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A Case of Severe Lead Poisoning with Basophilic Stippling Teardrop Cell

Kang W, Cho S, Lim DY, Kim S, Park WJ

No abstract available.
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Factors Predicting the Response to Cyclosporin Treatment in Patients With Chronic Spontaneous Urticaria: A Systematic Review

Kulthanan , Subchookul C, Hunnangkul S, Chularojanamontri L, Tuchinda P

PURPOSE: This study aimed to systemically review literature relating to factors that could potentially predict a favorable response to cyclosporine A (CsA) treatment for chronic spontaneous urticaria (CSU). METHODS: A systematic...
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Signals from the various immune cells in promoting food allergy-induced eosinophilic esophagitis like disease

Lianto P, Zhang Y, Che H

Eosinophilic esophagitis (EoE) is a recently recognized esophageal inflammatory disease with clinical manifestations arising from esophageal dysfunction. The etiology of EoE is currently being clarified and food allergy is evolving...
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Emerging Therapies in Chronic Spontaneous Urticaria

Min TK, Saini SS

Chronic spontaneous urticaria (CSU) is characterized by typically short-lived and fleeting wheals, angioedema or both, which occur spontaneously and persist for longer than 6 weeks. This term is applied to...
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Dimerized, Not Monomeric, Translationally Controlled Tumor Protein Induces Basophil Activation and Mast Cell Degranulation in Chronic Urticaria

Ulambayar , Lee H, Yang EM, Park HS, Lee K, Ye YM

Translationally controlled tumor protein (TCTP) is also known as histamine releasing factor as it has the ability to activate mast cells. To investigate the role of TCTP in the pathogenesis...
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Eperisone-Induced Anaphylaxis: Pharmacovigilance Data and Results of Allergy Testing

Park KH, Lee SC, Yuk JE, Kim SR, Lee JH, Park JW

PURPOSE: Eperisone is an oral muscle relaxant used in musculoskeletal disorders causing muscle spasm and pain. For more effective pain control, eperisone is usually prescribed together with nonsteroidal anti-inflammatory drugs...
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Development of a Novel Flow Cytometry-Based System for White Blood Cell Differential Counts: 10-color LeukoDiff

Park D, Chang J, Kahng J, Park H, Jo I, Kim Y, Han K

BACKGROUND: Flow cytometry (FCM) is commonly used to identify many cell populations. We developed a white blood cell (WBC) differential counting system for detecting abnormal cells using FCM incorporating 10...
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Allergy to carminic acid: in vitro evidence of involvement of protein-binding hapten

Osumi M, Yamaguchi , Sugimoto N, Suzukawa M, Arai H, Akiyama H, Nagase H, Ohta K

We previously described a rare case of anaphylaxis presumably induced by carminic acid in cochineal dye used as a food additive. In this study, highly pure carminic acid was added...
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Pollen/Fruit Syndrome: Clinical Relevance of the Cypress Pollen Allergenic Gibberellin-Regulated Protein

Sénéchal H, Keykhosravi S, Couderc R, Selva MA, Shahali Y, Aizawa T, Busnel JM, Arif R, Mercier I, Pham-Thi N, Charpin DA, Poncet P

A pollen/food-associated syndrome (PFAS) has been described between peach and cypress pollen. Cross-reactive allergens were characterized which belong to the Gibberellin-regulated protein (GRP) family, BP14 in cypress pollen and Pru...
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Effects of Ser47-Point Mutation on Conformation Structure and Allergenicity of the Allergen of Der p 2, a Major House Dust Mite Allergen

Kulwanich , Thanyaratsrisakul S, Jirapongsananuruk O, Hales BJ, Thomas WR, Piboonpocanun S

PURPOSE: Hypoallergenic recombinant Der p 2 has been produced by various genetic manipulations, but mutation of a naturally polymorphic amino acid residue known to affect IgE binding has not been...
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Causal Relationship Between Anti-TPO IgE and Chronic Urticaria by In Vitro and In Vivo Tests

Sánchez J, Sánchez A, Cardona R

PURPOSE: Immunoglobulin (Ig) E autoantibodies against thyroid antigens such as thyroid peroxidase (TPO) have been demonstrated in chronic spontaneous urticaria (CSU) patients in higher frequency than healthy subjects. However, if...
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Efficacy and Safety of Sublingual Immunotherapy in Elderly Rhinitis Patients Sensitized to House Dust Mites

Kim JH, Lee JH, Ye YM, Lee JH, Park JW, Hur GY, Kim JH, Lee HY, Shin YS, Yang EM, Park HS

PURPOSE: This study aims to determine the efficacy and safety of house dust mite (HDM)-sublingual immunotherapy (SLIT) in elderly patients with AR. METHODS: A total of 45 patients aged ≥ 60...
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Suppressive Effect of 4-Hydroxy-2-(4-Hydroxyphenethyl) Isoindoline-1,3-Dione on Ovalbumin-Induced Allergic Asthma

Huang J, Su M, Lee BK, Kim MJ, Jung JH, Im DS

4-Hydroxy-2-(4-hydroxyphenethyl)isoindoline-1,3-dione (PD1) is a synthetic phthalimide derivative of a marine compound. PD1 has peroxisome proliferator-activated receptor (PPAR) γ agonistic and anti-inflammatory effects. This study aimed to investigate the effect of...
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Microarray-Based Multivariate Analysis of the Effectiveness of Sublingual Immunotherapy for Cedar Pollinosis

Gotoh M, Kaminuma O, Hiroi T, Okubo K

Sublingual immunotherapy (SLIT) is an effective treatment for allergic diseases. However, the mechanism by which this therapy exhibits its efficacy has not been fully delineated. To elucidate the mechanisms of...
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An unusual dual hypersensitivity reaction to moxifloxacin in a patient

Demir S, Unal D, Olgac M, Akdeniz N, Aktas-Cetin E, Gelincik A, Colakoglu , Buyukozturk S

Both immediate and nonimmediate type hypersensitivity reactions (HRs) with a single dose of quinolone in the same patient have not been previously reported. A 47-year-old female patient referred to us...
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Allergen standardization

Park JW, Jeong KY

Allergen immunotherapy (AIT) and diagnostic tests are based on well qualified allergen extracts, which are derived from biologic organisms. The allergenicity of the extracts is markedly affected by the climate,...
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Inhibitory effect of the aqueous extract of a tetraploid ‘etteum’ variety in Platycodon grandiflorum on degranulation and inflammatory mediator release in RBL-2H3 cells

Jung JI, Kim HS, Ji HK, Lee HS, Lee JY, Kim EJ

PURPOSE: Platycodon grandiflorum (a domestic diploid variety, DV-PG) has been used as a food and component of various traditional oriental medicines. Although DV-PG is known to have an anti-allergic effect,...
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The Effect of Acute Histologic Chorioamnionitis on Hematologic Profile of Preterm Fetuses

Kang HS, Park JW, Kim HS

OBJECTIVE: To characterize the hematologic profile of preterm fetuses delivered spontaneously with acute histologic chorioamnionitis (HCA). METHODS: This was a retrospective cohort study. The relationship between the presence of acute HCA...
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Haemoproteus in barn and collared scops owls from Thailand

Salakij C, Pornpanom , Lertwatcharasarakul P, Kasorndorkbua C, Salakij J

The barn owl (BO) and the collared scops owl (CSO) are common nocturnal raptors throughout Thailand. Blood samples from 23 adult BOs and 14 CSOs were collected and processed for...
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Changes in basophil activation during immunotherapy with house dust mite and mugwort in patients with allergic rhinitis

Kim SH, Kim SH, Chung SJ, Kim JH, Lee SY, Kim BK, Lim KW, Chang YS

BACKGROUND: The basophil activation test (BAT) is a promising tool for monitoring allergen-specific immunotherapy responses. OBJECTIVE: We aimed to investigate the changes in basophil activation in response to the inhalant allergens...
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