Korean J Med.  2017 Feb;92(1):36-40. 10.3904/kjm.2017.92.1.36.

The Pathological Diagnosis and Interpretation of Pathological Results: Emphasis on Immunohistochemical Staining

Affiliations
  • 1Department of Pathology, Ajou University School of Medicine, Suwon, Korea. hanpathol@naver.com

Abstract

Hematoxylin and eosin staining is simple and one of the most important techniques in pathological diagnosis. However, it cannot provide complete information about the disease of a patient. Immunohistochemical staining (IHC) is an important method for demonstrating the distribution of a certain molecule or antigen in tissues using specific antigen-antibody reactions. It is used in routine diagnostic work and research to explore biomarkers. In this review, I aim to provide an adequate interpretation of the results of IHC and pathological diagnosis for clinicians.

Keyword

Pathological diagnosis; Immunohistochemical staining

MeSH Terms

Antigen-Antibody Reactions
Biomarkers
Diagnosis*
Eosine Yellowish-(YS)
Hematoxylin
Humans
Methods
Biomarkers
Eosine Yellowish-(YS)
Hematoxylin
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