J Korean Orthop Assoc.  1979 Sep;14(3):572-578. 10.4055/jkoa.1979.14.3.572.

Clinical Analysis of Rickets

Abstract

Rickets is a syndrome of diverse etiology, characterized pathophysiologically by a failure of normal mineralization of bone and epiphyseal cartilage and clinically by skeletal deformities. Since the introduction of Vitamin D into the food supply of developed countries, nutritional Vitamin D defiency rickets has become an uncommon disease. In the developing countries Vitamin D deficient rickets occurs not uncommonly, however, and resultant skeletal disorders are still found infrequently. Recently, theories of Vitamin D metabolism have explained the rachitic syndrome, and many of the mystries of the calcium regulatory mechanism have also been uncovered. From January 1971 to May 1975 thirty-two patients with rickets were observed at Yonsei University Severance Hospital. These cases are analysed with a review of the literature. Following observations were made: Of the 32 patients, 14(43.8%) occured between 2 and 3 years of age. 2. The incidence in females was greater than in males (males 28%, females 72%). 3. Bow leg deformity was a major complaint and presenting physical finding. The enlargement of a joint was next. 4. The amelioration of laboratory values and radiological changes were revealed after 2 weeks from the initial treatment. 5. Brace was effective for tibial torsion and was combined with the process of medical treatment.


MeSH Terms

Braces
Calcium
Congenital Abnormalities
Developed Countries
Developing Countries
Female
Food Supply
Genu Varum
Growth Plate
Humans
Incidence
Joints
Male
Metabolism
Miners
Rickets*
Vitamin D
Calcium
Vitamin D
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