Nucl Med Mol Imaging.  2018 Apr;52(2):109-118. 10.1007/s13139-017-0504-7.

Deep Learning in Nuclear Medicine and Molecular Imaging: Current Perspectives and Future Directions

  • 1Cheonan Public Health Center, Cheonan, Republic of Korea.


Recent advances in deep learning have impacted various scientific and industrial fields. Due to the rapid application of deep learning in biomedical data, molecular imaging has also started to adopt this technique. In this regard, it is expected that deep learning will potentially affect the roles of molecular imaging experts as well as clinical decision making. This review firstly offers a basic overview of deep learning particularly for image data analysis to give knowledge to nuclear medicine physicians and researchers. Because of the unique characteristics and distinctive aims of various types of molecular imaging, deep learning applications can be different from other fields. In this context, the review deals with current perspectives of deep learning in molecular imaging particularly in terms of development of biomarkers. Finally, future challenges of deep learning application for molecular imaging and future roles of experts in molecular imaging will be discussed.


Deep learning; Molecular imaging; Machine learning; Convolutional neural network; Precision medicine

MeSH Terms

Clinical Decision-Making
Machine Learning
Molecular Imaging*
Nuclear Medicine*
Precision Medicine
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