Korean J Parasitol.  2015 Feb;53(1):105-108. 10.3347/kjp.2015.53.1.105.

Four Additional Cases of Diphyllobothrium nihonkaiense Infection Confirmed by Analysis of COX1 Gene in Korea

  • 1Department of Internal Medicine, Hallym University Chuncheon Sacred Heart Hospital, Chuncheon 200-704, Korea. kimjinbong@hallym.or.kr
  • 2Department of Parasitology and Medical Research Institute, Chungbuk National University College of Medicine, Cheongju 361-763, Korea.


Most of the diphyllobothriid tapeworms isolated from human samples in the Republic of Korea (= Korea) have been identified as Diphyllobothrium nihonkaiense by genetic analysis. This paper reports confirmation of D. nihonkaiense infections in 4 additional human samples obtained between 1995 and 2014, which were analyzed at the Department of Parasitology, Hallym University College of Medicine, Korea. Analysis of the mitochondrial cytochrome c oxidase 1 (cox1) gene revealed a 98.5-99.5% similarity with a reference D. nihonkaiense sequence in GenBank. The present report adds 4 cases of D. nihonkaiense infections to the literature, indicating that the dominant diphyllobothriid tapeworm species in Korea is D. nihonkaiense but not D. latum.


Diphyllobothrium nihonkaiense; Diphyllobothrium latum; cox1 gene
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