Korean J Urol Oncol.
2017 Aug;15(2):51-58. 10.22465/kjuo.2017.15.2.51.
Vascularization Methods for Tissue Engineers
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- 1Department of Urology, Chung-Ang University Hospital, Seoul, Korea. caucih@cau.ac.kr
- KMID: 2391193
- DOI: http://doi.org/10.22465/kjuo.2017.15.2.51
Abstract
- Tissue engineering is limited by our inability to adequately vascularize tissues post implantation because all tissue-engineered substitutes (with the exception of cornea and cartilage) require a vascular network to provide the nutrient and oxygen supply needed for their survival. This review gives a brief overview of the processes and factors involved in the vascularization and angiogenesis and summarizes the different strategies to overcome the issue of slow vascularization and angiogenesis in a range of tissue-engineered substitutes. Moreover, we will announce some potential future plans.
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