Neonatal Med.  2018 Aug;25(3):91-95. 10.5385/nm.2018.25.3.91.

Clinical Characteristics, Presentation, and Outcomes of Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension

Affiliations
  • 1Department of Pediatrics, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, Goyang, Korea.
  • 2Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea. kimhans@snu.ac.kr

Abstract

Bronchopulmonary dysplasia-associated pulmonary hypertension (BPD-PH) is increasingly being recognized as a cause of morbidity and mortality in preterm infants. Recently, BPD-PH has also been shown to have additional long-term negative effects on neurodevelopmental outcomes and right ventricular function. Several significant risk factors associated with the development of BPD-PH have been identified. A screening strategy for BPD-PH is needed for infants presenting more than one risk factor. In addition, an early echocardiogram within 14 days of age may be a useful tool to identify infants at high-risk for BPD-PH. We have reviewed recent progress in research concerning clinical characteristics, presentation, and outcomes of BPD-PH and have suggested direction for future studies.

Keyword

Bronchopulmonary dysplasia; Pulmonary hypertension; Risk factors

MeSH Terms

Bronchopulmonary Dysplasia
Humans
Hypertension, Pulmonary*
Infant
Infant, Newborn
Infant, Premature
Mass Screening
Mortality
Risk Factors
Ventricular Function, Right

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