- Some observations on the organelles participating in the biliary excretion in the rat hepatocytes
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Shin YC
- KMID: 1686823
- Korean J Anat.
- 1991 Mar;24(1):3-18.
No abstract available. -
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- Fine Structure and Albumin Gene Expression in Intrasplenically Transplanted Hepatocytes
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Kwon SO, Lee DK, Kim JM, Park ER, Shim KY, Jung PH, Cho MY, Hur MU
- KMID: 2251596
- Korean J Med.
- 1997 Oct;53(4):534-540.
BACKGROUND: The morphological characteristics of hepatocytes transplanted into the spleen have been studied. However few attempts has been made to determine the expression of genes in intrasplenically transplanted hepatocytes. The... -
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- Optimal Number of Hepatocytes per Microcarrier in Spheroid Culture using Cytodex 3 Microcarrier
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Shin WY, Lee KU, Lee HW, Cho EH, Yi NJ, Suh KS
- KMID: 2211102
- J Korean Surg Soc.
- 2007 Sep;73(3):235-241.
PURPOSE: The mass cultivation of functional hepatocytes is a key factor of a bioartificial liver. Combining spheroid and microcarrier cultures has been applied for enhancing the cell viability and metabolic... -
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- Expression of Hepatitis C Virus Core Protein in Hepatocytes Does Not Modulate Proliferation or Apoptosis of CD8+ T Cells
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Jin YH, Crispe IN, Park S
- KMID: 2428300
- Yonsei Med J.
- 2005 Dec;46(6):827-834.
Hepatocytes are the primary targets of the hepatitis C virus (HCV). While immunosuppressive roles of HCV core protein have been found in several studies, it remains uncertain whether core protein... -
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- A Study on Intrasplenic Transplantation of Embryonic Stem Cells
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Choi CS, Yang YC, Choi YK
- KMID: 2145218
- J Korean Surg Soc.
- 2001 May;60(5):549-557.
PURPOSE: The authors evaluated the morphological and proliferative properties of embryonic stem (ES) cells following intrasplenic transplantation. The results were compared with those obtained following intrasplenic transplantation of cultured hepatocytes. METHODS:... -
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- Study of Ex Vivo Growth Characteristics of N-Nitrosomorpholine Treated Rat Hepatocytes
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Kang SS, Kim MC, Jeong JS, Choi YC, Kim SS
- KMID: 1815315
- J Korean Cancer Assoc.
- 2000 Oct;32(5):972-980.
PURPOSE: The early carcinogenic effect of N-nitrosomorpholine (NNM) on acquisition of increased survival and growth was investigated using ex vivo culture of 5th to 10th week rat liver hepatocytes after... -
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- Experimental studies on the hepatic damage after Co-60 irradiation in rats
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Kim YR, Kim CS
- KMID: 2349362
- J Korean Radiol Soc.
- 1979 Jun;15(1):164-171.
- doi: 10.3348/jkrs.1979.15.1.164
In a series of studies to elucidate the direct effect of irradiation on liver, rats we Co-60 irradiated to theright side of liver in a dosage of 600 R. The... -
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- Effect of Long-term Passage on Liver-specific Functions in Immortalized Hepatocytes with a Temperature-sensitive Mutant of SV40 T Antigen
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Kim BH, Seong SR, Lee WI, Dong SH, Kim HJ, Chang YW, Lee JI, Chang R
- KMID: 2304644
- Korean J Gastroenterol.
- 1999 Jul;34(1):56-68.
BACKGROUND/AIMS: The transcription of liver specific genes decreases dramatically in primary hepatocyte culture. In this study, we evaluated the long-term differentiation of immortalized hepatocytes. METHODS: Immortalized rat hepatocytes were established... -
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- Cryopreservation of Primary Hepatocytes for Repeated Investigational Uses
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Dong SH, Kim BH, Sung SR, Kim YI, Park JK, Kim KJ, Kim HJ, Chang YW, Lee JI, Chang R
- KMID: 2240329
- Korean J Gastroenterol.
- 2000 May;35(5):591-599.
BACKGROUND/AIMS: The cryopreservation of primary hepatocytes could avoid unnecessary isolation of hepatocytes and meet repeated investigational demands. We tried to find out an optimal cryopreservation method of rat hepatocytes. METHODS: Primary hepatocytes with... -
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- Effects of Rhodiola Sachalinensis on Nitric Oxide Synthesis by Macrophages, Hepatocytes, and Vascular Smooth Muscle Cells
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Lee HK, Shin MK, Bae HO, Seo WG, Oh GS, Ahn BS, Chung HT
- KMID: 1646433
- Korean J Immunol.
- 2000 Dec;22(4):229-234.
No abstract available. -
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- Successful mouse hepatocyte culture with sandwich collagen gel formation
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Choi HJ, Choi D
- KMID: 2212464
- J Korean Surg Soc.
- 2013 Apr;84(4):202-208.
- doi: 10.4174/jkss.2013.84.4.202
PURPOSE: Primary mammalian hepatocytes largely retain their liver-specific functions when they are freshly derived from donors. However, long-term cultures of functional hepatocytes are difficult to establish. To increase the longevity... -
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- Effects of glucose concentration in the medium on rat hepatocyte culture
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Na GH, Kim DG, Kim YH, Han JH, Jung ES
- KMID: 1882831
- Ann Surg Treat Res.
- 2014 Aug;87(2):53-60.
- doi: 10.4174/astr.2014.87.2.53
PURPOSE: To determine the optimum culture conditions by investigating isolated rat hepatocytes cultured in medium containing different glucose concentrations. METHODS: Hepatocytes were isolated from rats using a two-step perfusion technique and... -
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- Hepatocytes isolation from UW preserved rat liver
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Lee KW, Suh KS, Roh HR, Koh YT, Lee KU
- KMID: 2083179
- Korean J Hepatobiliary Pancreat Surg.
- 2001 Jul;5(1):27-34.
BACKGROUND/AIMS: In the immunological and functional aspects, freshly isolated human hepatocytes are better than animal hepatocytes from other species such as the pig and hepatocytes from human tumor cell lines.... -
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- Freezing and Thawing Conditions of Rat Hepatocytes
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Hwang SG, Jung EM, Oh SW, Kwon CI, Kim KC, Hong SP, Park PW, Rim KS
- KMID: 1890007
- Korean J Hepatol.
- 2001 Sep;7(3):308-314.
BACKGROUND/AIMS: During cryopreservation of hepatocytes, a dramatic loss in cell number, viability and differentiated cell function is usually inevitable because hepatocytes are very sensitive to stress during freezing and thawing.... -
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- Biodistribution of Intrasplenically Transplanted Hepatocytes in the Rat
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Kim WH, Lee JH, Jin YM, Park HL, Kim BH, Han SU, Wang HJ, Kim MW
- KMID: 2095362
- J Korean Surg Soc.
- 1998 Jun;54(6):772-779.
Liver failure still constitutes a major cause of morbidity and death in patients with liver disease. Various potential treatments have been discussed to reduce liver failure-induced deaths. Recently, interest in... -
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- Effect of Intrasplenic Transplantation of Cryopreserved Hepatocytes into Partially Hepatectomized Rats
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Hwang SG, Yun IJ, Kim YS, Kim KC, Hong SP, Park PW, Rim KS, Cho JY, Lee JS, Lee MS, Shim CS
- KMID: 2241323
- Korean J Hepatol.
- 1999 Jun;5(2):116-123.
BACKGROUND/AIMS: Various techniques of hepatocyte transplantation were actively studied as an alternative to liver transplantation, because of the difficulty of obtaining donor organ, technical difficulties, and high cost. Isolated hepatocytes could be appropriately... -
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- N-acetylcysteine protects against cadmium-induced oxidative stress in rat hepatocytes
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Wang J, Zhu H, Liu X, Liu Z
- KMID: 2070234
- J Vet Sci.
- 2014 Dec;15(4):485-493.
- doi: 10.4142/jvs.2014.15.4.485
Cadmium (Cd) is a well-known hepatotoxic environmental pollutant. We used rat hepatocytes as a model to study oxidative damage induced by Cd, effects on the antioxidant systems, and the role... -
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- Relationship between Telomere Maintenance and Liver Disease
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Barnard A, Moch A, Saab S
- KMID: 2434385
- Gut Liver.
- 2019 Jan;13(1):11-15.
- doi: 10.5009/gnl18081
Previous studies have established a correlation between increasing chronological age and risk of cirrhosis. This pattern raised interest in the role of telomeres and the telomerase complex in the pathogenesis... -
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- Hepatocyte Isolation, Culture, and Its Clinical Applications
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Lee DH, Lee KW
- KMID: 2168348
- Hanyang Med Rev.
- 2014 Nov;34(4):165-172.
- doi: 10.7599/hmr.2014.34.4.165
Hepatocytes, parenchymal cells of the liver, are specially differentiated cells to perform most of the body metabolisms. Many clinicians are interested in utilizing hepatocytes as cell therapeutics. A great number... -
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- Relationship between Proliferative Activity and Expression of HBcAg and p53 Protein in Hepatocellular Carcinoma and Surrounding Nontumorous Liver
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Paik SY, Kim HG, Park CI
- KMID: 2275751
- Korean J Pathol.
- 1997 Aug;31(8):773-781.
In an attempt to discover the factors contributing to the increased proliferative activity in hepatocytes and subsequent development of HCC, the proliferative activity of hepatocytes was compared with the size... -
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