- TDAG51 deficiency promotes oxidative stress-induced apoptosis through the generation of reactive oxygen species in mouse embryonic fibroblasts
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Park ES, Kim J, Ha TU, Choi JS, Hong KS, Rho J
- KMID: 2154254
- Exp Mol Med.
- 2013 Aug;45(8):e35.
Apoptosis has an important role in maintaining tissue homeostasis in cellular stress responses such as inflammation, endoplasmic reticulum stress, and oxidative stress. T-cell death-associated gene 51 (TDAG51) is a member... -
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- Structural modifications of the prostate in hypoxia, oxidative stress, and chronic ischemia
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Thurmond P, Yang JH, Li Y, Lerner LB, Azadzoi KM
- KMID: 2133286
- Korean J Urol.
- 2015 Mar;56(3):187-196.
- doi: 10.4111/kju.2015.56.3.187
PURPOSE: Clinical studies have reported a correlation between pelvic ischemia and voiding dysfunction in elderly men. The aim of this study was to identify and compare prostate structural modifications in... -
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- Relationship of Oxidative Stress in Hepatitis B Infection Activity with HBV DNA and Fibrosis
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Duygu F, Karsen H, Aksoy N, Taskin A
- KMID: 1245250
- Ann Lab Med.
- 2012 Mar;32(2):113-118.
- doi: 10.3343/alm.2012.32.2.113
BACKGROUND: The aim of this study was to evaluate oxidative stress in various clinical forms of hepatitis B infection and to investigate its role in the development of the chronic... -
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- Oxidative Stress and Chronic Allograft Nephropathy
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Ha H, Park J, Kim YS, Endou H
- KMID: 1726167
- Yonsei Med J.
- 2004 Dec;45(6):1049-1052.
- doi: 10.3349/ymj.2004.45.6.1049
Oxidative stress defined as outbalanced generation of reactive oxygen species (ROS) than the existing antioxidative defense mechanisms plays an important role in tissue injury. Ischemia/reperfusion accompanied during organ transplantation is... -
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- Transcriptional mutagenesis by 8-oxodG in alpha-synuclein aggregation and the pathogenesis of Parkinson's disease
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Basu S, Je G, Kim YS
- KMID: 2155433
- Exp Mol Med.
- 2015 Aug;47(8):e179.
- doi: 10.1038/emm.2015.54
Parkinson's disease (PD) is an age-related progressive neurodegenerative disease associated with selective loss of dopaminergic neurons. The characteristic hallmark of the disease is intracytoplasmic proteinacious inclusion bodies called Lewy bodies,... -
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- Phospholipase D is involved in oxidative stress-induced migration of vascular smooth muscle cells via tyrosine phosphorylation and protein kinase C
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Kim J, Min G, Bae YS, Min DS
- KMID: 1380203
- Exp Mol Med.
- 2004 Apr;36(2):103-109.
Oxidative stress has been implicated in mediation of vascular disorders. In the presence of vanadate, H2O2 induced tyrosine phosphorylation of PLD1, protein kinase C-a (PKC-a), and other unidentified proteins in... -
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- N-acetylcysteine protects against cadmium-induced oxidative stress in rat hepatocytes
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Wang J, Zhu H, Liu X, Liu Z
- KMID: 2070234
- J Vet Sci.
- 2014 Dec;15(4):485-493.
- doi: 10.4142/jvs.2014.15.4.485
Cadmium (Cd) is a well-known hepatotoxic environmental pollutant. We used rat hepatocytes as a model to study oxidative damage induced by Cd, effects on the antioxidant systems, and the role... -
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- Exendin-4 Protects Oxidative Stress-Induced beta-Cell Apoptosis through Reduced JNK and GSK3beta Activity
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Kim JY, Lim DM, Moon CI, Jo KJ, Lee SK, Baik HW, Lee KH, Lee KW, Park KY, Kim BJ
- KMID: 1779233
- J Korean Med Sci.
- 2010 Nov;25(11):1626-1632.
- doi: 10.3346/jkms.2010.25.11.1626
Oxidative stress induced by chronic hyperglycemia in type 2 diabetes plays a crucial role in progressive loss of beta-cell mass through beta-cell apoptosis. Glucagon like peptide-1 (GLP-1) has effects on... -
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- Oxidative Stress Levels in Aqueous Humor from High Myopic Patients
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Kim EB, Kim HK, Hyon JY, Wee WR, Shin YJ
- KMID: 2373972
- Korean J Ophthalmol.
- 2016 Jun;30(3):172-179.
- doi: 10.3341/kjo.2016.30.3.172
PURPOSE: To compare oxidative stress status in the aqueous humor of highly myopic eyes and control eyes. METHODS: Aqueous humor samples were collected from 15 highly myopic eyes (high myopia group)... -
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- Dual effect of oxidative stress on NF-kappaB activation in HeLa cells
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Byun MS, Jeon KI, Choi JW, Shim JY, Jue DM
- KMID: 755204
- Exp Mol Med.
- 2002 Nov;34(5):332-339.
Reactive oxygen species (ROS) has been implicated as an inducer of NF-kappaB activity in numbers of cell types where exposure of cells to ROS such as H2O2 leads to NF-kappaB... -
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- Up-regulation of defense enzymes is responsible for low reactive oxygen species in malignant prostate cancer cells
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Lim HW, Hong S, Jin W, Lim S, Kim SJ, Kang HJ, Park EH, Ahn K, Lim CJ
- KMID: 1089461
- Exp Mol Med.
- 2005 Oct;37(5):497-506.
Reactive oxygen species (ROS) are involved in a diversity of important phenomena in the process of tumor development. To investigate the alterations of oxidative stress and their related systems in... -
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- Oxidative Stress in Vivax Malaria
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Bilgin R, Yalcin MS, Yucebilgic G, Koltas IS, Yazar S
- KMID: 1792135
- Korean J Parasitol.
- 2012 Dec;50(4):375-377.
Malaria is still a leading cause of morbidity and mortality. The increase in lipid peroxidation reported in malaria infection and antioxidant status may be a useful marker of oxidative stress... -
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- Aspartate modulates the ethanol-induced oxidative stress and glutathione utilizing enzymes in rat testes.
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Oh SI, Lee MS, Kim CI, Song KY, Park SC
- KMID: 1093597
- Exp Mol Med.
- 2002 Mar;34(1):47-52.
In order to develop a preventive strategy against ethanol-induced oxidative damages on various tissues and organs, we have examined the protective effect of aspartate on the pathogenesis of testes in... -
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- A Study of Oxidative Stress Parameters in Anti-Helicobacter Pylorus Immunoglobulin G Positive and Negative Gastric Cancer Patients
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Noyan T, Guducuoglu H, Ilhan M
- KMID: 1103822
- Yonsei Med J.
- 2009 Oct;50(5):677-682.
- doi: 10.3349/ymj.2009.50.5.677
PURPOSE: Helicobacter pylorus (HP) is a Gram-negative spiral-shaped microaerophilic bacterium, which colonizes in the gastric mucosa of humans. The gastric human pathogen HP causes chronic gastritis and ulcers, and has... -
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- Biochemical Markers of Oxidative Stress in Saudi Women with Recurrent Miscarriage
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Ghneim HK, Alshebly M
- KMID: 2359998
- J Korean Med Sci.
- 2016 Jan;31(1):98-105.
- doi: 10.3346/jkms.2016.31.1.98
This study was undertaken to investigate the antioxidant/oxidant status in recurrent miscarriage patients. Antioxidants including glutathione peroxidase (GPx), catalase (CAT), glutathione reductase (GR), reduced glutathione (GSH) and selenium (Se), as... -
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- Biliverdin reductase A in the prevention of cellular senescence against oxidative stress
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Kim SY, Kang HT, Choi HR, Park SC
- KMID: 991619
- Exp Mol Med.
- 2011 Jan;43(1):15-23.
- doi: 10.3858/emm.2011.43.1.002
Biliverdin reductase A (BLVRA), an enzyme that converts biliverdin to bilirubin, has recently emerged as a key regulator of the cellular redox cycle. However, the role of BLVRA in the... -
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- The p38 mitogen-activated protein kinase is involved in stress-induced phospholipase D activation in vascular smooth muscle cells
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Min DS, Shin EY, Kim EG
- KMID: 1093596
- Exp Mol Med.
- 2002 Mar;34(1):38-46.
Oxidative stress has been implicated in mediation of vascular disorders. Earlier study showed that the exposure of vascular smooth muscle cells (VSMC) to pervanadate (hydrogen peroxide plus orthovanadate) resulted in... -
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- Endothelial Progenitor Cells Correlated with Oxidative Stress after Mild Traumatic Brain Injury
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Huang X, Wan D, Lin Y, Xue N, Hao J, Ma N, Pei X, Li R, Zhang W
- KMID: 2418939
- Yonsei Med J.
- 2017 Sep;58(5):1012-1017.
- doi: 10.3349/ymj.2017.58.5.1012
PURPOSE: Endothelial progenitor cells (EPCs) play a key role in tissue repair and regeneration. Previous studies have shown that infusion of human umbilical cord blood-derived endothelial colony-forming cells improves outcomes... -
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- Clusterin protects H9c2 cardiomyocytes from oxidative stress-induced apoptosis via Akt/GSK-3beta signaling pathway
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Jun HO, Kim DH, Lee SW, Lee HS, Seo JH, Kim JH, Kim JH, Yu YS, Min BH, Kim KW
- KMID: 991623
- Exp Mol Med.
- 2011 Jan;43(1):53-61.
- doi: 10.3858/emm.2011.43.1.006
Clusterin is a secretory glycoprotein, which is highly up-regulated in a variety of normal and injury tissues undergoing apoptosis including infarct region of the myocardium. Here, we report that clusterin... -
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- Protective Effect of Heat Shock Protein 70 Against Oxidative Stresses in Human Corneal Fibroblasts
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Kim YS, Han JA, Cheong TB, Ryu JC, Kim JC
- KMID: 2157691
- J Korean Med Sci.
- 2004 Aug;19(4):591-597.
- doi: 10.3346/jkms.2004.19.4.591
We evaluated DNA protection effect of heat shock protein (HSP) against cytotoxic effects of exogenous nitric oxide (NO) and reactive oxygen intermediate (ROI). Cultured human corneal fibroblasts were divided into... -
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