Thermogenesis and Its Role in Whole Body Energy Metabolism
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Periasamy , Herrera JL, Reis FC
- KMID: 2392475
- Diabetes Metab J.
- 2017 Oct;41(5):327-336.
- doi: 10.4093/dmj.2017.41.5.327
Obesity and diabetes has become a major epidemic across the globe. Controlling obesity has been a challenge since this would require either increased physical activity or reduced caloric intake; both... -
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- Bile Acid Receptor Farnesoid X Receptor: A Novel Therapeutic Target for Metabolic Diseases
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Fang S
- KMID: 2385838
- J Lipid Atheroscler.
- 2017 Jun;6(1):1-7.
- doi: 10.12997/jla.2017.6.1.1
Bile acid has been well known to serve as a hormone in regulating transcriptional activity of Farnesoid X receptor (FXR), an endogenous bile acid nuclear receptor. Moreover, bile acid regulates... -
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- A Case of Lipoblastoma
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Ahn BJ, Yoon KS, Kim SW
- KMID: 2086272
- Korean J Dermatol.
- 1999 Dec;37(12):1794-1797.
Lipoblastoma is a rare benign mesenchymal tumor that exhibits a tendency to invade locally but not to metastasize, and develops from embryonic remnants of white fat tissue. We experienced a... -
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- Platelet-Derived Growth Factor Receptor-Positive Pericytic Cells of White Adipose Tissue from Critical Limb Ischemia Patients Display Mesenchymal Stem Cell-Like Properties
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Kim EJ, Seo SG, Shin HS, Lee DJ, Kim JH, Lee DY
- KMID: 2412295
- Clin Orthop Surg.
- 2017 Jun;9(2):239-248.
- doi: 10.4055/cios.2017.9.2.239
BACKGROUND: The pericytes in the blood vessel wall have recently been identified to be important in regulating vascular formation, stabilization, remodeling, and function. We isolated and identified pericyte-like platelet-derived growth... -
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- Sirt1 as a New Therapeutic Target in Metabolic and Age-Related Diseases
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Lee DH
- KMID: 1730001
- Chonnam Med J.
- 2010 Aug;46(2):67-73.
- doi: 10.4068/cmj.2010.46.2.67
Sirt1 among the mammalian sirtuins has generated intense scientific interest in recent years, mainly because of its effects on longevity, metabolism, and other aging-related processes. Via nicotinamide adenine dinucleotide (NAD)-dependent... -
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