Korean J Otorhinolaryngol-Head Neck Surg.  2019 Dec;62(12):755-759. 10.3342/kjorl-hns.2019.00493.

A Case of Head and Neck Mucosa-Associated Lymphoid Tissue Lymphoma Presenting as Progressive Multiple Cranial Nerve Palsy

Affiliations
  • 1Department of Otolaryngology-Head and Neck Surgery, Busan, Korea. chaos001@hanmail.net
  • 2Department of Pathology, College of Medicine, Dong-A University, Busan, Korea.

Abstract

Lymphoma is a malignant tumor arising from the lymphoid tissue. Chronic inflammation can make lymphocyte accumulation and proliferation in the mucous membrane. Sustained accumulation of these persistent changes in the lymphoid tissues may be responsible for the development of mucosa-associated lymphoid tissue (MALT) lymphoma. Although multiple cranial nerve palsy have been reported in various lymphoma, it has never been reported in MALT lymphoma. A 39-year-old man reported of facial palsy and subsequent vocal fold palsy. MALT lymphoma was diagnosed as involving the parotid gland, nasopharynx, and the skull base. Vocal palsy and facial palsy were successfully recovered after chemotherapy.

Keyword

Cranial nerve; Facial paralysis; MALT lymphoma; Vocal fold palsy

MeSH Terms

Adult
Cranial Nerve Diseases*
Cranial Nerves*
Drug Therapy
Facial Paralysis
Head*
Humans
Inflammation
Lymphocytes
Lymphoid Tissue
Lymphoma
Lymphoma, B-Cell, Marginal Zone*
Mucous Membrane
Nasopharynx
Neck*
Paralysis
Parotid Gland
Skull Base
Vocal Cord Paralysis
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