- Feasibility of Establishing a Common Cut-Off of Human Leukocyte Antigen Flow Cytometry Crossmatch Using Harmonized Protocols in a Multicenter Setting
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Bang HI, Park Y, Song EY, Oh EJ, Lee JH, Kang ES
- KMID: 2538679
- Lab Med Qual Assur.
- 2022 Dec;44(4):204-211.
- doi: 10.15263/jlmqa.2022.44.4.204
Background: The results of human leukocyte antigen flow cytometry crossmatch (FCXM) are widely used when making transplant decisions. However, standardization/harmonization is required because the results vary between laboratories. A harmonized... -
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- Analysis of antibody responses after COVID-19 vaccination in liver transplant recipients: a single center study
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Oh YJ, Kim JM, Choi GS, Rhu J, Joh JW, Kang ES
- KMID: 2535560
- Korean J Transplant.
- 2022 Nov;36(Supple 1):S333.
- doi: 10.4285/ATW2022.F-4766
Background: Liver transplant (LT) recipients are considered a vulnerable population during the COVID-19 pandemic. The clin-ical efficacy of the COVID-19 vaccine is unknown in immunocompromised patients. The purpose of this... -
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- Fibrotic Burden Determines Cardiovascular Risk among Subjects with Metabolic Dysfunction-Associated Fatty Liver Disease
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Han E, Lee Yh, Lee JS, Lee HW, Kim BK, Park JY, Kim DY, Ahn SH, Lee BW, Kang ES, Cha BS, Kim SU
- KMID: 2533187
- Gut Liver.
- 2022 Sep;16(5):786-797.
- doi: 10.5009/gnl210290
Background/Aims: Metabolic dysfunction associated fatty liver disease (MAFLD) has recently been introduced to compensate for the conventional concept of nonalcoholic fatty liver disease (NAFLD). We explored whether fibrotic burden determines... -
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- Sodium Glucose Cotransporter-2 Inhibitors as an Add-on Therapy to Metformin Plus Dipeptidyl Peptidase-4 Inhibitor in Patients with Type 2 Diabetes
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Bae J, Kim Ye, Lee M, Lee Yh, Lee BW, Cha BS, Kang ES
- KMID: 2530374
- Yonsei Med J.
- 2022 Jun;63(6):539-544.
- doi: 10.3349/ymj.2022.63.6.539
Purpose: To date, no study has compared the effects of adding sodium glucose cotransporter-2 (SGLT-2) inhibitors to the combination of metformin plus dipeptidyl peptidase-4 (DPP-4) inhibitors to the effects of... -
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- Severity-Adjusted Dexamethasone Dosing and Tocilizumab Combination for Severe COVID-19
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Hong JY, Ko JH, Yang J, Ha S, Nham E, Huh K, Cho SY, Kang CI, Chung DR, Baek JY, Sohn YM, Park HJ, Lee B, Huh HJ, Kang ES, Suh GY, Chung CR, Peck KR
- KMID: 2529388
- Yonsei Med J.
- 2022 May;63(5):430-439.
- doi: 10.3349/ymj.2022.63.5.430
Purpose: Real-world experience with tocilizumab in combination with dexamethasone in patients with severe coronavirus disease (COVID-19) needs to be investigated. Materials and Methods: A retrospective cohort study was conducted to evaluate... -
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- Change from Anti-e to Anti-E+c Produced by Donor B Lymphocytes After ABO-incompatible Hematopoietic Stem Cell Transplantation: A Case Report
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Suh E, Choi S, Seo Y, Kang ES, Cho D
- KMID: 2538598
- Lab Med Online.
- 2022 Apr;12(2):138-141.
- doi: 10.47429/lmo.2022.12.2.138
Unexpected red blood cell alloantibodies are relatively uncommon in patients who undergo hematopoietic stem cell transplantation (HSCT). Little is known about the origin of the immune cells responsible for the... -
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- Cardiovascular Risk Is Elevated in Lean Subjects with Nonalcoholic Fatty Liver Disease
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Kim Y, Han E, Lee JS, Lee HW, Kim BK, Kim MK, Kim HS, Park JY, Kim DY, Ahn SH, Lee BW, Kang ES, Cha BS, Lee Yh, Kim SU
- KMID: 2527001
- Gut Liver.
- 2022 Mar;16(2):290-299.
- doi: 10.5009/gnl210084
Background/Aims: Nonalcoholic fatty liver disease (NAFLD) and obesity are independently associated with an increased risk for atherosclerotic cardiovascular disease (ASCVD), the leading cause of mortality in patients with NAFLD. Many... -
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- Multicenter Verification of a Harmonized Test Method for Human Leukocyte Antigen Flow Cytometry Crossmatching
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Park Y, Park MH, Park BG, Oh EJ, Bang HI, Lee JH, Kang ES
- KMID: 2520823
- Lab Med Qual Assur.
- 2021 Sep;43(3):152-161.
- doi: 10.15263/jlmqa.2021.43.3.152
Background: Flow cytometry crossmatch (FCXM) is the most sensitive method currently used for human leukocyte antigen (HLA) crossmatches. The FCXM test methods and cut-off values used to determine the positive reaction... -
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- Anti-Saccharomyces cerevisiae Antibody in Pediatric Crohn’s Disease Patients without Mucosal Healing Is a Useful Marker of Mucosal Damage
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Kim MJ, Kim E, Kang B, Lee Y, Kang ES, Choe YH
- KMID: 2520128
- Gut Liver.
- 2021 Sep;15(5):763-770.
- doi: 10.5009/gnl20212
Background/Aims: We evaluated whether anti-Saccharomyces cerevisiae antibody (ASCA) titers are associated with diagnostic findings, disease activity, Paris classification phenotypes, and persistence after infliximab (IFX) treatment in children with Crohn’s disease... -
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- Non-Laboratory-Based Simple Screening Model for Nonalcoholic Fatty Liver Disease in Patients with Type 2 Diabetes Developed Using Multi-Center Cohorts
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Kim J, Lee M, Kim SY, Kim JH, Nam JS, Chun SW, Park SE, Kim KJ, Lee Yh, Nam JY, Kang ES
- KMID: 2519670
- Endocrinol Metab.
- 2021 Aug;36(4):823-834.
- doi: 10.3803/EnM.2021.1074
Background: Nonalcoholic fatty liver disease (NAFLD) is the most prevalent cause of chronic liver disease worldwide. Type 2 diabetes mellitus (T2DM) is a risk factor that accelerates NAFLD progression, leading... -
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- Effect of pregabalin on nociceptive thresholds and immune responses in a mouse model of incisional pain
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Park JH, Cho SH, Kim R, Na SH, Kang Es, Yeom My, Jang Y
- KMID: 2514418
- Korean J Pain.
- 2021 Apr;34(2):185-192.
- doi: 10.3344/kjp.2021.34.2.185
Background: It is known that some analgesics as well as pain can affect the immune system. The aim of this study was to investigate the analgesic effect and immunomodulation of... -
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- The Usefulness of Flow Cytometry for Measuring Phosphorylated Signal Transducer and Activator of Transcription 1 to Diagnose and Manage Chronic Mucocutaneous Candidiasis: A Case Report
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Yoon SJ, Kwon WK, Jeong M, Yeon JH, Huh HJ, Lee NY, Kim YJ, Kang ES
- KMID: 2512275
- Lab Med Online.
- 2020 Oct;10(4):334-339.
- doi: 10.47429/lmo.2020.10.4.334
Autosomal dominant chronic mucocutaneous candidiasis (AD-CMC) is a subtype of CMC caused by gain-of-function (GOF) mutation of the signal transducer and the activator of transcription 1 (STAT1) protein. GOF mutation... -
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- Pre-Transplant Angiotensin II Type 1 Receptor Antibodies and Anti-Endothelial Cell Antibodies Predict Graft Function and Allograft Rejection in a Low-Risk Kidney Transplantation Setting
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Yu S, Huh HJ, Lee KW, Park JB, Kim SJ, Huh W, Jang HR, Kwon GY, Moon HH, Kang ES
- KMID: 2502570
- Ann Lab Med.
- 2020 Sep;40(5):398-408.
- doi: 10.3343/alm.2020.40.5.398
Background: Non-HLA antibodies, anti-angiotensin II type 1 receptor antibodies (anti-AT1R) and anti-endothelial cell antibodies (AECA), are known to play a role in allograft rejection. We evaluated the role of both... -
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- Hematopoietic Stem Cell Registry Report: 2018
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Kang ES, Lim CS, Han KS, Kim DW
- KMID: 2505396
- Korean J Blood Transfus.
- 2020 Aug;31(2):109-118.
- doi: 10.17945/kjbt.2020.31.2.109
Background: Hematopoietic stem cell (HSC) transplantation is an important therapeutic option for many malignant and non-malignant diseases. The whole transplant process involves multiple areas and complex steps. The laboratory procedures... -
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- Analysis of the Change in Seropositive Rate of the Epstein-Barr Virus in Koreans: A Single-Center Study
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Kim SK, Choi JS, Kim D, Kang CI, Chung DR, Peck KR, Kang ES, Kim YJ
- KMID: 2506229
- Pediatr Infect Vaccine.
- 2020 Aug;27(2):117-126.
- doi: 10.14776/piv.2020.27.e18
Purpose: Epstein-Barr virus (EBV) infection is related to infectious mononucleosis or nasopharyngeal cancer, and its epidemiology may change according to the socioeconomic development of communities. This study aimed to evaluate... -
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- Successful Sirolimus Treatment for Korean Patients with Activated Phosphoinositide 3-kinase δ Syndrome 1: the First Case Series in Korea
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Kang JM, Kim SK, Kim D, Choi SR, Lim YJ, Kim SK, Park BK, Park WS, Kang ES, Ko YH, Choe YH, Lee JW, Kim YJ
- KMID: 2502235
- Yonsei Med J.
- 2020 Jun;61(6):542-546.
- doi: 10.3349/ymj.2020.61.6.542
Activated phosphoinositide 3-kinase δ syndrome (APDS)1 is caused by gain-of-function mutations in PIK3CD, which encodes the catalytic p110δ subunit of phosphoinositide 3 kinase. We describe three patients with APDS1, the... -
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- Association between Non-Alcoholic Steatohepatitis and Left Ventricular Diastolic Dysfunction in Type 2 Diabetes Mellitus
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Lee H, Kim G, Choi YJ, Huh BW, Lee BW, Kang ES, Cha BS, Lee EJ, Lee Yh, Huh KB
- KMID: 2502408
- Diabetes Metab J.
- 2020 Apr;44(2):267-276.
- doi: 10.4093/dmj.2019.0001
Background: Impaired diastolic heart function has been observed in persons with non-alcoholic fatty liver disease (NAFLD) and/or with type 2 diabetes mellitus (T2DM). However, it is unclear whether NAFLD fibrotic... -
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- Comparison of Mac-2 Binding Protein Glycosylation Isomer, Fibroscan, and Other Fibrosis Markers for Assessing Liver Cirrhosis in Patients with Chronic Hepatitis B Virus-mediated Hepatocellular Carcinoma
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Lee K, Yoo IY, Joh JW, Kim JM, Gwak GY, Sinn DH, Ha SY, Kang ES, Park HD
- KMID: 2512240
- Lab Med Online.
- 2020 Apr;10(2):109-115.
- doi: 10.3343/lmo.2020.10.2.109
Background Liver cirrhosis is advanced stage of hepatic brosis caused by viral hepatitis. Mac-2 binding protein glycosylation isomer (M2BPGi) is a serum marker to diagnose and evaluate hepatic brosis progression. In... -
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- Comparative evaluation of QuantiFERON-TB Gold Plus for diagnosis of latent tuberculosis infection during solid organ transplantation
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Yoon SJ, Kwon WK, Jeong MJ, Lee J, Oh HY, Huh W, Jang HR, Joh JW, Kim JM, Choi GS, Kim SJ, Park JB, Lee KW, Sinn DH, Choi JO, Kang ES
- KMID: 2503777
- Korean J Transplant.
- 2020 Mar;34(1):8-14.
- doi: 10.4285/kjt.2020.34.1.8
Background: The diagnosis of latent tuberculosis infection (LTBI) in solid organ transplantation (SOT) patients under lifelong immunosuppression has profound effects on preoperative and postoperative management. Interferon-gamma release assay (IGRA) is... -
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- Flow Cytometry for the Diagnosis of Primary Immunodeficiency Diseases: A Single Center Experience
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Kwon WK, Choi S, Kim HJ, Huh HJ, Kang JM, Kim YJ, Yoo KH, Ahn K, Cho HK, Peck KR, Jang JH, Ki CS, Kang ES
- KMID: 2468463
- Allergy Asthma Immunol Res.
- 2020 Mar;12(2):292-305.
- doi: 10.4168/aair.2020.12.2.292
PURPOSE: While there is an urgent need for diagnosis and therapeutic intervention in patients with primary immunodeficiency diseases (PIDs), current genetic tests have drawbacks. We retrospectively reviewed the usefulness of... -
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