Epidemiol Health.  2011;33:e2011010.

Risk Factors for Group B Streptococcus Colonization Among Pregnant Women in Korea

• Kim EJ
• Oh KY
• Kim MY
• Seo YS
• Shin JH
• Song YR
• Yang JH
• Foxman B
• Ki M

Abstract

OBJECTIVES
To identify obstetric and maternal factors related to Group B Streptococcus (GBS) colonization in pregnant women in Korea.
METHODS
The study was conducted between the years 2006-2008 in four hospitals, Cheil and Eulji hospital in Seoul, and Motae and Eulji hospital in Daejeon. We recruited 2,644 pregnant women between 35 to 37 weeks of gestation who had visited for antenatal care. Participants completed a questionnaire, and urine, vaginal and rectal specimens were obtained and cultured using selective broth media. After delivery, medical records were reviewed.
RESULTS
GBS colonization was significantly associated with hospital, age group, education, frequency of pregnancy, and premature rupture of membranes (PROM, more than 18 hours). After adjustment for other variables, Cheil hospital (odds ratio [OR], 2.05; 95% confidence interval [CI], 1.20-3.52), and the first pregnancy (OR, 2.32; 95% CI, 1.12-4.81) remained significant. History of vaginitis showed marginal significance (OR, 1.50; 95% CI, 0.98-2.29).
CONCLUSION
To prevent GBS infection of neonates, clinicians should be alert to the potentially higher risk of GBS colonization in pregnant women in their first pregnancy, and women with premature rupture of membranes (PROM) (18 hours+) or who have a history of vaginitis.

Keyword

Colonization; Pregnant women; Risk factors; Screening; Streptococcus agalactiae

MeSH Terms

Colon
Female
Humans
Infant, Newborn
Korea
Mass Screening
Medical Records
Membranes
Pregnancy
Pregnant Women
Risk Factors
Rupture
Streptococcus
Streptococcus agalactiae
Vaginitis
Surveys and Questionnaires