Clin Should Elbow.
2011 Dec;14(2):172-178.
Inflammatory Cytokine Expressions of the Subacromial Bursitis and Glenohumeral Joint Synovitis in the Patients with Full Thickness Rotator Cuff Tear
- Affiliations
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- 1Department of Orthopaedic Surgery, Chonnam National University College of Medicine, Gwangju, Korea. mskim@jnu.ac.kr
Abstract
- PURPOSE
The purpose of this study was to compare expression patterns of inflammatory cytokines between subacromial bursitis and glenohumeral (GH) joint synovitis in full thickness rotator cuff (RC) tear patients with severe pain.
MATERIALS AND METHODS
We were able to obtain enough tissue from nine subacromial bursitis and GH synovitis patients at the same time during surgery and evaluate them. We compared mRNA expression of inflammatory cytokines between the two groups using Reverse Transcription-Polymerase Chain Reaction (RT-PCR).
RESULTS
Relative mean mRNA expression of IL-1beta, IL-6, TNF-alpha, COX-1, COX-2 and SDF-1 in the tissues of subacromial bursitis and GH synovitis patients did not show significant differences.
CONCLUSION
GH synovitis may be another source of shoulder pain with subacromial bursitis in full thickness RC tear patients with severe pain.
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