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A neonate with hyperornithinemia-hyperammonemia-homocitrullinuria syndrome from a consanguineous Pakistani family

Kim YM, Lim HH, Gang MH, Lee YW, Kim SZ, Kim GH, Yoo HW, Ko JM, Chang M

Hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome is a rare autosomal recessive urea cycle disorder. HHH is caused by a deficiency of the mitochondrial ornithine transporter protein, which is encoded by the solute carrier...
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A newborn girl with harlequin ichthyosis genetically confirmed by ABCA12 analysis

Kim J, Ko JM, Shin SH, Kim EK, Kim HS

Harlequin ichthyosis (HI, OMIM #242500) is one of the most severe skin diseases among the autosomal recessive congenital ichthyoses, with high morbidity and mortality, particularly in newborns. Clinically, it is...
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Follow-up of infants with congenital hypothyroidism and low total thyroxine/thyroid stimulating hormone on newborn screen

McCormick , Pitts L, Hughes Z

PURPOSE: Newborn screening (NBS) methods to detect congenital hypothyroidism (CH) vary regarding whether total thyroxine (T4), thyroid stimulating hormone (TSH), or both are measured. Neonates with low T4 and normal...
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Serious Necrotizing Enterocolitis in a Neonate Treated with Octreotide for Congenital Chylothorax

Jo MJ, Kim DH, Kim HS

The somatostatin analog octreotide has recently been introduced in the treatment of infants with chylothorax. The safety profile of octreotide has not been fully evaluated. Octreotide reduces the splanchnic blood...
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Two Cases of Herlyn-Werner-Wunderlich Syndrome in Neonates and Adolescents with Hydrocolpos and Hematocolpometra

Park M, Jeon GH

The Herlyn-Werner-Wunderlich (HWW) syndrome is a rare congenital anomaly that is characterized by the triad of uterus didelphys, obstructed hemivagina and ipsilateral renal agenesis. It is often diagnosed in patient...
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Molecular Epidemiologic Study of a Methicillin-resistant Staphylococcus aureus Outbreak at a Newborn Nursery and Neonatal Intensive Care Unit

Kang HM, Park KC, Lee KY, Park J, Park SH, Lee DG, Kim JH

PURPOSE: This study aimed to investigate the molecular epidemiology of a methicillin-resistant Staphylococcus aureus (MRSA) outbreak at a newborn nursery and neonatal intensive care unit (NICU). METHODS: During the outbreak, from...
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A successful application of adult polymyxin B-immobilized fiber column hemoperfusion to a neonate with septic shock

Kim YA, Kim H, Kim YM, Park SE

Direct hemoperfusion therapy with a polymyxin B-immobilized fiber column (PMX-HP) has been introduced as a therapeutic option for gram negative bacterial septic shock in adults. However, its use in neonates...
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Communicating Bronchopulmonary Foregut Malformation Type III with Pulmonary Sequestration Diagnosed in a Newborn: A Case Report

Kim SK, Choi JW, Kim HK, Sung SI, Chang YS, Park WS

Communicating bronchopulmonary foregut malformation (CBPFM) is a communication between the respiratory and gastrointestinal tracts that can be difficult to differentiate from pulmonary sequestration or H-type tracheoesophageal fistula (TEF) because of...
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A Rare Case of Eosinophilic Gastroenteritis in a Neonate with Fever

Lee M, Choi SY, Chung ML, Lee J, Sung M

Eosinophilic gastroenteritis is a member of eosinophilic gastrointestinal (GI) diseases and is characterized by the accumulation of eosinophils within the GI tract. Common symptoms of eosinophilic gastroenteritis are vomiting, abdominal...
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Successful Treatment in a Newborn Infant with Chylous Ascites and Chylous Hydrocele

Ahn SH, Kim WD, Kim YJ

Chyle only occurs in the peritoneal cavity or around the pericardium through damage to the lymph nodes or improper drainage of the lymph and is characterized by a colostrum-like color...
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Inhaled Iloprost as a First-Line Therapy for Persistent Pulmonary Hypertension of the Newborn

Kim SH, Lee HJ, Kim NS, Park HK

PURPOSE: Persistent pulmonary hypertension of the newborn (PPHN) is a potentially fatal disease. Inhaled iloprost, a stable analogue of prostacyclin, has recently been used as a therapeutic option. However, there...
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Implementation of a Targeted Next-Generation Sequencing Panel for Constitutional Newborn Screening in High-Risk Neonates

Lee H, Lim J, Shin JE, Eun HS, Park MS, Park KI, Namgung R, Lee JS

PURPOSE: Newborn screening (NBS) programs are important for appropriate management of susceptible neonates to prevent serious clinical problems. Neonates admitted to neonatal intensive care units (NICU) are at a potentially...
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Effects of Team-based Problem-based Learning Combined with Smart Education: A Focus on High-risk Newborn Care

Yang SY

PURPOSE: This study was conducted to examine the effects of team-based problem-based learning combined with smart education among nursing students. METHODS: A quasi-experimental non-equivalent control group, pre-posttest design was used. The...
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Iodine Deficiency in Neonates: Where Do We Stand After a Quarter Century of Initiating Iodization Programs?

Jafri L, Majid H, Ahmed S, Siddiqui I, Ghani F, Khan AH

An observational study was conducted at the Section of Clinical Chemistry, Department of Pathology and Laboratory Medicine, to assess the iodine status using the World Health Organization (WHO), United Nations...
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Pneumothorax in Full-term Neonates Transferred due to Respiratory Distress

Kim Y, Lee E

OBJECTIVE: To investigate the incidence and course of pneumothorax in full-term infants with dyspnea. METHODS: We retrospectively reviewed 607 newborn infants who had dyspnea and transferred to the tertiary medical center...
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Comparison of Bilirubin Levels in Neonates with Hyperbilirubinemia according to Delivery Methods

Lee GY, Choi JW

OBJECTIVE: This study aimed to find out the correlation between bilirubin levels and delivery methods in term babies with neonatal hyperbilirubinemia. METHODS: This retrospective study was performed in a single center....
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Effect of Synbiotic on the Treatment of Jaundice in Full Term Neonates: A Randomized Clinical Trial

Ahmadipour S, Baharvand , Rahmani P, Hasanvand , Mohsenzadeh A

PURPOSE: Jaundice accounts for most hospital admissions in the neonatal period. Nowadays, in addition to phototherapy, other auxiliary methods are used to reduce jaundice and the length of hospitalization. This...
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Comparison of Acute Abdominal Surgical Outcomes of Extremely-Low-Birth-Weight Neonates according to Differential Diagnosis

Byun J, Kim HY, Jung SE, Yang HB, Kim EK, Shin SH, Kim HS

BACKGROUND: Improvements in perinatal intensive care have improved survival of extremely-low-birth-weight (ELBW) neonates, although the risk of acute abdomen has increased. The differential diagnosis resulting in abdominal surgery can be...
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Outcome of Neonates with Agenesis of Septum Pellucidum: A Retrospective Single Center Study

Kim YH, Lee YK, Ko SY, Shin SM

PURPOSE: Agenesis of the septum pellucidum (ASP) is a very rare disease that can be isolated or associated with other brain abnormalities. The neurological prognosis of isolated ASP remains controversial....
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Evaluation of Newborn Infants with Prenatally Diagnosed Congenital Pulmonary Airway Malformation: A Single-Center Experience

Lim J, Han JH, Shin JE, Eun HS, Lee SM, Park MS, Namgung R, Park KI

PURPOSE: Congenital pulmonary airway malformation (CPAM)—a rare developmental anomaly—affects the lower respiratory tract in newborns. By comparing the reliability of diagnostic tools and identifying predictive factors for symptoms, we provide...
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