Allergy Asthma Immunol Res.  2017 Mar;9(2):182-184. 10.4168/aair.2017.9.2.182.

Fixed Food Eruption Caused by Actinidia arguta (Hardy Kiwi): A Case Report and Literature Review

Affiliations
  • 1Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. drmin@snu.ac.kr
  • 2Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center, Seoul National University College of Medicine, Seoul, Korea.
  • 3Seoul National University Hospital Regional Pharmacovigilance Center, Seoul, Korea.

Abstract

Fixed drug eruption (FDE) is a common hypersensitivity reaction characterized by recurrent, well-circumscribed, erythematous patches that arise at the same site as a result of systemic drug exposure. However, fixed food eruption (FFE), a lesion triggered by food ingestion, is a rare allergy that was first defined in 1996. Based on their anti-inflammatory and anti-oxidant properties, the fruit and leaves of Actinidia arguta, the hardy kiwi, are widely consumed across Korea, Japan, and China. This report describes the first case of FFE caused by hardy kiwi leaves, known as Daraesun in Korean, confirmed by oral provocation tests and skin biopsy.

Keyword

Fixed food eruption; actinidia arguta; food allergy

MeSH Terms

Actinidia*
Biopsy
China
Drug Eruptions
Eating
Food Hypersensitivity
Fruit
Hypersensitivity
Japan
Korea
Skin
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