Ann Dermatol.  1996 Oct;8(4):269-271. 10.5021/ad.1996.8.4.269.

Subepidermal Calcified Nodule

Abstract

Subepidermal calcified nodule(SCN) is a form of calcinosis cutis which is usually present as a single small, raised, hard nodule with verrucous surface. A 13-year-old girl presented with a 10-month history of a ricegrain-sized, hard, yellowish white papule on both upper eyelids. The lesions were asymptomatic and had increased slowly in size. An excisional biopsy specimen of the left upper eyelid showed acanthosis and narrow pointed rete ridges of the epidermis, and closely aggregated deposition of basophilic material in the uppermost dermis. The material in the dermis did not stain with von Kossa. It was confirmed as calcium deposition by staining with alizarin red S which is far more specific for calcium than the von Kossa stain.

Keyword

Subepidermal calcified nodule; Von Kossa stain; Alizarin red S stain

MeSH Terms

Adolescent
Basophils
Biopsy
Calcinosis
Calcium
Dermis
Epidermis
Eyelids
Female
Humans
Calcium

Cited by  1 articles

A Case of a Subepidermal Calcified Nodule on the Sole without Trauma
In Su Ahn, Bo Young Chung, Hee Bong Lee, Hye One Kim, Hye Kyoung Ahn, Chun Wook Park, Cheol Heon Lee
Ann Dermatol. 2011;23(Suppl 1):S116-S118.    doi: 10.5021/ad.2011.23.S1.S116.

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