Res Vestib Sci.  2018 Jun;17(2):60-66. 10.21790/rvs.2018.17.2.60.

Superficial Siderosis with Peripheral Dizziness: Report of 2 Cases

Affiliations
  • 1Department of Otorhinolaryngology-Head and Neck Surgery, KyungHee University School of Medicine, Seoul, Korea. otorhino512@naver.com

Abstract

Superficial siderosis (SS) of the central nervous system is a rare disease, which is caused by the accumulation of iron from the hemoglobin in the superficial layer of the brain, spinal cord, and central parts of cranial nerves. The etiology of SS is the accumulation of hemosiderin in the subarachnoid space due to chronic or repeated hemorrhage resulting in progressive and irreversible neurological dysfunction. The cause of the disease is aneurysm, trauma, tumor, and vascular malformation. In most cases, the cause of bleeding is unknown. Clinical features include sensorineural hearing loss, cerebellar ataxia, and myelopathy. Until now, magnetic resonance imaging (MRI) has only been diagnosed and there is no standardized treatment. We will investigate clinical features and MRI findings of SS disease in the central nervous system using 2 patient cases.

Keyword

Hemosiderin; Superficial siderosis; Vertigo; Sensorineural hearing loss
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