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Characteristics of Acute Herbicide Poisoning: Focused on Chlorophenoxy Herbicide

Song H, Choi S, Jung YS, Park E, Kim H

PURPOSE: Herbicide-related mortality has decreased since the complete ban of paraquat product sales in 2012, but there still have been other herbicides intoxications with relatively severe complications. Glyphosate and glufosinate...
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A Case of Treatment with QRS Widening in Electrocardiogram after Glyphosate Herbicide Poisoning

Lee JH

Glyphosate herbicides, which are widely used worldwide, are known to have low toxicity. However, excessive intake may cause serious life-threatening complications; therefore, caution is needed when using them. A 51-year-old...
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Comparison of Mortality Rate according to Hospital Level among Patients with Poisoning Based on Korean Health Insurance and Assessment Service

Kim S, Choi S, Kim HH, Yang HW, Yoon S

PURPOSE: Mortality rate in the health services research field is frequently considered as a proxy for measuring healthcare quality. We compared the mortality rate and hospitalization levels among patients with...
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Comparison of Clinical Characteristics and Severity of Glyphosate and Glufosinate Herbicide Poisoning Patients

Joo HS, Yoo TH, Cho SH

PURPOSE: The number of glyphosate and glufosinate intoxication cases are increasing in Korea. This study was undertaken is to compare the clinical manifestations of poisoning by these two herbicides and...
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The Burden of Acute Pesticide Poisoning and Pesticide Regulation in Korea

Ko S, Cha ES, Choi Y, Kim J, Kim JH, Lee WJ

BACKGROUND: This study aimed to estimate the burden of acute pesticide poisoning and to determine its trend with recently implemented pesticide regulations. METHODS: Disability-adjusted life-years (DALYs) were calculated as the sum...
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Relationship between Serum Neuron Specific Enolase Level and Seizure in Patients with Acute Glufosinate Ammonium Poisoning

An GJ, Lee Y, Chan YS, Kim H

PURPOSE: Glufosinate ammonium poisoning can cause seizures, even after a symptom-free period. This study was conducted to evaluate the relationship between serum neuron specific enolase (NSE) level and the occurrence...
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Anterograde Amnesia after Acute Glufosinate Ammonium Intoxication

Kim HH, Min YG

Glufosinate ammonium (GA) intoxication causes several neurologic complications. We report a rare but typical case of GA intoxication associated with anterograde amnesia and bilateral hippocampal involvement. A 53-year-old woman with...
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Prognosis of Acute Pancreatitis in Glyphosate Surfactant Herbicide-intoxicated Patients

Song I, Cha SY, Kang MJ, Kim YH, Lee JH, Cho KW, Hwang SY, Lee DW

PURPOSE: Glyphosate herbicides (GHs) are widely used and increasingly associated with poisoning cases. Acute pancreatitis (AP) is among the many complications associated with the toxicity of GHs. We investigated the...
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Effects of Paraquat Ban on Herbicide Poisoning-Related Mortality

Ko DR, Chung SP, You JS, Cho S, Park Y, Chun B, Moon J, Kim H, Kim YH, Kim HJ, Lee KW, Choi S, Park J, Park JS, Kim SW, Seo JY, Park HY, Kim SJ, Kang H, Hong DY, Hong JH

PURPOSE: In Korea, registration of paraquat-containing herbicides was canceled in November 2011, and sales thereof were completely banned in November 2012. We evaluated the effect of the paraquat ban on...
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Utility of the APACHE II Score as a Neurologic Prognostic Factor for Glufosinate Intoxicated Patients

Yoo DH, Lee JW, Choi JH, Jeong DK, Lee DW, Lee YJ, Cho YS, Park JB, Chung HJ, Moon HJ

PURPOSE: The incidence of glufosinate poisoning is gradually increasing, and it can be fatal if severe poisoning occurs. However, factors useful for predicting the post-discharge neurological prognosis of patients who...
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Clinical Characteristics of Patients after Aryloxyphenoxy Propionate Herbicide Ingestion

Lim J, Moon J, Chun B

PURPOSE: No studies have been conducted to investigate the acute toxicity of aryloxyphenoxypropionate herbicides in humans following ingestion. Therefore, this study was conducted to investigate the clinical characteristics of aryloxyphenoxypropionate...
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Predicting Acute Intoxication of Glufosinate-containing Herbicides: A Comparative Study of a Group with Complication Versus the Others without Complication in Single Institution

Kim YK, Kim KH, Moon HJ, Jeong DK, Lee DW, Park SH, Lee JW

PURPOSE: Glufosinate-containing herbicides intoxication causes mild to severe complication, depending on patients' factors. However, it is not clearly known whether there are factors affecting glufosinate-containing herbicides intoxicated patients who develop...
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Differences in the clinical manifestations and short-term prognosis of acute cerebral infarction after exposure to Agent Orange

Han S, Hwang I, Kim SM, Yang YS, Ha S, Han JH, Park TH

BACKGROUND: Agent Orange (AO) is the code name for one of the herbicides and defoliants used in the Vietnam War. Studies conducted thus far show a significant correlation between AO...
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Paraquat Induces Apoptosis through a Mitochondria-Dependent Pathway in RAW264.7 Cells

Jang YJ, Won JH, Back MJ, Fu Z, Jang JM, Ha HC, Hong S, Chang M, Kim DK

Paraquat dichloride (N,N-dimethyl-4-4'-bipiridinium, PQ) is an extremely toxic chemical that is widely used in herbicides. PQ generates reactive oxygen species (ROS) and causes multiple organ failure. In particular, PQ has...
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A Case of Anterograde Amnesia with Bilateral Hippocampus Involvement After Acute Glufosinate Ammonium Intoxication

Youn SW, Kim HK, Lee HJ

A 51-year-old man developed anterograde amnesia following the ingestion of glufosinate ammonium. Brain MRI revealed hyperintense lesions involving the bilateral hippocampus and parahippocampal gyrus, and the right occipital lobe. The...
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Diagnostic and Therapeutic Approach for Acute Paraquat Intoxication

Gil HW, Hong JR, Jang SH, Hong SY

Paraquat (PQ) has known negative human health effects, but continues to be commonly used worldwide as a herbicide. Our clinical data shows that the main prognostic factor is the time...
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Encephalopathy After Glufosinate Ammonium Intoxication

Kim JH, Yu I, Kim YD, Na SJ, Lee KO, Yoon B

  • KMID: 2191165
  • J Korean Neurol Assoc.
  • 2014 May;32(2):113-116.
Glufosinate ammonium is the active ingredient in broad-spectrum contact herbicides such as BASTA(R) that inhibits the activity of glutamine synthetase, which is necessary for the production of the amino acid...
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A Patient with "Rebound Methemoglobinemia" during Treatment of Methemoglobinemia Caused by Propanil Intoxication

Seon KH, Park YJ, Cho SH

  • KMID: 2333585
  • J Korean Soc Emerg Med.
  • 2013 Dec;24(6):775-779.
Methemoglobinemia results from the oxidation of ferrous iron (Fe++) to ferric iron (Fe+++) within hemoglobin. It is caused by various etiologies, including the herbicide Propanil. Patients with low levels of...
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The Clinical Feature and Prognostic Factor of Glyphosate Intoxication Patients

Eun HM, Paik JH, Suh JH, Jung JH, Eo EK, Roh HK

  • KMID: 2203667
  • J Korean Soc Clin Toxicol.
  • 2013 Dec;11(2):89-95.
PURPOSE: Glyphosate is widely used and its toxic exposures are not rare. Occasionally, glyphosate intoxication can lead to death. The aim of this study is to analyze clinical findings and...
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Glufosinate Herbicide Intoxication Causing Unconsciousness, Convulsion, and 6th Cranial Nerve Palsy

Park JS, Kwak SJ, Gil HW, Kim SY, Hong SY

Although glufosinate ammonium herbicides are considered safe when used properly, ingestion of the undiluted form can cause grave outcomes. Recently, we treated a 34-yr-old man who ingested glufosinate ammonium herbicide....
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