Ann Clin Microbiol.  2017 Sep;20(3):63-66. 10.5145/ACM.2017.20.3.63.

High Prevalence of Rotavirus G4P[6] Genotypes among Neonates in Two Korean Hospitals

• Kim JS
• Kim SM
• Kim HS

• KMID: 2424232
• DOI: http://doi.org/10.5145/ACM.2017.20.3.63

Abstract

BACKGROUND
The introduction of rotavirus vaccines has decreased the prevalence of rotavirus infections and might have changed the distribution of rotavirus genotypes. However, neonates are not eligible for vaccination and, therefore, are at risk for rotavirus infection while in the hospital nursery or neonatal intensive care unit. Our aim was to evaluate the shift of genotypes of group A rotavirus strains among neonates cared for in two geographically distant hospitals in Korea.
METHODS
Analysis of rotavirus P and G genotypes was performed for 63 neonates (27 neonates in Seoul and 36 neonates in Busan) admitted to two hospitals between 2011 and 2013.
RESULTS
Among the 63 tested neonates less than one month of age, 61 (96.8%) were infected with genotype G4P[6].
CONCLUSION
This study identified G4P[6] as the most frequently isolated genotypes among neonates in Korea; therefore, prevention of the G4P[6] genotype should be considered for neonates.

Keyword

Genotype; Neonates; Nursery; Prevention; Rotavirus; Vaccine

MeSH Terms

Genotype*
Humans
Infant, Newborn*
Intensive Care, Neonatal
Korea
Nurseries
Nurseries, Hospital
Prevalence*
Rotavirus Infections
Rotavirus Vaccines
Rotavirus*
Seoul
Vaccination
Rotavirus Vaccines