Korean J Gastroenterol.  2018 Jan;71(1):49-53. 10.4166/kjg.2018.71.1.49.

Angiomyolipoma of the Liver without a Fat Component, Mimicking a Hepatocellular Carcinoma

• Woo YM
• Ryu SH
• Min JW
• Kim MR
• Park TY
• Moon JS
• Kang YK

• KMID: 2402806
• DOI: http://doi.org/10.4166/kjg.2018.71.1.49

Abstract

Angiomyolipoma (AML) is a rare benign mesenchymal tumor in the liver, which is composed of blood vessels, smooth muscle, and adipose cells. The proportion of each component varies, making a diagnosis difficult. This paper reports a case of AML in the liver without adipose tissue, mimicking a hepatocellular carcinoma (HCC), which was diagnosed by a surgical tissue biopsy. A 65-year-old woman was admitted for an evaluation of a hepatic mass that had been detected by ultrasonography. The serologic markers of viral hepatitis B and C were negative. The liver function tests and alpha fetoprotein level were within the normal limits. Magnetic resonance imaging revealed a 1.9 cm sized mass in segment 6 of the liver with early arterial enhancement and washout on the delayed phase accompanied by a rim-like enhancement, which is similar to the imaging findings of HCC. A frozen section examination during surgery indicated a hepatocellular neoplasm and suggested the possibility of HCC. On the other hand, the final pathologic diagnosis was epithelioid myoid type of AML with no adipose tissue component. The tumor cells were positive for human melanocyte B-45 and negative for cytokeratin and hepatocyte paraffin 1. This paper reports a very rare case of AML without adipose tissue in the liver mimicking HCC that was diagnosed by a surgical tissue biopsy.

Keyword

Angiomyolipoma; Liver; Carcinoma, hepatocellular

MeSH Terms

Adipose Tissue
Aged
alpha-Fetoproteins
Angiomyolipoma*
Biopsy
Blood Vessels
Carcinoma, Hepatocellular*
Diagnosis
Female
Frozen Sections
Hand
Hepatitis B
Hepatocytes
Humans
Keratins
Liver Function Tests
Liver*
Magnetic Resonance Imaging
Melanocytes
Muscle, Smooth
Paraffin
Ultrasonography
Keratins
Paraffin
alpha-Fetoproteins