Acute Crit Care.  2018 May;33(2):110-113. 10.4266/acc.2016.00444.

Anterograde Amnesia after Acute Glufosinate Ammonium Intoxication

  • 1Department of Emergency Medicine, Ajou University School of Medicine, Suwon, Korea.


Glufosinate ammonium (GA) intoxication causes several neurologic complications. We report a rare but typical case of GA intoxication associated with anterograde amnesia and bilateral hippocampal involvement. A 53-year-old woman with GA intoxication presented to the emergency department. Initial general and neurologic examinations were unremarkable but, from the day after admission, she exhibited anterograde amnesia. On brain magnetic resonance imaging, the signal intensity in the hippocampus was symmetrically and bilaterally increased. She was discharged with no medical problems, but the anterograde amnesia remained. Eleven days after the onset of amnesia, she returned to the neurology outpatient department with persisting anterograde amnesia but improving symptoms.


ammonia; amnesia; herbicides; hippocampus

MeSH Terms

Ammonium Compounds*
Amnesia, Anterograde*
Emergency Service, Hospital
Magnetic Resonance Imaging
Middle Aged
Neurologic Examination


  • Figure 1. Brain magnetic resonance imaging (MRI) on the sixth day following glufosinate ammonium intoxication. Brain MRI revealed symmetric and bilateral increases in signal intensity in the hippocampus on (A) T2-weighted images and (B) fluid-attenuated inversion recovery images. This lesion exhibited hyperintensity on (C) diffusion-weighted imaging and hypointensities on (D) apparent diffusion coefficient mapping.


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