- Yonsei Criteria, a Potential Linkage to Intratumoral Foxp3âº/CD8⺠Ratio for the Prediction of Oncologic Outcomes in Resected Left-Sided Pancreatic Cancer
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Hwang HK, Lee SH, Kim HI, Kim SH, Choi J, Kang CM, Lee WJ
- KMID: 2471914
- Yonsei Med J.
- 2020 Apr;61(4):291-300.
- doi: 10.3349/ymj.2020.61.4.291
PURPOSE: This study sought to investigate associations among Yonsei criteria (tumor confined to the pancreas, intact fascia layer between the distal pancreas and the left adrenal gland and kidney, and... -
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- New Insights on the Mechanisms Affecting Fertility in Men with Non-Seminoma Testicular Cancer before Cancer Therapy
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Dias TR, Agarwal A, Pushparaj , Ahmad G, Sharma R
- KMID: 2471826
- World J Mens Health.
- 2020 Apr;38(2):198-207.
- doi: 10.5534/wjmh.180099
PURPOSE: Patients with non-seminoma testicular cancer (NSTC) cancer can be subfertile or infertile, and present reduced sperm quality, but the underlying mechanisms are unknown. The aim of this study was... -
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- Optimized Image-Based Surrogate Endpoints in Targeted Therapies for Glioblastoma: A Systematic Review and Meta-Analysis of Phase III Randomized Controlled Trials
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Suh CH, Kim HS, Jung SC, Choi CG, Kim SJ, Kim KW
- KMID: 2471813
- Korean J Radiol.
- 2020 Apr;21(4):471-482.
- doi: 10.3348/kjr.2019.0839
OBJECTIVE: We aimed to determine the optimized image-based surrogate endpoints (IBSEs) in targeted therapies for glioblastoma through a systematic review and meta-analysis of phase III randomized controlled trials (RCTs). MATERIALS AND... -
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- Identification of Molecular Signatures in Mild Intrinsic Atopic Dermatitis by Bioinformatics Analysis
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Yin H, Wang S, Gu C
- KMID: 2471339
- Ann Dermatol.
- 2020 Apr;32(2):130-140.
- doi: 10.5021/ad.2020.32.2.130
BACKGROUND: Atopic dermatitis (AD) is recognized as a common inflammatory skin disease and frequently occurred in Asian and Black individuals. OBJECTIVE: Since the limitation of dataset associated with human severe AD,... -
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- Alzheimer's Disease Diagnosis Using Misfolding Proteins in Blood
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Lee H, Ugay D, Hong S, Kim Y
- KMID: 2471931
- Dement Neurocogn Disord.
- 2020 Mar;19(1):1-18.
- doi: 10.12779/dnd.2020.19.1.1
Alzheimer's disease (AD) is pathologically characterized by a long progressive phase of neuronal changes, including accumulation of extracellular amyloid-β (Aβ) and intracellular neurofibrillary tangles, before the onset of observable symptoms.... -
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- The Amniotic Fluid Proteome Differs Significantly between Donor and Recipient Fetuses in Pregnancies Complicated by Twin-to-Twin Transfusion Syndrome
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Kim SM, Cho BK, Kim BJ, Lee HY, Norwitz ER, Kang MJ, Lee SM, Park CW, Jun JK, Yi EC, Park JS
- KMID: 2471801
- J Korean Med Sci.
- 2020 Mar;35(10):e73.
- doi: 10.3346/jkms.2020.35.e73
BACKGROUND: Twin-to-twin transfusion syndrome (TTTS) is a serious complication of monochorionic twin pregnancies. It results from disproportionate blood supply to each fetus caused by abnormal vascular anastomosis within the placenta.... -
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- Can Calprotectin Show Subclinical Inflammation in Familial Mediterranean Fever Patients?
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Asan G, Derin ME, DoÄŸan HO, Bayram M, Åžahin M, Åžahin A
- KMID: 2471797
- J Korean Med Sci.
- 2020 Mar;35(10):e63.
- doi: 10.3346/jkms.2020.35.e63
BACKGROUND: Familial Mediterranean fever (FMF) is an autoinflammatory disease that has self-limiting inflammatory attacks during polyserositis. Hepcidin is a protein, and interleukin-6 stimulation increases hepcidin levels. Calprotectin (CLP) is a... -
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- Protein Expression of Cyclin B1, Transferrin Receptor, and Fibronectin Is Correlated with the Prognosis of Adrenal Cortical Carcinoma
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Moon SJ, Kim JH, Kong SH, Shin CS
- KMID: 2471729
- Endocrinol Metab.
- 2020 Mar;35(1):132-141.
- doi: 10.3803/EnM.2020.35.1.132
BACKGROUND: Adrenal cortical carcinoma (ACC) is a rare cancer with a variable prognosis. Several prognostic factors of ACC have been previously reported, but a proteomic analysis has not yet been... -
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- Potential Biomarkers to Improve the Prediction of Osteoporotic Fractures
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Kim BJ, Lee SH, Koh JM
- KMID: 2471720
- Endocrinol Metab.
- 2020 Mar;35(1):55-63.
- doi: 10.3803/EnM.2020.35.1.55
Osteoporotic fracture (OF) is associated with high disability and morbidity rates. The burden of OF may be reduced by early identification of subjects who are vulnerable to fracture. Although the... -
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- Establishment of patient-derived three-dimensional organoid culture in renal cell carcinoma
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Na JC, Kim JH, Kim SY, Gu YR, Jun DY, Lee HH, Yoon YE, Choi KH, Hong SJ, Han WK
- KMID: 2471078
- Investig Clin Urol.
- 2020 Mar;61(2):216-223.
- doi: 10.4111/icu.2020.61.2.216
PURPOSE: Renal cell carcinoma is a heterogeneous kidney cancer, and over 403,000 cases were reported worldwide in 2018. Current methods for studying renal cell carcinoma are limited to two-dimensional (2D)... -
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- Changes in plasma lipoxin A4, resolvins and CD59 levels after ischemic and traumatic brain injuries in rats
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Jung JS, Kho AR, Lee SH, Choi BY, Kang SH, Koh JY, Suh SW, Song DK
- KMID: 2471038
- Korean J Physiol Pharmacol.
- 2020 Mar;24(2):165-171.
- doi: 10.4196/kjpp.2020.24.2.165
Ischemic and traumatic brain injuries are the major acute central nervous system disorders that need to be adequately diagnosed and treated. To find biomarkers for these acute brain injuries, plasma... -
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- Chinese Society of Allergy and Chinese Society of Otorhinolaryngology-Head and Neck Surgery Guideline for Chronic Rhinosinusitis
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Liu Z, Chen J, Cheng L, Li H, Liu S, Lou H, Shi J, Sun Y, Wang D, Wang C, Wang X, Wei Y, Wen W, Yang P, Yang Q, Zhang G, Zhang Y, Zhao C, Zhu D, Zhu L, Chen F, Dong Y, Fu Q, Li J, Li Y, Liu C, Liu F, Lu M, Meng Y, Sha J, She W, Shi L, Wang K, Xue J, Yang L, Yin M, Zhang L, Zheng M, Zhou B, Zhang L
- KMID: 2468459
- Allergy Asthma Immunol Res.
- 2020 Mar;12(2):176-237.
- doi: 10.4168/aair.2020.12.2.176
The current document is based on a consensus reached by a panel of experts from the Chinese Society of Allergy and the Chinese Society of Otorhinolaryngology-Head and Neck Surgery, Rhinology... -
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- Urinary Biomarkers may Complement the Cleveland Score for Prediction of Adverse Kidney Events After Cardiac Surgery: A Pilot Study
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Albert C, Haase M, Albert A, Kropf S, Bellomo R, Westphal S, Westerman , Braun-Dullaeus RC, Haase-Fielitz A
- KMID: 2460910
- Ann Lab Med.
- 2020 Mar;40(2):131-141.
- doi: 10.3343/alm.2020.40.2.131
BACKGROUND: The ability of urinary biomarkers to complement established clinical risk prediction models for postoperative adverse kidney events is unclear. We assessed the effect of urinary biomarkers linked to suspected... -
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- Radiomics in Lung Cancer from Basic to Advanced: Current Status and Future Directions
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Lee G, Park H, Bak SH, Lee HY
- KMID: 2471633
- Korean J Radiol.
- 2020 Feb;21(2):159-171.
- doi: 10.3348/kjr.2019.0630
Ideally, radiomics features and radiomics signatures can be used as imaging biomarkers for diagnosis, staging, prognosis, and prediction of tumor response. Thus, the number of published radiomics studies is increasing... -
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- Reference Intervals for Bone Turnover Markers in Korean Healthy Women
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Cho DH, Chung JO, Chung MY, Cho JR, Chung DJ
- KMID: 2471313
- J Bone Metab.
- 2020 Feb;27(1):43-52.
- doi: 10.11005/jbm.2020.27.1.43
BACKGROUND: Adequate suppression of bone turnover rate is important to decrease fracture risk without mineralization defect due to oversuppression. This study was performed to determine reference intervals (RIs) for 2... -
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- Immunotherapy for Non-small Cell Lung Cancer: Current Landscape and Future Perspectives
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Lim SM, Hong MH, Kim HR
- KMID: 2471050
- Immune Netw.
- 2020 Feb;20(1):e10.
- doi: 10.4110/in.2020.20.e10
Immune checkpoint inhibitors (ICIs) have shown remarkable benefit in the treatment of patients with non-small-cell lung cancer (NSCLC) and have emerged as an effective treatment option even in the first-line... -
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- Peripheral blood immune cell-based biomarkers in anti-PD-1/PD-L1 therapy
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Kim KH, Kim CG, Shin EC
- KMID: 2471048
- Immune Netw.
- 2020 Feb;20(1):e8.
- doi: 10.4110/in.2020.20.e8
Immune checkpoint blockade targeting PD-1 and PD-L1 has resulted in unprecedented clinical benefit for cancer patients. Anti-PD-1/PD-L1 therapy has become the standard treatment for diverse cancer types as monotherapy or... -
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- Plasma CD36 and Incident Diabetes: A Case-Cohort Study in Danish Men and Women
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Wang Y, Zhu J, Aroner S, Overvad K, Cai T, Yang M, Tjønneland A, Handberg A, Jensen MK
- KMID: 2470962
- Diabetes Metab J.
- 2020 Feb;44(1):134-142.
- doi: 10.4093/dmj.2018.0273
BACKGROUND: Membrane CD36 is a fatty acid transporter implicated in the pathogenesis of metabolic disease. We aimed to evaluate the association between plasma CD36 levels and diabetes risk and to... -
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- Downregulation of N-myc and STAT Interactor Protein Predicts Aggressive Tumor Behavior and Poor Prognosis in Invasive Ductal Carcinoma
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Choi JE, Hyun CL, Jin MS, Lee KM, Moon JH, Ryu HS
- KMID: 2470880
- J Breast Cancer.
- 2020 Feb;23(1):36-46.
- doi: 10.4048/jbc.2020.23.e12
PURPOSE: We investigated the expression of the N-myc and STAT interactor (NMI) protein in invasive ductal carcinoma tissue and estimated its clinicopathologic significance as a prognostic factor. The expression levels... -
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- Predicting the Benefit of Adjuvant Aromatase Inhibitor Therapy in Postmenopausal Breast Cancer Patients with Phosphorylated S6K1 Expression Status
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Choi J, Park CS, Seong MK, Seol H, Kim JS, Park IC, Noh WC, Kim HA
- KMID: 2470878
- J Breast Cancer.
- 2020 Feb;23(1):10-19.
- doi: 10.4048/jbc.2020.23.e5
PURPOSE: Phosphorylated ribosomal S6 kinase 1 (pS6K1) is a major downstream regulator of the mammalian target of rapamycin (mTOR) pathway. Recent studies have addressed the role of S6K1 in adipogenesis.... -
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