Korean J Pediatr.
2016 Nov;59(Suppl 1):S96-S98. 10.3345/kjp.2016.59.11.S96.
Relapsed Wilms' tumor with multiple brain metastasis
- Affiliations
-
- 1Department of Neurosurgery, Bahçeşehir University Medical Faculty, Istanbul, Turkey.
- 2Department of Orthopedic Surgery-Spine Center, University of California at San Francisco, San Francisco, CA, USA. muratsakireksi@gmail.com
- 3Department of Pathology, Bahçeşehir University Medical Faculty, Istanbul, Turkey.
- KMID: 2362266
- DOI: http://doi.org/10.3345/kjp.2016.59.11.S96
Abstract
- Wilms' tumor is the most common malignant renal tumor in childhood. The brain metastasis of a Wilms' tumor with anaplastic histopathology is rare. We present the case of an 8-year-old girl with Wilms' tumor, who presented with multiple brain metastases 5 years after her primary diagnosis. The brain masses were diagnosed after a generalized tonic-clonic seizure attack. The big solid mass in the cerebellum was resected, and whole-brain radiotherapy was performed, after which, she succumbed to her disease. In the case of clinical suspicion, cranial surveillance should be included in the routine clinical work-up for Wilms' tumor. Combined aggressive therapy (surgery+radiotherapy+chemotherapy) should be applied whenever possible, for both better survival and palliative aspects.
