Korean J Clin Microbiol.  1998 Sep;1(1):109-112.

Streptococcal Toxic Shock Syndrome Associated with Intrauterine Fetal Death: A Case Report

• Lee SY
• Lee JS
• Lee MA
• Chung WS
• Kim SJ

Abstract

The group A streptococcus is capable of producing exotoxins that have been linked to a toxic shock-like syndrome. Streptococcal toxic shock syndrome is a rapidly progressive associated with injury to multiple organ systems and a 30-60% mortality rate. These cases are very rare in Korea. We present a case of 32-year-old prenant woman who developed streptococcal toxic shock syndrome following intrauterine fetal death. She manifestated hypotension, shock, increased level of creatinine, disseminated intravascular coagulopathy, liver impairment, renal failure, pulmonary edema and adult respiratory distress syndrome. Blood cultures yielded Streptococcus pyogenes. After 17 hours on admission, she died in spite of massive transfusion, antibiotics therapy and ventilatory support. Clinicians should be alert to the importance of early diagnosis and treatment of this lethal infection.

Keyword

Streptococcal toxic shock syndrome; Intrauterine fetal death; Streptococcus pyogenes

MeSH Terms

Adult
Anti-Bacterial Agents
Creatinine
Early Diagnosis
Exotoxins
Female
Fetal Death*
Humans
Hypotension
Korea
Liver
Mortality
Pulmonary Edema
Renal Insufficiency
Respiratory Distress Syndrome, Adult
Shock
Shock, Septic*
Streptococcus
Streptococcus pyogenes
Anti-Bacterial Agents
Creatinine
Exotoxins