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Patient-Specific Tumor Microenvironment Models

Lee JW, Kim J, Shin Y, Chi BH, Kim JH, Chang IH, Choi SY

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Vascularization Methods for Tissue Engineers

Kim MJ, Chi BH, Cho MJ, Whang YM, Chang IH

Tissue engineering is limited by our inability to adequately vascularize tissues post implantation because all tissue-engineered substitutes (with the exception of cornea and cartilage) require a vascular network to provide...
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Erratum: Correction of Acknowledgement. Establishment of an Orthotopic Mouse Non-Muscle Invasive Bladder Cancer Model Expressing the Mammalian Target of Rapamycin Signaling Pathway

Kim SJ, Seo HK, Seo HH, Lee SJ, Kwon JK, Lee TJ, Chi BH, Chang IH

We found an error in our published article.
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Clinical Implications of Urinary Microbiome in Bladder Cancer

Shim JH, Gook JH, Chang IH, Sohn JM, Seong SW, Chi BH

Microbiomes are known to have a beneficial effect on human health by promoting the effective removal of improperly functioning immune cells and protecting the host from pathogen infection. On the...
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Renomedullary Interstitial Cell Tumor Mimicking Renal Cell Carcinoma: A Case Report

Oh H, Park SB, Lee TJ, Chi BH, Park HJ, Lee ES

Renomedullary interstitial cell tumors are often incidentally identified either upon autopsy or kidney resection for other reasons. However, rare renomedullary interstitial cell tumor cases resulting in a clinical symptomatic mass...
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The Overdiagnosis of Kidney Cancer in Koreans and the Active Surveillance on Small Renal Mass

Chi BH, Chang IH

While overtreatment in medical services had been the topic of interest among the medical community for a long time, there are numerous academic papers concerning over-diagnosis nowadays. The use of...
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Application of Bioprinting to Cancer Research

Cho MJ, Chi BH, Kim MJ, Whang YM, Chang IH

Three-dimensional (3D) printing is an additive manufacturing process by which precursor materials are deposited layer by layer to form complex 3D geometries from computer-aided designs, and bioprinting offers the ability...
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Patient-Specific Tumor Microenvironment Models

Lee JW, Kim J, Shin Y, Chi BH, Kim JH, Choi SY

The heterogeneity of cancer makes it difficult to predict the prognosis of treatment. There is still a lack of preclinical model systems that reflect the clinical characteristics of patients who...
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The Present and Future of the Cancer Microenvironment Bioprinting

Cho MJ, Chi BH, Kim MJ, Whang YM, Chang IH

Cancer is the tissue complex consisted with heterogeneous cellular compositions, and microenvironmental cues. During the various stages of cancer initiation, development, and metastasis, cell–cell interactions as well as cell-extracellular matrix...
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Changes in Sexual Function in Benign Prostatic Hyperplasia Patients Taking Dutasteride: 1-Year Follow-Up Results

Chi BH, Kim SC

  • KMID: 2315428
  • Korean J Urol.
  • 2011 Sep;52(9):632-636.
PURPOSE: Sexual adverse events (AEs), a major cause for discontinuing 5alpha-reductase inhibitor (5ARI) therapy for benign prostatic hyperplasia (BPH), are known to occur most frequently early in therapy and appear...
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Warfarin-Induced Penile Necrosis in a Patient with Heparin-Induced Thrombocytopenia

Chang IH, Ha MS, Chi BH, Kown YW, Lee SJ

A 56-yr-old man with lung adenocarcinoma presented with subsegmental pulmonary thrombosis. Platelet count on presentation was 531x10(9)/L. The patient was anticoagulated with subcutaneous low molecular weight heparin (LMWH). Next day,...
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The Internalization of Bacillus Calmette-Guerin (BCG) in Bladder Cancer Cells May be Inhibited by Human beta-defensin 3

Lim SW, Chang IH, Kim TH, Myung SC, Kim KD, Moon YT, Kim JW, Chi BH

PURPOSE: To investigate whether secretion of human beta-defensin 3 (HBD-3) is induced by bacillus Calmette-Guerin (BCG) and to determine whether HBD-3 affects BCG internalization in bladder cancer cells. MATERIALS AND METHODS:...
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The Effects of Recombinant Bacillus Calmette-Guérin Resistant to Antimicrobial Peptides on Orthotopic Bladder Cancer Mouse Model

Hong SJ, Hwang GY, Kang SJ, Choi SY, Chi BH, Chang IH

Purpose: Although Mycobacterium bovis Bacillus Calmette-Guérin (BCG) is the most widely used bladder cancer immunotherapy, innate immune responses involving antimicrobial peptides (AMPs) cause BCG failure. Here, we developed genetically modified...
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Daily Mean Temperature and Urolithiasis Presentation in Six Cities in Korea: Time-Series Analysis

Chi BH, Chang IH, Choi SY, Suh DC, Chang CW, Choi YJ, Lee SY

Seasonal variation in urinary stone presentation is well described in the literature. However, previous studies have some limitations. To explore overall cumulative exposure-response and the heterogeneity in the relationships between...
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Low-Dose Unenhanced Computed Tomography with Iterative Reconstruction for Diagnosis of Ureter Stones

Chi BH, Chang IH, Lee DH, Park SB, Kim KD, Moon YT, Huh TK

PURPOSE: To study the clinical application of low-dose unenhanced computed tomography with iterative reconstruction technique (LDCT-IR) on renal colic in the emergency department. MATERIALS AND METHODS: We conducted a prospective, single-blinded,...
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Low-dose versus standard-dose bacille Calmette–Guérin for non-muscle-invasive bladder cancer: Systematic review and meta-analysis of randomized controlled trials

Choi SY, Ha MS, Kim JH, Chi BH, Kim JW, Chang IH, Kim TH, Myung SC

Purpose: Intravesical BCG (bacille Calmette–Guérin) instillation in patients with non-muscle-invasive bladder cancer decreases the risk for tumor recurrence and progression. After one BCG product was discontinued, a chronic global BCG...
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Daily Mean Temperature Affects Urolithiasis Presentation in Seoul: a Time-series Analysis

Lee S, Kim MS, Kim JH, Kwon JK, Chi BH, Kim JW, Chang IH

This study aimed to investigate the overall cumulative exposure-response and the lag response relationships between daily temperature and urolithiasis presentation in Seoul. Using a time-series design and distributing lag nonlinear...
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Establishment of an Orthotopic Mouse Non-Muscle Invasive Bladder Cancer Model Expressing the Mammalian Target of Rapamycin Signaling Pathway

Kim SJ, Seo HK, Seo HH, Lee SJ, Kwon JK, Lee TJ, Chi BH, Chang IH

We established an orthotopic non-muscle invasive bladder cancer (NMIBC) mouse model expressing the mammalian target of the rapamycin (mTOR) signaling pathway. After intravesical instillation of KU-7-lucs (day 0), animals were...
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P70S6K and Elf4E Dual Inhibition Is Essential to Control Bladder Tumor Growth and Progression in Orthotopic Mouse Non-muscle Invasive Bladder Tumor Model

Chi BH, Kim SJ, Seo HK, Seo HH, Lee SJ, Kwon JK, Lee TJ, Chang IH

We investigated how the dual inhibition of the molecular mechanism of the mammalian target of the rapamycin (mTOR) downstreams, P70S6 kinase (P70S6K) and eukaryotic initiation factor 4E (eIF4E), can lead...
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