J Korean Ophthalmol Soc.  2017 Jun;58(6):712-717. 10.3341/jkos.2017.58.6.712.

Quantitative Pupillometry of the Pupillary Light Reflex in Koreans

• Bak E
• Yoo YJ
• Yang HK
• Hwang JM

• KMID: 2382681
• DOI: http://doi.org/10.3341/jkos.2017.58.6.712

Abstract

PURPOSE
To determine the normal ranges of various indexes of the pupillary light reflex measured by automated pupillometry in Koreans.
METHODS
We retrospectively analyzed 90 healthy adults who did not have any ocular diseases other than refractive errors. The direct pupillary light reflex was measured with an automated dynamic pupillometer (PLR-200, NeurOptics Inc., Irvine, CA, USA). A total of 7 indices were measured as follows; the maximum and minimum pupil diameters, constriction latency, constriction ratio, maximum constriction velocity, average constriction velocity and average dilation velocity.
RESULTS
There were no significant differences in quantitative indexes of the pupillary light reflex between fellow eyes. A significant decrease in maximum pupil diameter, minimum pupil diameter, maximum constriction velocity, average constriction velocity and average dilation velocity were observed with aging. In contrast, a significant increase in constriction latency was observed with aging. There were no differences in quantitative pupil measurements according to gender (p<0.001).
CONCLUSIONS
Quantitative measurements of the pupillary light reflex by dynamic pupillometry showed no significant differences between fellow eyes. A significant decrease in pupil size, constriction velocity and dilation velocity, and an increase in pupil constriction latency were observed with aging.

Keyword

Pupil; Pupillary reflex; Pupillometer

MeSH Terms

Adult
Aging
Constriction
Humans
Pupil
Reference Values
Reflex*
Reflex, Pupillary
Refractive Errors
Retrospective Studies

Figure

• 

  Figure 1 Correlations between age and quantitative measurements of the pupillary light reflex. The maximum pupil diameter (mm) (A), minimum pupil diameter (mm) (B), average constriction velocity (mm/sec) (C), average dilation velocity (mm/sec) (D) and maximum constriction velocity (mm/sec) (E) significantly decreased with age. In contrast, a significant increase in constriction latency (sec) (F) was observed with aging (r = Pearson' correlation coefficient).

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